Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy

Amal Mohamed Gamal; Sanaa Ibrahim Abd El-Gaffar

doi:doi:10.11648/j.ajns.20150404.16

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Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy

Amal Mohamed Gamal, Sanaa Ibrahim Abd El-Gaffar

Published in American Journal of Nursing Science (Volume 4, Issue 4)

Received: 31 May 2015 Accepted: 11 June 2015 Published: 4 July 2015

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Abstract

Aim of the study was to determine the impact of stress on immune responses of breast cancer women after Mastectomy Materials and method: study was carried out on a convenient sample of 60 adult women diagnosed as breast cancer for stage II or III and scheduled for mastectomy at Oncology University Hospital of Menoufia A descriptive design was used. Two tools; were utilized to collect data related to this study were (1) Stress Assessment Scale, and (2) Immune Response Assessment Questionnaire. Results: revealed that 46.7% of breast cancer women in the study aged between (45 – to less than 55) years, 80.0% were married, 63.3% lived in rural areas, 50.0% monthly income between (150 – less than 300) Egyptian pounds, 40.0% were illiterate, 36.7% of the sample had sever degree of stress at preoperative assessment while 56.7% had sever degree of stress at post operative assessment, there was negative statistically significant correlations between total stress and immune responses were T lymphocytes, CD4 helper, CD56 NK cell, and CD14 Monocytes in pre operative assessment. And T lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cell, and CD14 Monocytes in post operative assessment. Conclusions: the higher the degree of stress, the lower the values of T Lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cells, and CD14 Monocytes. Supporting cancer women during treatments through instructing their psychological and physical well-being. Recommendation: Further researches are needed with large sample size and control group.

Published in	American Journal of Nursing Science (Volume 4, Issue 4)
DOI	10.11648/j.ajns.20150404.16
Page(s)	182-189
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Breast Cancer. Women, Immune Response, Mastectomy, Stress

References

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APA Style

Amal Mohamed Gamal, Sanaa Ibrahim Abd El-Gaffar. (2015). Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy. American Journal of Nursing Science, 4(4), 182-189. https://doi.org/10.11648/j.ajns.20150404.16

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ACS Style

Amal Mohamed Gamal; Sanaa Ibrahim Abd El-Gaffar. Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy. Am. J. Nurs. Sci. 2015, 4(4), 182-189. doi: 10.11648/j.ajns.20150404.16

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AMA Style

Amal Mohamed Gamal, Sanaa Ibrahim Abd El-Gaffar. Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy. Am J Nurs Sci. 2015;4(4):182-189. doi: 10.11648/j.ajns.20150404.16

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@article{10.11648/j.ajns.20150404.16,
  author = {Amal Mohamed Gamal and Sanaa Ibrahim Abd El-Gaffar},
  title = {Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy},
  journal = {American Journal of Nursing Science},
  volume = {4},
  number = {4},
  pages = {182-189},
  doi = {10.11648/j.ajns.20150404.16},
  url = {https://doi.org/10.11648/j.ajns.20150404.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20150404.16},
  abstract = {Aim of the study was to determine the impact of stress on immune responses of breast cancer women after Mastectomy Materials and method: study was carried out on a convenient sample of 60 adult women diagnosed as breast cancer for stage II or III and scheduled for mastectomy at Oncology University Hospital of Menoufia A descriptive design was used. Two tools; were utilized to collect data related to this study were (1) Stress Assessment Scale, and (2) Immune Response Assessment Questionnaire. Results: revealed that 46.7% of breast cancer women in the study aged between (45 – to less than 55) years, 80.0% were married, 63.3% lived in rural areas, 50.0% monthly income between (150 – less than 300) Egyptian pounds, 40.0% were illiterate, 36.7% of the sample had sever degree of stress at preoperative assessment while 56.7% had sever degree of stress at post operative assessment, there was negative statistically significant correlations between total stress and immune responses were T lymphocytes, CD4 helper, CD56 NK cell, and CD14 Monocytes in pre operative assessment. And T lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cell, and CD14 Monocytes in post operative assessment. Conclusions: the higher the degree of stress, the lower the values of T Lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cells, and CD14 Monocytes. Supporting cancer women during treatments through instructing their psychological and physical well-being. Recommendation: Further researches are needed with large sample size and control group.},
 year = {2015}
}

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TY  - JOUR
T1  - Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy
AU  - Amal Mohamed Gamal
AU  - Sanaa Ibrahim Abd El-Gaffar
Y1  - 2015/07/04
PY  - 2015
N1  - https://doi.org/10.11648/j.ajns.20150404.16
DO  - 10.11648/j.ajns.20150404.16
T2  - American Journal of Nursing Science
JF  - American Journal of Nursing Science
JO  - American Journal of Nursing Science
SP  - 182
EP  - 189
PB  - Science Publishing Group
SN  - 2328-5753
UR  - https://doi.org/10.11648/j.ajns.20150404.16
AB  - Aim of the study was to determine the impact of stress on immune responses of breast cancer women after Mastectomy Materials and method: study was carried out on a convenient sample of 60 adult women diagnosed as breast cancer for stage II or III and scheduled for mastectomy at Oncology University Hospital of Menoufia A descriptive design was used. Two tools; were utilized to collect data related to this study were (1) Stress Assessment Scale, and (2) Immune Response Assessment Questionnaire. Results: revealed that 46.7% of breast cancer women in the study aged between (45 – to less than 55) years, 80.0% were married, 63.3% lived in rural areas, 50.0% monthly income between (150 – less than 300) Egyptian pounds, 40.0% were illiterate, 36.7% of the sample had sever degree of stress at preoperative assessment while 56.7% had sever degree of stress at post operative assessment, there was negative statistically significant correlations between total stress and immune responses were T lymphocytes, CD4 helper, CD56 NK cell, and CD14 Monocytes in pre operative assessment. And T lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cell, and CD14 Monocytes in post operative assessment. Conclusions: the higher the degree of stress, the lower the values of T Lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cells, and CD14 Monocytes. Supporting cancer women during treatments through instructing their psychological and physical well-being. Recommendation: Further researches are needed with large sample size and control group.
VL  - 4
IS  - 4
ER  -

