Metabolic Syndrome in Obese Children over Five Years Old

Douaa Kharbotly; Ahmad Chreitah; Muhammed Imad Khayat

doi:doi:10.11648/j.ajp.20210703.14

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Metabolic Syndrome in Obese Children over Five Years Old

Douaa Kharbotly, Ahmad Chreitah, Muhammed Imad Khayat

Published in American Journal of Pediatrics (Volume 7, Issue 3)

Received: 9 June 2021 Accepted: 21 June 2021 Published: 9 July 2021

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Abstract

Background: Obesity is an important pediatric public health problem associated with increased risk of many complications in childhood and increased morbidity and mortality throughout adult life. Objectives: To assess the prevalence of Metabolic Syndrome in obese children and the relationship between Metabolic Syndrome and Body mass index (BMI), sex, age and family risk factors like obesity, hypertension, diabetes mellitus and cardiovascular disease. Materials and Methods: An analytic cross-sectional study was conducted in 178 overweight and obese children and adolescents aged 5-16 years old seen at the General Pediatric Clinic of the Tishreen University Hospital between March 2020 and February 2021. Weight, high, waist Circumference and blood pressure were measured. Blood samples were taken after 12 hours fasting and fasting blood glucose (FBG), total cholesterol (T Cho), high- density lipoprotein cholesterol (HDL) and low- density lipoprotein cholesterol (LDL) were measured. The Metabolic Syndrome MS was diagnosed based on pediatric and adolescent criteria adapted from the National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATP III) definition. Results: A total of 178 children, 82 males (46.1%) and 96 females (53.9%) with mean age 9.9±2.5 SD were in our study. Out of the 178 children, 62 (34.8%) were overweight, 101 (56.7%) obese and 15 (8.4%) were severe obese. According to the NCEP ATP III, (32.6%) out of (178) children were diagnosed with MS. Among children with MS, most components of MS were increased waist circumference WC (93.1%), increased TG (86.2%), reduced HDL (51.7%), increased BP (50%) and increased FBS (25.9%). MS prevalence was 12.9%, 36.6%, 86.7% in overweight, obese and severe obese children respectively

Published in	American Journal of Pediatrics (Volume 7, Issue 3)
DOI	10.11648/j.ajp.20210703.14
Page(s)	113-116
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Metabolic Syndrome, Obese, Overweight, Cardiovascular Disease

References

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[2]	Lee, K. (2008). The World Health Organization (WHO). Routledge.‏
[3]	St Geme, J. W., Blum, N. J., Shah, S. S., Tasker, R. C., & Wilson, K. M. (2020). Nelson textbook of pediatrics.
[4]	Klish, W. J., Kirkland, J., & Motil, K. (2015). Comorbidities and complications of obesity in children and adolescents. Up To Date [Internet].(Consultado noviembre 2009). Disponible en: http://www.uptodate.com/contents/comorbidities-and-complications-of-obesity-in-children-and-adolescents.
[5]	Mantzoros, C. (2005). Insulin resistance: Definition and clinical spectrum. Up to Date Online, 14, 1-5.
[6]	Mattoo, T. K. (2009). Definition and diagnosis of hypertension in children and adolescents. Up To Date.
[7]	DeBoer, M. D. (2019). Assessing and managing the metabolic syndrome in children and adolescents. Nutrients, 11 (8), 1788.
[8]	Özer, S., Kazanc, N. Ö., Sönmezgöz, E., Karaaslan, E., Altunta, B., & Kuyucu, Y. E. (2015). Higher HDL levels are a preventive factor for metabolic syndrome in obese Turkish children. Nutricion hospitalaria, 31 (1), 307-312.
[9]	Weiss, R., Dziura, J., Burgert, T. S., Tamborlane, W. V., Taksali, S. E., Yeckel, C. W.,... & Caprio, S. (2004). Obesity and the metabolic syndrome in children and adolescents. New England journal of medicine, 350 (23), 2362-2374.
[10]	Sangun, Ö., Dündar, B., Köşker, M., Pirgon, Ö., & Dündar, N. (2011). Prevalence of metabolic syndrome in obese children and adolescents using three different criteria and evaluation of risk factors. Journal of clinical research in pediatric endocrinology, 3 (2), 70.
[11]	Damiri, B., Alhala, A. A., Najjar, L., & Alqadome, S. (2018). Metabolic syndrome and its risk factors among overweight and obese Palestinian schoolchildren using IDF and NCEP-ATP/III definitions. Ann Clin Lab Res, 6 (3), 242.
[12]	Shah, S. M., Aziz, F., Al Meskari, F., Al Kaabi, J., Khan, U. I., & Jaacks, L. M. (2020). Metabolic syndrome among children aged 6 to 11 years, Al Ain, United Arab Emirates: Role of obesity. Pediatric diabetes, 21 (5), 735-742.
[13]	Medinaa, O. N., Arriagaa, R. V., Valverdeb, L. F., Lópeza, C. P. R., Skidmorec, O. M., Torresd, M. C. G.,... & Lópeza, S. G. (2015). Prevalence of metabolic syndrome in overweight and obese schoolchildren.
[14]	Rodrigues, L. G., Mattos, A. P., & Koifman, S. (2011). Prevalence of metabolic syndrome in overweight and obese outpatient children and adolescents: comparative analysis using different clinical definitions. Revista Paulista de Pediatria, 29, 178-185.‏

