Buerger's disease is a systemic vasculitis strongly correlated with tobacco use. It entails a heavy socio-occupational impact. We report the case of a 26-year-old patient with ischemia of the lower limbs revealing Buerger’s disease. He is known smoker with passive exposure to Indian hemp. He was seen for ischemic foot pain that had been progressing for a year. Involvement began in the left big toe. Subsequently, hyperalgesic necrotic lesions were observed on the 3rd, 4th and 5th toes of the foot. Biological investigations revealed an inflammatory syndrome with normocytic anemia and increased C-reactive protein. Retroviral, syphilitic, Hepatitis B and C viruses and SARS-CoV-2 serologies were negative. Antinuclear antibodies were initially borderline at 100 IU with speckled fluorescence, then negative on control. Neutrophil cytoplasmic antibodies and antiphospholipid antibodies were negative. Investigation of thrombophilia was non-contributory, notably factor V mutation testing, antithrombin III assay, proteins C and S and fibrinogen. An arterial ultrasound revealed extensive arterial thrombosis with thickening of the femoral arterial vessel walls. Thromboangiitis obliterans was confirmed and the patient was put on corticosteroids and adjuvant therapy. Surgical treatment was performed 4 months later. Buerger's disease is a serious vascular disorder which must be diagnosed very early in order to prevent complications. Early smoking cessation leads to remission in the early phase.
Published in | American Journal of Internal Medicine (Volume 12, Issue 5) |
DOI | 10.11648/j.ajim.20241205.12 |
Page(s) | 74-77 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2024. Published by Science Publishing Group |
Thromboangiitis Obliterans, Buerger's, Tobacco, Amputation
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APA Style
Mansour, D. B., Ndour, J. N., Yanidou, N., Faye, F. F. A., Diop, M. M., et al. (2024). Peripheral Ischemia and Necrosis Revealing Buerger's Disease in an Internal Medicine Department. American Journal of Internal Medicine, 12(5), 74-77. https://doi.org/10.11648/j.ajim.20241205.12
ACS Style
Mansour, D. B.; Ndour, J. N.; Yanidou, N.; Faye, F. F. A.; Diop, M. M., et al. Peripheral Ischemia and Necrosis Revealing Buerger's Disease in an Internal Medicine Department. Am. J. Intern. Med. 2024, 12(5), 74-77. doi: 10.11648/j.ajim.20241205.12
@article{10.11648/j.ajim.20241205.12, author = {Diallo Bachir Mansour and Jean Noel Ndour and Ndiaye Yanidou and Faye Fulgence Abdou Faye and Moustapha Mbacke Diop and Aboubakry Sow and Nana Mamoudou Baba and Wade Adama and Mbaye Serigne Abdou Khadr and Diack Mamadou and Berthé Adama and Touré Papa Souleymane and Diop Madoky Magatte and Ka Mamadou Mourtalla}, title = {Peripheral Ischemia and Necrosis Revealing Buerger's Disease in an Internal Medicine Department }, journal = {American Journal of Internal Medicine}, volume = {12}, number = {5}, pages = {74-77}, doi = {10.11648/j.ajim.20241205.12}, url = {https://doi.org/10.11648/j.ajim.20241205.12}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20241205.12}, abstract = {Buerger's disease is a systemic vasculitis strongly correlated with tobacco use. It entails a heavy socio-occupational impact. We report the case of a 26-year-old patient with ischemia of the lower limbs revealing Buerger’s disease. He is known smoker with passive exposure to Indian hemp. He was seen for ischemic foot pain that had been progressing for a year. Involvement began in the left big toe. Subsequently, hyperalgesic necrotic lesions were observed on the 3rd, 4th and 5th toes of the foot. Biological investigations revealed an inflammatory syndrome with normocytic anemia and increased C-reactive protein. Retroviral, syphilitic, Hepatitis B and C viruses and SARS-CoV-2 serologies were negative. Antinuclear antibodies were initially borderline at 100 IU with speckled fluorescence, then negative on control. Neutrophil cytoplasmic antibodies and antiphospholipid antibodies were negative. Investigation of thrombophilia was non-contributory, notably factor V mutation testing, antithrombin III assay, proteins C and S and fibrinogen. An arterial ultrasound revealed extensive arterial thrombosis with thickening of the femoral arterial vessel walls. Thromboangiitis obliterans was confirmed and the patient was put on corticosteroids and adjuvant therapy. Surgical treatment was performed 4 months later. Buerger's disease is a serious vascular disorder which must be diagnosed very early in order to prevent complications. Early smoking cessation leads to remission in the early phase. }, year = {2024} }
TY - JOUR T1 - Peripheral Ischemia and Necrosis Revealing Buerger's Disease in an Internal Medicine Department AU - Diallo Bachir Mansour AU - Jean Noel Ndour AU - Ndiaye Yanidou AU - Faye Fulgence Abdou Faye AU - Moustapha Mbacke Diop AU - Aboubakry Sow AU - Nana Mamoudou Baba AU - Wade Adama AU - Mbaye Serigne Abdou Khadr AU - Diack Mamadou AU - Berthé Adama AU - Touré Papa Souleymane AU - Diop Madoky Magatte AU - Ka Mamadou Mourtalla Y1 - 2024/10/18 PY - 2024 N1 - https://doi.org/10.11648/j.ajim.20241205.12 DO - 10.11648/j.ajim.20241205.12 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 74 EP - 77 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20241205.12 AB - Buerger's disease is a systemic vasculitis strongly correlated with tobacco use. It entails a heavy socio-occupational impact. We report the case of a 26-year-old patient with ischemia of the lower limbs revealing Buerger’s disease. He is known smoker with passive exposure to Indian hemp. He was seen for ischemic foot pain that had been progressing for a year. Involvement began in the left big toe. Subsequently, hyperalgesic necrotic lesions were observed on the 3rd, 4th and 5th toes of the foot. Biological investigations revealed an inflammatory syndrome with normocytic anemia and increased C-reactive protein. Retroviral, syphilitic, Hepatitis B and C viruses and SARS-CoV-2 serologies were negative. Antinuclear antibodies were initially borderline at 100 IU with speckled fluorescence, then negative on control. Neutrophil cytoplasmic antibodies and antiphospholipid antibodies were negative. Investigation of thrombophilia was non-contributory, notably factor V mutation testing, antithrombin III assay, proteins C and S and fibrinogen. An arterial ultrasound revealed extensive arterial thrombosis with thickening of the femoral arterial vessel walls. Thromboangiitis obliterans was confirmed and the patient was put on corticosteroids and adjuvant therapy. Surgical treatment was performed 4 months later. Buerger's disease is a serious vascular disorder which must be diagnosed very early in order to prevent complications. Early smoking cessation leads to remission in the early phase. VL - 12 IS - 5 ER -