Background: Hantaviruses are enzootic haemorrhagic fever viruses whose transmission to humans can cause serious illness with mortality rates ranging from 12% to 40%. Objective: This study aimed to estimate the seroprevalence of IgG antibodies against hantaviruses in the Conakry region. Methods: This was a cross-sectional study of suspected haemorrhagic fever cases. Blood samples were analysed at the Guinea Virology Research Center, Conakry, Republic of Guinea. The indirect enzyme-linked immunosorbent assay (Euro-Immun, vector-best, Russia) was used to detect the presence of specific IgG antibodies to hantaviruses according to the manufacturer's instructions. Results: A total of 368 suspected cases of haemorrhagic fever were reported between 2021 and 2022 in public health facilities in Conakry. The seroprevalence of IgG in patients was 8.7% (95% CI: 6.1-12.0). Patients under 30 years of age were the group most affected (14.9%). The seroprevalence of hantaviruses was significantly higher in trades worker (16.0%) than in other socio-professional categories (p<0.001). Patients with fever associated with anorexia and cough had a hantavirus IgG seroprevalence of 45.5% and 28.9% respectively. Conclusion: This study provided serological evidence of hantavirus circulation in the Conakry region. Active surveillance of hantaviruses, including molecular biology and serotyping, would be necessary to improve our understanding of the ecology of circulating hantavirus strains.
| Published in | Central African Journal of Public Health (Volume 9, Issue 6) |
| DOI | 10.11648/j.cajph.20230906.14 |
| Page(s) | 182-186 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Guinea, Hantavirus, Hemorrhagic Fevers, Serological
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APA Style
Traoré, S., Talassone Bangoura, S., Camara, A., Youla, Y., Ibrahim, N., et al. (2023). Serological Evidence of Hantavirus Infection in Suspected Cases of Viral Haemorrhagic Fever in Conakry, Guinea. Central African Journal of Public Health, 9(6), 182-186. https://doi.org/10.11648/j.cajph.20230906.14
ACS Style
Traoré, S.; Talassone Bangoura, S.; Camara, A.; Youla, Y.; Ibrahim, N., et al. Serological Evidence of Hantavirus Infection in Suspected Cases of Viral Haemorrhagic Fever in Conakry, Guinea. Cent. Afr. J. Public Health 2023, 9(6), 182-186. doi: 10.11648/j.cajph.20230906.14
AMA Style
Traoré S, Talassone Bangoura S, Camara A, Youla Y, Ibrahim N, et al. Serological Evidence of Hantavirus Infection in Suspected Cases of Viral Haemorrhagic Fever in Conakry, Guinea. Cent Afr J Public Health. 2023;9(6):182-186. doi: 10.11648/j.cajph.20230906.14
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author = {Sékou Traoré and Salifou Talassone Bangoura and Alimou Camara and Yamoussa Youla and Nourdine Ibrahim and Maladho Diaby and Kadio Jean-Jacques Olivier Kadio and Saidouba Cherif Camara and Tanou Valdez Bah and Foromo Timothée Beavogui and Sidikiba Sidibé and Abdoulaye Touré and Sanaba Boumbaly},
title = {Serological Evidence of Hantavirus Infection in Suspected Cases of Viral Haemorrhagic Fever in Conakry, Guinea},
journal = {Central African Journal of Public Health},
volume = {9},
number = {6},
pages = {182-186},
doi = {10.11648/j.cajph.20230906.14},
url = {https://doi.org/10.11648/j.cajph.20230906.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20230906.14},
abstract = {Background: Hantaviruses are enzootic haemorrhagic fever viruses whose transmission to humans can cause serious illness with mortality rates ranging from 12% to 40%. Objective: This study aimed to estimate the seroprevalence of IgG antibodies against hantaviruses in the Conakry region. Methods: This was a cross-sectional study of suspected haemorrhagic fever cases. Blood samples were analysed at the Guinea Virology Research Center, Conakry, Republic of Guinea. The indirect enzyme-linked immunosorbent assay (Euro-Immun, vector-best, Russia) was used to detect the presence of specific IgG antibodies to hantaviruses according to the manufacturer's instructions. Results: A total of 368 suspected cases of haemorrhagic fever were reported between 2021 and 2022 in public health facilities in Conakry. The seroprevalence of IgG in patients was 8.7% (95% CI: 6.1-12.0). Patients under 30 years of age were the group most affected (14.9%). The seroprevalence of hantaviruses was significantly higher in trades worker (16.0%) than in other socio-professional categories (p<0.001). Patients with fever associated with anorexia and cough had a hantavirus IgG seroprevalence of 45.5% and 28.9% respectively. Conclusion: This study provided serological evidence of hantavirus circulation in the Conakry region. Active surveillance of hantaviruses, including molecular biology and serotyping, would be necessary to improve our understanding of the ecology of circulating hantavirus strains.
},
year = {2023}
}
TY - JOUR T1 - Serological Evidence of Hantavirus Infection in Suspected Cases of Viral Haemorrhagic Fever in Conakry, Guinea AU - Sékou Traoré AU - Salifou Talassone Bangoura AU - Alimou Camara AU - Yamoussa Youla AU - Nourdine Ibrahim AU - Maladho Diaby AU - Kadio Jean-Jacques Olivier Kadio AU - Saidouba Cherif Camara AU - Tanou Valdez Bah AU - Foromo Timothée Beavogui AU - Sidikiba Sidibé AU - Abdoulaye Touré AU - Sanaba Boumbaly Y1 - 2023/12/28 PY - 2023 N1 - https://doi.org/10.11648/j.cajph.20230906.14 DO - 10.11648/j.cajph.20230906.14 T2 - Central African Journal of Public Health JF - Central African Journal of Public Health JO - Central African Journal of Public Health SP - 182 EP - 186 PB - Science Publishing Group SN - 2575-5781 UR - https://doi.org/10.11648/j.cajph.20230906.14 AB - Background: Hantaviruses are enzootic haemorrhagic fever viruses whose transmission to humans can cause serious illness with mortality rates ranging from 12% to 40%. Objective: This study aimed to estimate the seroprevalence of IgG antibodies against hantaviruses in the Conakry region. Methods: This was a cross-sectional study of suspected haemorrhagic fever cases. Blood samples were analysed at the Guinea Virology Research Center, Conakry, Republic of Guinea. The indirect enzyme-linked immunosorbent assay (Euro-Immun, vector-best, Russia) was used to detect the presence of specific IgG antibodies to hantaviruses according to the manufacturer's instructions. Results: A total of 368 suspected cases of haemorrhagic fever were reported between 2021 and 2022 in public health facilities in Conakry. The seroprevalence of IgG in patients was 8.7% (95% CI: 6.1-12.0). Patients under 30 years of age were the group most affected (14.9%). The seroprevalence of hantaviruses was significantly higher in trades worker (16.0%) than in other socio-professional categories (p<0.001). Patients with fever associated with anorexia and cough had a hantavirus IgG seroprevalence of 45.5% and 28.9% respectively. Conclusion: This study provided serological evidence of hantavirus circulation in the Conakry region. Active surveillance of hantaviruses, including molecular biology and serotyping, would be necessary to improve our understanding of the ecology of circulating hantavirus strains. VL - 9 IS - 6 ER -
Department of Pharmaceutical and Biological Sciences, Gamal Abdel Nasser University, Conakry, Republic of Guinea; Guinea Center for Research and Training in Infectious Diseases (CERFIG), Gamal Abdel Nasser University, Conakry, Republic of Guinea
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