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APA Style

Douaa Kharbotly, Ahmad Chreitah, Muhammed Imad Khayat. (2021). Metabolic Syndrome in Obese Children over Five Years Old. American Journal of Pediatrics, 7(3), 113-116. https://doi.org/10.11648/j.ajp.20210703.14

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ACS Style

Douaa Kharbotly; Ahmad Chreitah; Muhammed Imad Khayat. Metabolic Syndrome in Obese Children over Five Years Old. Am. J. Pediatr. 2021, 7(3), 113-116. doi: 10.11648/j.ajp.20210703.14

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AMA Style

Douaa Kharbotly, Ahmad Chreitah, Muhammed Imad Khayat. Metabolic Syndrome in Obese Children over Five Years Old. Am J Pediatr. 2021;7(3):113-116. doi: 10.11648/j.ajp.20210703.14

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@article{10.11648/j.ajp.20210703.14,
  author = {Douaa Kharbotly and Ahmad Chreitah and Muhammed Imad Khayat},
  title = {Metabolic Syndrome in Obese Children over Five Years Old},
  journal = {American Journal of Pediatrics},
  volume = {7},
  number = {3},
  pages = {113-116},
  doi = {10.11648/j.ajp.20210703.14},
  url = {https://doi.org/10.11648/j.ajp.20210703.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20210703.14},
  abstract = {Background: Obesity is an important pediatric public health problem associated with increased risk of many complications in childhood and increased morbidity and mortality throughout adult life. Objectives: To assess the prevalence of Metabolic Syndrome in obese children and the relationship between Metabolic Syndrome and Body mass index (BMI), sex, age and family risk factors like obesity, hypertension, diabetes mellitus and cardiovascular disease. Materials and Methods: An analytic cross-sectional study was conducted in 178 overweight and obese children and adolescents aged 5-16 years old seen at the General Pediatric Clinic of the Tishreen University Hospital between March 2020 and February 2021. Weight, high, waist Circumference and blood pressure were measured. Blood samples were taken after 12 hours fasting and fasting blood glucose (FBG), total cholesterol (T Cho), high- density lipoprotein cholesterol (HDL) and low- density lipoprotein cholesterol (LDL) were measured. The Metabolic Syndrome MS was diagnosed based on pediatric and adolescent criteria adapted from the National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATP III) definition. Results: A total of 178 children, 82 males (46.1%) and 96 females (53.9%) with mean age 9.9±2.5 SD were in our study. Out of the 178 children, 62 (34.8%) were overweight, 101 (56.7%) obese and 15 (8.4%) were severe obese. According to the NCEP ATP III, (32.6%) out of (178) children were diagnosed with MS. Among children with MS, most components of MS were increased waist circumference WC (93.1%), increased TG (86.2%), reduced HDL (51.7%), increased BP (50%) and increased FBS (25.9%). MS prevalence was 12.9%, 36.6%, 86.7% in overweight, obese and severe obese children respectively},
 year = {2021}
}

