Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo

Blaise Makoso Nimi; Benjamin Longo Mbenza; Timothee Mawisa Nkemfuni; Steve Tulantched Mingana; Gaston Katomba Zeba; Piroger Phoba Mbadu; Firmin Mbambi Nsungu; Fabrice Nlandu Makungu; Christian Kisoka Lusunsi

doi:doi:10.11648/j.ajim.20221003.14

Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo

Blaise Makoso Nimi, Benjamin Longo Mbenza, Timothee Mawisa Nkemfuni, Steve Tulantched Mingana, Gaston Katomba Zeba, Piroger Phoba Mbadu, Firmin Mbambi Nsungu, Fabrice Nlandu Makungu, Christian Kisoka Lusunsi

Published in American Journal of Internal Medicine (Volume 10, Issue 3)

Received: 9 March 2022 Accepted: 25 March 2022 Published: 24 May 2022

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Abstract

Background and aims: the whole of humanity has experienced since December 2019 a pandemic of coronavirus disease 2019 (COVID-19), caused by the coronavirus. Unprecedented situation in this century especially for the DR Congo with a less equipped health system. The objective of this study is to describe the clinico-biological profile of patients hospitalized at the Cinquantenaire Hospital of Kinshasa in DR Congo. Methods: This was a retrospective, analytical and descriptive cohort study carried out among 360 patients hospitalized at the Cinquantenaire Hospital in Kinshasa from the period from April 18, 2020 to July 10, 2021. Results: The average age was 42.7 ± 12.0 years with a female predominance, 57.7% of patients were over 50 years old. Comorbidities such as hypertension, diabetes mellitus and bronchial asthma were present respectively in 25.2% and 4.2% and 12.3%. The symptomatology was dominated by cough, fever and asthenia in more than The most common biological abnormalities were as follows: increased CRP (57.7%), basocytaemia (55%), hepatic cytolysis (20.6%), elevated D-dimer (15.3%), decreased TP (17.5%) lymphopenia (16.7%), anemia (11.1%) and Hyperleukocytosis 10.6% Conclusion: COVID-19 infection should be considered as sepsis with multi-visceral involvement although the lung is first. Both biological and hematological abnormalities may be encountered.

Published in	American Journal of Internal Medicine (Volume 10, Issue 3)
DOI	10.11648/j.ajim.20221003.14
Page(s)	56-61
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

COVID-19, Symptoms, Biology

References

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Blaise Makoso Nimi, Benjamin Longo Mbenza, Timothee Mawisa Nkemfuni, Steve Tulantched Mingana, Gaston Katomba Zeba, et al. (2022). Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo. American Journal of Internal Medicine, 10(3), 56-61. https://doi.org/10.11648/j.ajim.20221003.14

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ACS Style

Blaise Makoso Nimi; Benjamin Longo Mbenza; Timothee Mawisa Nkemfuni; Steve Tulantched Mingana; Gaston Katomba Zeba, et al. Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo. Am. J. Intern. Med. 2022, 10(3), 56-61. doi: 10.11648/j.ajim.20221003.14

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AMA Style

Blaise Makoso Nimi, Benjamin Longo Mbenza, Timothee Mawisa Nkemfuni, Steve Tulantched Mingana, Gaston Katomba Zeba, et al. Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo. Am J Intern Med. 2022;10(3):56-61. doi: 10.11648/j.ajim.20221003.14

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@article{10.11648/j.ajim.20221003.14,
  author = {Blaise Makoso Nimi and Benjamin Longo Mbenza and Timothee Mawisa Nkemfuni and Steve Tulantched Mingana and Gaston Katomba Zeba and Piroger Phoba Mbadu and Firmin Mbambi Nsungu and Fabrice Nlandu Makungu and Christian Kisoka Lusunsi},
  title = {Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo},
  journal = {American Journal of Internal Medicine},
  volume = {10},
  number = {3},
  pages = {56-61},
  doi = {10.11648/j.ajim.20221003.14},
  url = {https://doi.org/10.11648/j.ajim.20221003.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20221003.14},
  abstract = {Background and aims: the whole of humanity has experienced since December 2019 a pandemic of coronavirus disease 2019 (COVID-19), caused by the coronavirus. Unprecedented situation in this century especially for the DR Congo with a less equipped health system. The objective of this study is to describe the clinico-biological profile of patients hospitalized at the Cinquantenaire Hospital of Kinshasa in DR Congo. Methods: This was a retrospective, analytical and descriptive cohort study carried out among 360 patients hospitalized at the Cinquantenaire Hospital in Kinshasa from the period from April 18, 2020 to July 10, 2021. Results: The average age was 42.7 ± 12.0 years with a female predominance, 57.7% of patients were over 50 years old. Comorbidities such as hypertension, diabetes mellitus and bronchial asthma were present respectively in 25.2% and 4.2% and 12.3%. The symptomatology was dominated by cough, fever and asthenia in more than The most common biological abnormalities were as follows: increased CRP (57.7%), basocytaemia (55%), hepatic cytolysis (20.6%), elevated D-dimer (15.3%), decreased TP (17.5%) lymphopenia (16.7%), anemia (11.1%) and Hyperleukocytosis 10.6% Conclusion: COVID-19 infection should be considered as sepsis with multi-visceral involvement although the lung is first. Both biological and hematological abnormalities may be encountered.},
 year = {2022}
}

