@article{10.11648/j.ejcbs.20230902.11,
  author = {Uhiara Ngozi Sunday and Ohanwe Cyprian Nnanwa and Clement Ezeaku Anikezie and Adesanya Oluwatosin Dorothy and Samuel Emmanuel and Jacob Gabriel Anayo and Uhiara Nkolika Leontina and Yelmi Bitrus},
  title = {Impact of Some Antioxidants (Allicin-AL, Saponin -SN, Carotenes-CN, Euginol, Vitamins C and E) Rich Vegetables on Common Metabolic Lipid Parameters},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {9},
  number = {2},
  pages = {18-21},
  doi = {10.11648/j.ejcbs.20230902.11},
  url = {https://doi.org/10.11648/j.ejcbs.20230902.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20230902.11},
  abstract = {Attempt at comparing the impact of some antioxidant – rich vegetables (singularly or combinations) on common atherosclerosis lipid parameters. The experiments were conducted in three phases. Phase (A) Five (5) ml each of aqueous extract of (i) fresh (ocimum gratissimum) scent leaf (ii) bitter leafs (vernonia amygdalina) (iii) 2.5ml each of bitter leaf and scent leaf mix; was mixed thoroughly with 100g of normal rat feed. Phase (B) five (5) ml each of aqueous extract of (i) utazi (gongronema latifolium) leafs (ii) aloevera leafs (iii) 2.5g each of utazi and aloe vera mix; was mixed into 100g normal rat feed. The third phase involved 5g each of (i) fresh (docasus carota) carrot (ii) tomato (solanum lycopersicum) (iii) carrot and tomato mix. Each of the nine (9) feed samples (3 from each phase) were separately feed to a set of three albino rats for 21 days; so was 100% (control) rat feed and garlic supplemented (5g crushed garlic, blended with 100g) rat feed. The weights, feed intake and weight of droppings of the rats were recorded at three days’ intervals during experimental feeding. The blood samples of the rats were harvested at the end of the 21 days and lipid analysis carried out on them. The rat feeds supplemented with utazi, nchanwu and aloevera leafs’ water extracts respectively scored 2.7, 3.7 and 2.9mmol/ml respectively regarding total cholesterol; all significantly lower than the normal range of 5.17mmol/ml (p ≤ 0.05). With respect to triglycerides, 1.9, 1.9 and 1.7 respectively scored by Utazi, aloe vera and bitter leaf supplemented feeds were all close to the acceptable range of 0.7 – 1.7Mmol/ml. The combined effect of utazi and Aloe vera on HDL, was significantly lowering (0.5Mmol/ml) compared to 1.5 and 1.6 Mmol/ml of individual Utazi and Aloe vera respectively. The three feed samples (Utazi/aleovera, tomatoe/carrot and bitter leaf/scent leaf) that combined two vegetables rich in same or different antioxidants, all reported lower weight gains with collaborating lower scores in lipid parameters; clue for broad spectrum anti atherosclerosis therapy preparation.},
 year = {2023}
}

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TY  - JOUR
T1  - Impact of Some Antioxidants (Allicin-AL, Saponin -SN, Carotenes-CN, Euginol, Vitamins C and E) Rich Vegetables on Common Metabolic Lipid Parameters
AU  - Uhiara Ngozi Sunday
AU  - Ohanwe Cyprian Nnanwa
AU  - Clement Ezeaku Anikezie
AU  - Adesanya Oluwatosin Dorothy
AU  - Samuel Emmanuel
AU  - Jacob Gabriel Anayo
AU  - Uhiara Nkolika Leontina
AU  - Yelmi Bitrus
Y1  - 2023/04/11
PY  - 2023
N1  - https://doi.org/10.11648/j.ejcbs.20230902.11
DO  - 10.11648/j.ejcbs.20230902.11
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 18
EP  - 21
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20230902.11
AB  - Attempt at comparing the impact of some antioxidant – rich vegetables (singularly or combinations) on common atherosclerosis lipid parameters. The experiments were conducted in three phases. Phase (A) Five (5) ml each of aqueous extract of (i) fresh (ocimum gratissimum) scent leaf (ii) bitter leafs (vernonia amygdalina) (iii) 2.5ml each of bitter leaf and scent leaf mix; was mixed thoroughly with 100g of normal rat feed. Phase (B) five (5) ml each of aqueous extract of (i) utazi (gongronema latifolium) leafs (ii) aloevera leafs (iii) 2.5g each of utazi and aloe vera mix; was mixed into 100g normal rat feed. The third phase involved 5g each of (i) fresh (docasus carota) carrot (ii) tomato (solanum lycopersicum) (iii) carrot and tomato mix. Each of the nine (9) feed samples (3 from each phase) were separately feed to a set of three albino rats for 21 days; so was 100% (control) rat feed and garlic supplemented (5g crushed garlic, blended with 100g) rat feed. The weights, feed intake and weight of droppings of the rats were recorded at three days’ intervals during experimental feeding. The blood samples of the rats were harvested at the end of the 21 days and lipid analysis carried out on them. The rat feeds supplemented with utazi, nchanwu and aloevera leafs’ water extracts respectively scored 2.7, 3.7 and 2.9mmol/ml respectively regarding total cholesterol; all significantly lower than the normal range of 5.17mmol/ml (p ≤ 0.05). With respect to triglycerides, 1.9, 1.9 and 1.7 respectively scored by Utazi, aloe vera and bitter leaf supplemented feeds were all close to the acceptable range of 0.7 – 1.7Mmol/ml. The combined effect of utazi and Aloe vera on HDL, was significantly lowering (0.5Mmol/ml) compared to 1.5 and 1.6 Mmol/ml of individual Utazi and Aloe vera respectively. The three feed samples (Utazi/aleovera, tomatoe/carrot and bitter leaf/scent leaf) that combined two vegetables rich in same or different antioxidants, all reported lower weight gains with collaborating lower scores in lipid parameters; clue for broad spectrum anti atherosclerosis therapy preparation.
VL  - 9
IS  - 2
ER  - 

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