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Author Information

Amal Mohamed Gamal

Maternity &Newborn Health Nursing Department, Faculty of Nursing, Menoufia University, Menoufia, Egypt
Sanaa Ibrahim Abd El-Gaffar

Medical Surgical Nursing Departmen, Faculty of Nursing, Menoufia University, Menoufia, Egypt

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APA Style

Amal Mohamed Gamal, Sanaa Ibrahim Abd El-Gaffar. (2015). Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy. American Journal of Nursing Science, 4(4), 182-189. https://doi.org/10.11648/j.ajns.20150404.16

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ACS Style

Amal Mohamed Gamal; Sanaa Ibrahim Abd El-Gaffar. Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy. Am. J. Nurs. Sci. 2015, 4(4), 182-189. doi: 10.11648/j.ajns.20150404.16

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AMA Style

Amal Mohamed Gamal, Sanaa Ibrahim Abd El-Gaffar. Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy. Am J Nurs Sci. 2015;4(4):182-189. doi: 10.11648/j.ajns.20150404.16

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@article{10.11648/j.ajns.20150404.16,
  author = {Amal Mohamed Gamal and Sanaa Ibrahim Abd El-Gaffar},
  title = {Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy},
  journal = {American Journal of Nursing Science},
  volume = {4},
  number = {4},
  pages = {182-189},
  doi = {10.11648/j.ajns.20150404.16},
  url = {https://doi.org/10.11648/j.ajns.20150404.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20150404.16},
  abstract = {Aim of the study was to determine the impact of stress on immune responses of breast cancer women after Mastectomy Materials and method: study was carried out on a convenient sample of 60 adult women diagnosed as breast cancer for stage II or III and scheduled for mastectomy at Oncology University Hospital of Menoufia A descriptive design was used. Two tools; were utilized to collect data related to this study were (1) Stress Assessment Scale, and (2) Immune Response Assessment Questionnaire. Results: revealed that 46.7% of breast cancer women in the study aged between (45 – to less than 55) years, 80.0% were married, 63.3% lived in rural areas, 50.0% monthly income between (150 – less than 300) Egyptian pounds, 40.0% were illiterate, 36.7% of the sample had sever degree of stress at preoperative assessment while 56.7% had sever degree of stress at post operative assessment, there was negative statistically significant correlations between total stress and immune responses were T lymphocytes, CD4 helper, CD56 NK cell, and CD14 Monocytes in pre operative assessment. And T lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cell, and CD14 Monocytes in post operative assessment. Conclusions: the higher the degree of stress, the lower the values of T Lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cells, and CD14 Monocytes. Supporting cancer women during treatments through instructing their psychological and physical well-being. Recommendation: Further researches are needed with large sample size and control group.},
 year = {2015}
}

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TY  - JOUR
T1  - Impact of Stress on Immune Response of Breast Cancer Women After Mastectomy
AU  - Amal Mohamed Gamal
AU  - Sanaa Ibrahim Abd El-Gaffar
Y1  - 2015/07/04
PY  - 2015
N1  - https://doi.org/10.11648/j.ajns.20150404.16
DO  - 10.11648/j.ajns.20150404.16
T2  - American Journal of Nursing Science
JF  - American Journal of Nursing Science
JO  - American Journal of Nursing Science
SP  - 182
EP  - 189
PB  - Science Publishing Group
SN  - 2328-5753
UR  - https://doi.org/10.11648/j.ajns.20150404.16
AB  - Aim of the study was to determine the impact of stress on immune responses of breast cancer women after Mastectomy Materials and method: study was carried out on a convenient sample of 60 adult women diagnosed as breast cancer for stage II or III and scheduled for mastectomy at Oncology University Hospital of Menoufia A descriptive design was used. Two tools; were utilized to collect data related to this study were (1) Stress Assessment Scale, and (2) Immune Response Assessment Questionnaire. Results: revealed that 46.7% of breast cancer women in the study aged between (45 – to less than 55) years, 80.0% were married, 63.3% lived in rural areas, 50.0% monthly income between (150 – less than 300) Egyptian pounds, 40.0% were illiterate, 36.7% of the sample had sever degree of stress at preoperative assessment while 56.7% had sever degree of stress at post operative assessment, there was negative statistically significant correlations between total stress and immune responses were T lymphocytes, CD4 helper, CD56 NK cell, and CD14 Monocytes in pre operative assessment. And T lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cell, and CD14 Monocytes in post operative assessment. Conclusions: the higher the degree of stress, the lower the values of T Lymphocytes, CD4 helper, CD8 Cytotoxic, CD56 NK cells, and CD14 Monocytes. Supporting cancer women during treatments through instructing their psychological and physical well-being. Recommendation: Further researches are needed with large sample size and control group.
VL  - 4
IS  - 4
ER  -

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