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TY  - JOUR
T1  - Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo
AU  - Blaise Makoso Nimi
AU  - Benjamin Longo Mbenza
AU  - Timothee Mawisa Nkemfuni
AU  - Steve Tulantched Mingana
AU  - Gaston Katomba Zeba
AU  - Piroger Phoba Mbadu
AU  - Firmin Mbambi Nsungu
AU  - Fabrice Nlandu Makungu
AU  - Christian Kisoka Lusunsi
Y1  - 2022/05/24
PY  - 2022
N1  - https://doi.org/10.11648/j.ajim.20221003.14
DO  - 10.11648/j.ajim.20221003.14
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 56
EP  - 61
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20221003.14
AB  - Background and aims: the whole of humanity has experienced since December 2019 a pandemic of coronavirus disease 2019 (COVID-19), caused by the coronavirus. Unprecedented situation in this century especially for the DR Congo with a less equipped health system. The objective of this study is to describe the clinico-biological profile of patients hospitalized at the Cinquantenaire Hospital of Kinshasa in DR Congo. Methods: This was a retrospective, analytical and descriptive cohort study carried out among 360 patients hospitalized at the Cinquantenaire Hospital in Kinshasa from the period from April 18, 2020 to July 10, 2021. Results: The average age was 42.7 ± 12.0 years with a female predominance, 57.7% of patients were over 50 years old. Comorbidities such as hypertension, diabetes mellitus and bronchial asthma were present respectively in 25.2% and 4.2% and 12.3%. The symptomatology was dominated by cough, fever and asthenia in more than The most common biological abnormalities were as follows: increased CRP (57.7%), basocytaemia (55%), hepatic cytolysis (20.6%), elevated D-dimer (15.3%), decreased TP (17.5%) lymphopenia (16.7%), anemia (11.1%) and Hyperleukocytosis 10.6% Conclusion: COVID-19 infection should be considered as sepsis with multi-visceral involvement although the lung is first. Both biological and hematological abnormalities may be encountered.
VL  - 10
IS  - 3
ER  -

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Author Information

Blaise Makoso Nimi

Department of Internal Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo
Benjamin Longo Mbenza

Department of Internal Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo
Timothee Mawisa Nkemfuni

Department of Anesthesia and Resuscitation, Cinquantenaire Hospital, Kinshasa, Democratic Republic of Congo
Steve Tulantched Mingana

Department of Anesthesia and Resuscitation, Cinquantenaire Hospital, Kinshasa, Democratic Republic of Congo
Gaston Katomba Zeba

Department of Internal Medicine, University of President Joseph Kasa-Vubu, Boma, Democratic Republic of Congo
Piroger Phoba Mbadu

Department of Internal Medicine, University of President Joseph Kasa-Vubu, Boma, Democratic Republic of Congo
Firmin Mbambi Nsungu

Department of Internal Medicine, University of President Joseph Kasa-Vubu, Boma, Democratic Republic of Congo
Fabrice Nlandu Makungu

Department of Internal Medicine, University of President Joseph Kasa-Vubu, Boma, Democratic Republic of Congo
Christian Kisoka Lusunsi

Departement of Public Health, Lomo-University Research, Kinshasa, Democratic Republic of Congo

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APA Style

Blaise Makoso Nimi, Benjamin Longo Mbenza, Timothee Mawisa Nkemfuni, Steve Tulantched Mingana, Gaston Katomba Zeba, et al. (2022). Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo. American Journal of Internal Medicine, 10(3), 56-61. https://doi.org/10.11648/j.ajim.20221003.14

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ACS Style

Blaise Makoso Nimi; Benjamin Longo Mbenza; Timothee Mawisa Nkemfuni; Steve Tulantched Mingana; Gaston Katomba Zeba, et al. Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo. Am. J. Intern. Med. 2022, 10(3), 56-61. doi: 10.11648/j.ajim.20221003.14