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TY  - JOUR
T1  - Metabolic Syndrome in Obese Children over Five Years Old
AU  - Douaa Kharbotly
AU  - Ahmad Chreitah
AU  - Muhammed Imad Khayat
Y1  - 2021/07/09
PY  - 2021
N1  - https://doi.org/10.11648/j.ajp.20210703.14
DO  - 10.11648/j.ajp.20210703.14
T2  - American Journal of Pediatrics
JF  - American Journal of Pediatrics
JO  - American Journal of Pediatrics
SP  - 113
EP  - 116
PB  - Science Publishing Group
SN  - 2472-0909
UR  - https://doi.org/10.11648/j.ajp.20210703.14
AB  - Background: Obesity is an important pediatric public health problem associated with increased risk of many complications in childhood and increased morbidity and mortality throughout adult life. Objectives: To assess the prevalence of Metabolic Syndrome in obese children and the relationship between Metabolic Syndrome and Body mass index (BMI), sex, age and family risk factors like obesity, hypertension, diabetes mellitus and cardiovascular disease. Materials and Methods: An analytic cross-sectional study was conducted in 178 overweight and obese children and adolescents aged 5-16 years old seen at the General Pediatric Clinic of the Tishreen University Hospital between March 2020 and February 2021. Weight, high, waist Circumference and blood pressure were measured. Blood samples were taken after 12 hours fasting and fasting blood glucose (FBG), total cholesterol (T Cho), high- density lipoprotein cholesterol (HDL) and low- density lipoprotein cholesterol (LDL) were measured. The Metabolic Syndrome MS was diagnosed based on pediatric and adolescent criteria adapted from the National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATP III) definition. Results: A total of 178 children, 82 males (46.1%) and 96 females (53.9%) with mean age 9.9±2.5 SD were in our study. Out of the 178 children, 62 (34.8%) were overweight, 101 (56.7%) obese and 15 (8.4%) were severe obese. According to the NCEP ATP III, (32.6%) out of (178) children were diagnosed with MS. Among children with MS, most components of MS were increased waist circumference WC (93.1%), increased TG (86.2%), reduced HDL (51.7%), increased BP (50%) and increased FBS (25.9%). MS prevalence was 12.9%, 36.6%, 86.7% in overweight, obese and severe obese children respectively
VL  - 7
IS  - 3
ER  -

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Author Information

Douaa Kharbotly

Department of Pediatrics, Faculty of Medicine, Tishreen University Hospital, Lattakia, Syria
Ahmad Chreitah

Department of Pediatrics, Faculty of Medicine, Tishreen University Hospital, Lattakia, Syria
Muhammed Imad Khayat

Department of Laboratory Medicine, Tishreen University Hospital, Lattakia, Syria

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APA Style

Douaa Kharbotly, Ahmad Chreitah, Muhammed Imad Khayat. (2021). Metabolic Syndrome in Obese Children over Five Years Old. American Journal of Pediatrics, 7(3), 113-116. https://doi.org/10.11648/j.ajp.20210703.14

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ACS Style

Douaa Kharbotly; Ahmad Chreitah; Muhammed Imad Khayat. Metabolic Syndrome in Obese Children over Five Years Old. Am. J. Pediatr. 2021, 7(3), 113-116. doi: 10.11648/j.ajp.20210703.14

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AMA Style

Douaa Kharbotly, Ahmad Chreitah, Muhammed Imad Khayat. Metabolic Syndrome in Obese Children over Five Years Old. Am J Pediatr. 2021;7(3):113-116. doi: 10.11648/j.ajp.20210703.14

