Association between ABO blood group and rheumatic diseases is not well characterized. This study assessed distribution of ABO blood group and Rh factor in patients with rheumatic diseases and healthy blood donors. We retrospectively evaluated data of patients with rheumatic diseases who attended the hospital from September 2015 to January 2020, and the documented evidence of blood group of healthy blood donors. Data from 5000 healthy donors and 3165 patients with rheumatic disease were assessed. Overall, blood type O was the most prevalent (42.94% and 43.14%) followed by B (33.21% and 30.08%), A (17.66% and 21.48%) and AB (6.19% and 5.30%) in patients with rheumatic disease and healthy donors, respectively. This distribution was statistically different between the groups, with blood group A being more common in healthy donors than in patients with rheumatic disease (P<0.0001). Distribution of ABO groups among rheumatic disease types was similar (P=0.2921). More individuals had Rhesus (Rh) (+) factor (93.97%) than Rh (-) (6.03%), however, its distribution was comparable across healthy donors and patients with rheumatic disease (P=0.1145). Patients with blood group A had significantly lower risk of developing rheumatic diseases compared to blood group O (OR [95% CI]: 0.94 [0.780, 1.134]; P<0.0318). Similarly, patients bearing blood type A+ (0.98 [0.62, 1.54]; P=0.0037) and O+ (1.08 [0.694, 1.68]; P=0.0215) were at a lower risk for developing rheumatic diseases compared to those with O- blood group. The most common blood type was O followed by B, A and AB in patients with rheumatic disease and healthy donors. Individuals with blood group A had lower risk of developing rheumatic diseases compared to other blood types.
| Published in | American Journal of Internal Medicine (Volume 9, Issue 3) |
| DOI | 10.11648/j.ajim.20210903.11 |
| Page(s) | 107-113 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
ABO Blood-group System, Blood Donors, Blood Groups, Rheumatic Diseases
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APA Style
Arindam Nandy Roy, Yarram Ashok Kumar, Regina Lata Thadigiri. (2021). A Retrospective Observational Study Comparing ABO Blood Group and Rh Factor Distribution in Patients with Rheumatic Diseases and Healthy Donors in Southern India. American Journal of Internal Medicine, 9(3), 107-113. https://doi.org/10.11648/j.ajim.20210903.11
ACS Style
Arindam Nandy Roy; Yarram Ashok Kumar; Regina Lata Thadigiri. A Retrospective Observational Study Comparing ABO Blood Group and Rh Factor Distribution in Patients with Rheumatic Diseases and Healthy Donors in Southern India. Am. J. Intern. Med. 2021, 9(3), 107-113. doi: 10.11648/j.ajim.20210903.11
AMA Style
Arindam Nandy Roy, Yarram Ashok Kumar, Regina Lata Thadigiri. A Retrospective Observational Study Comparing ABO Blood Group and Rh Factor Distribution in Patients with Rheumatic Diseases and Healthy Donors in Southern India. Am J Intern Med. 2021;9(3):107-113. doi: 10.11648/j.ajim.20210903.11
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Download@article{10.11648/j.ajim.20210903.11,
author = {Arindam Nandy Roy and Yarram Ashok Kumar and Regina Lata Thadigiri},
title = {A Retrospective Observational Study Comparing ABO Blood Group and Rh Factor Distribution in Patients with Rheumatic Diseases and Healthy Donors in Southern India},
journal = {American Journal of Internal Medicine},
volume = {9},
number = {3},
pages = {107-113},
doi = {10.11648/j.ajim.20210903.11},
url = {https://doi.org/10.11648/j.ajim.20210903.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20210903.11},
abstract = {Association between ABO blood group and rheumatic diseases is not well characterized. This study assessed distribution of ABO blood group and Rh factor in patients with rheumatic diseases and healthy blood donors. We retrospectively evaluated data of patients with rheumatic diseases who attended the hospital from September 2015 to January 2020, and the documented evidence of blood group of healthy blood donors. Data from 5000 healthy donors and 3165 patients with rheumatic disease were assessed. Overall, blood type O was the most prevalent (42.94% and 43.14%) followed by B (33.21% and 30.08%), A (17.66% and 21.48%) and AB (6.19% and 5.30%) in patients with rheumatic disease and healthy donors, respectively. This distribution was statistically different between the groups, with blood group A being more common in healthy donors than in patients with rheumatic disease (PP=0.2921). More individuals had Rhesus (Rh) (+) factor (93.97%) than Rh (-) (6.03%), however, its distribution was comparable across healthy donors and patients with rheumatic disease (P=0.1145). Patients with blood group A had significantly lower risk of developing rheumatic diseases compared to blood group O (OR [95% CI]: 0.94 [0.780, 1.134]; PP=0.0037) and O+ (1.08 [0.694, 1.68]; P=0.0215) were at a lower risk for developing rheumatic diseases compared to those with O- blood group. The most common blood type was O followed by B, A and AB in patients with rheumatic disease and healthy donors. Individuals with blood group A had lower risk of developing rheumatic diseases compared to other blood types.},
year = {2021}
}
TY - JOUR T1 - A Retrospective Observational Study Comparing ABO Blood Group and Rh Factor Distribution in Patients with Rheumatic Diseases and Healthy Donors in Southern India AU - Arindam Nandy Roy AU - Yarram Ashok Kumar AU - Regina Lata Thadigiri Y1 - 2021/04/29 PY - 2021 N1 - https://doi.org/10.11648/j.ajim.20210903.11 DO - 10.11648/j.ajim.20210903.11 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 107 EP - 113 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20210903.11 AB - Association between ABO blood group and rheumatic diseases is not well characterized. This study assessed distribution of ABO blood group and Rh factor in patients with rheumatic diseases and healthy blood donors. We retrospectively evaluated data of patients with rheumatic diseases who attended the hospital from September 2015 to January 2020, and the documented evidence of blood group of healthy blood donors. Data from 5000 healthy donors and 3165 patients with rheumatic disease were assessed. Overall, blood type O was the most prevalent (42.94% and 43.14%) followed by B (33.21% and 30.08%), A (17.66% and 21.48%) and AB (6.19% and 5.30%) in patients with rheumatic disease and healthy donors, respectively. This distribution was statistically different between the groups, with blood group A being more common in healthy donors than in patients with rheumatic disease (PP=0.2921). More individuals had Rhesus (Rh) (+) factor (93.97%) than Rh (-) (6.03%), however, its distribution was comparable across healthy donors and patients with rheumatic disease (P=0.1145). Patients with blood group A had significantly lower risk of developing rheumatic diseases compared to blood group O (OR [95% CI]: 0.94 [0.780, 1.134]; PP=0.0037) and O+ (1.08 [0.694, 1.68]; P=0.0215) were at a lower risk for developing rheumatic diseases compared to those with O- blood group. The most common blood type was O followed by B, A and AB in patients with rheumatic disease and healthy donors. Individuals with blood group A had lower risk of developing rheumatic diseases compared to other blood types. VL - 9 IS - 3 ER -
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