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AMA Style

Blaise Makoso Nimi, Benjamin Longo Mbenza, Timothee Mawisa Nkemfuni, Steve Tulantched Mingana, Gaston Katomba Zeba, et al. Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo. Am J Intern Med. 2022;10(3):56-61. doi: 10.11648/j.ajim.20221003.14

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@article{10.11648/j.ajim.20221003.14,
  author = {Blaise Makoso Nimi and Benjamin Longo Mbenza and Timothee Mawisa Nkemfuni and Steve Tulantched Mingana and Gaston Katomba Zeba and Piroger Phoba Mbadu and Firmin Mbambi Nsungu and Fabrice Nlandu Makungu and Christian Kisoka Lusunsi},
  title = {Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo},
  journal = {American Journal of Internal Medicine},
  volume = {10},
  number = {3},
  pages = {56-61},
  doi = {10.11648/j.ajim.20221003.14},
  url = {https://doi.org/10.11648/j.ajim.20221003.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20221003.14},
  abstract = {Background and aims: the whole of humanity has experienced since December 2019 a pandemic of coronavirus disease 2019 (COVID-19), caused by the coronavirus. Unprecedented situation in this century especially for the DR Congo with a less equipped health system. The objective of this study is to describe the clinico-biological profile of patients hospitalized at the Cinquantenaire Hospital of Kinshasa in DR Congo. Methods: This was a retrospective, analytical and descriptive cohort study carried out among 360 patients hospitalized at the Cinquantenaire Hospital in Kinshasa from the period from April 18, 2020 to July 10, 2021. Results: The average age was 42.7 ± 12.0 years with a female predominance, 57.7% of patients were over 50 years old. Comorbidities such as hypertension, diabetes mellitus and bronchial asthma were present respectively in 25.2% and 4.2% and 12.3%. The symptomatology was dominated by cough, fever and asthenia in more than The most common biological abnormalities were as follows: increased CRP (57.7%), basocytaemia (55%), hepatic cytolysis (20.6%), elevated D-dimer (15.3%), decreased TP (17.5%) lymphopenia (16.7%), anemia (11.1%) and Hyperleukocytosis 10.6% Conclusion: COVID-19 infection should be considered as sepsis with multi-visceral involvement although the lung is first. Both biological and hematological abnormalities may be encountered.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - Clinical Presentation and Biological Modification of Hospitalized Patients for COVID-19 in the Democratic Republic of Congo
AU  - Blaise Makoso Nimi
AU  - Benjamin Longo Mbenza
AU  - Timothee Mawisa Nkemfuni
AU  - Steve Tulantched Mingana
AU  - Gaston Katomba Zeba
AU  - Piroger Phoba Mbadu
AU  - Firmin Mbambi Nsungu
AU  - Fabrice Nlandu Makungu
AU  - Christian Kisoka Lusunsi
Y1  - 2022/05/24
PY  - 2022
N1  - https://doi.org/10.11648/j.ajim.20221003.14
DO  - 10.11648/j.ajim.20221003.14
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 56
EP  - 61
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20221003.14
AB  - Background and aims: the whole of humanity has experienced since December 2019 a pandemic of coronavirus disease 2019 (COVID-19), caused by the coronavirus. Unprecedented situation in this century especially for the DR Congo with a less equipped health system. The objective of this study is to describe the clinico-biological profile of patients hospitalized at the Cinquantenaire Hospital of Kinshasa in DR Congo. Methods: This was a retrospective, analytical and descriptive cohort study carried out among 360 patients hospitalized at the Cinquantenaire Hospital in Kinshasa from the period from April 18, 2020 to July 10, 2021. Results: The average age was 42.7 ± 12.0 years with a female predominance, 57.7% of patients were over 50 years old. Comorbidities such as hypertension, diabetes mellitus and bronchial asthma were present respectively in 25.2% and 4.2% and 12.3%. The symptomatology was dominated by cough, fever and asthenia in more than The most common biological abnormalities were as follows: increased CRP (57.7%), basocytaemia (55%), hepatic cytolysis (20.6%), elevated D-dimer (15.3%), decreased TP (17.5%) lymphopenia (16.7%), anemia (11.1%) and Hyperleukocytosis 10.6% Conclusion: COVID-19 infection should be considered as sepsis with multi-visceral involvement although the lung is first. Both biological and hematological abnormalities may be encountered.
VL  - 10
IS  - 3
ER  -

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