Copy | Download

@article{10.11648/j.ajp.20210703.14,
  author = {Douaa Kharbotly and Ahmad Chreitah and Muhammed Imad Khayat},
  title = {Metabolic Syndrome in Obese Children over Five Years Old},
  journal = {American Journal of Pediatrics},
  volume = {7},
  number = {3},
  pages = {113-116},
  doi = {10.11648/j.ajp.20210703.14},
  url = {https://doi.org/10.11648/j.ajp.20210703.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20210703.14},
  abstract = {Background: Obesity is an important pediatric public health problem associated with increased risk of many complications in childhood and increased morbidity and mortality throughout adult life. Objectives: To assess the prevalence of Metabolic Syndrome in obese children and the relationship between Metabolic Syndrome and Body mass index (BMI), sex, age and family risk factors like obesity, hypertension, diabetes mellitus and cardiovascular disease. Materials and Methods: An analytic cross-sectional study was conducted in 178 overweight and obese children and adolescents aged 5-16 years old seen at the General Pediatric Clinic of the Tishreen University Hospital between March 2020 and February 2021. Weight, high, waist Circumference and blood pressure were measured. Blood samples were taken after 12 hours fasting and fasting blood glucose (FBG), total cholesterol (T Cho), high- density lipoprotein cholesterol (HDL) and low- density lipoprotein cholesterol (LDL) were measured. The Metabolic Syndrome MS was diagnosed based on pediatric and adolescent criteria adapted from the National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATP III) definition. Results: A total of 178 children, 82 males (46.1%) and 96 females (53.9%) with mean age 9.9±2.5 SD were in our study. Out of the 178 children, 62 (34.8%) were overweight, 101 (56.7%) obese and 15 (8.4%) were severe obese. According to the NCEP ATP III, (32.6%) out of (178) children were diagnosed with MS. Among children with MS, most components of MS were increased waist circumference WC (93.1%), increased TG (86.2%), reduced HDL (51.7%), increased BP (50%) and increased FBS (25.9%). MS prevalence was 12.9%, 36.6%, 86.7% in overweight, obese and severe obese children respectively},
 year = {2021}
}

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TY  - JOUR
T1  - Metabolic Syndrome in Obese Children over Five Years Old
AU  - Douaa Kharbotly
AU  - Ahmad Chreitah
AU  - Muhammed Imad Khayat
Y1  - 2021/07/09
PY  - 2021
N1  - https://doi.org/10.11648/j.ajp.20210703.14
DO  - 10.11648/j.ajp.20210703.14
T2  - American Journal of Pediatrics
JF  - American Journal of Pediatrics
JO  - American Journal of Pediatrics
SP  - 113
EP  - 116
PB  - Science Publishing Group
SN  - 2472-0909
UR  - https://doi.org/10.11648/j.ajp.20210703.14
AB  - Background: Obesity is an important pediatric public health problem associated with increased risk of many complications in childhood and increased morbidity and mortality throughout adult life. Objectives: To assess the prevalence of Metabolic Syndrome in obese children and the relationship between Metabolic Syndrome and Body mass index (BMI), sex, age and family risk factors like obesity, hypertension, diabetes mellitus and cardiovascular disease. Materials and Methods: An analytic cross-sectional study was conducted in 178 overweight and obese children and adolescents aged 5-16 years old seen at the General Pediatric Clinic of the Tishreen University Hospital between March 2020 and February 2021. Weight, high, waist Circumference and blood pressure were measured. Blood samples were taken after 12 hours fasting and fasting blood glucose (FBG), total cholesterol (T Cho), high- density lipoprotein cholesterol (HDL) and low- density lipoprotein cholesterol (LDL) were measured. The Metabolic Syndrome MS was diagnosed based on pediatric and adolescent criteria adapted from the National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATP III) definition. Results: A total of 178 children, 82 males (46.1%) and 96 females (53.9%) with mean age 9.9±2.5 SD were in our study. Out of the 178 children, 62 (34.8%) were overweight, 101 (56.7%) obese and 15 (8.4%) were severe obese. According to the NCEP ATP III, (32.6%) out of (178) children were diagnosed with MS. Among children with MS, most components of MS were increased waist circumference WC (93.1%), increased TG (86.2%), reduced HDL (51.7%), increased BP (50%) and increased FBS (25.9%). MS prevalence was 12.9%, 36.6%, 86.7% in overweight, obese and severe obese children respectively
VL  - 7
IS  - 3
ER  -

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