Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B

Yi Na; Siwen Wei; Xiaoran Wang; Yi Wang; Ruilian Ma; Lidao Bao

doi:doi:10.11648/j.ijbse.20170503.12

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Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B

Yi Na, Siwen Wei, Xiaoran Wang, Yi Wang, Ruilian Ma, Lidao Bao

Published in International Journal of Biomedical Science and Engineering (Volume 5, Issue 3)

Received: 6 June 2017 Accepted: Published: 6 June 2017

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Abstract

To study the clinical effects of Safflower Pill of Dedu Seven Medicinal Herbs combined with Adefovir Dipivoxil on liver fibrosis resulting from chronic viral hepatitis B.116 patients with chronic hepatitis B fibrosis were randomly divided into two groups (n=58 for each group): treatment group (Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil) and control group (Adefovir Dipivoxil) (n=58) for clinical observation of 24 weeks. After 24 weeks, the effective rates were 93.10% and 81.03% in the treatment group and control group respectively; the indexes of liver function, liver fibrosis and radiographic indexes of the patients in both groups were significantly decreased (P <0.05 or P <0.01); The differences between the two groups were statistically significant (P <0.05). The effect of Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil for the treatment of chronic hepatitis B fibrosis is more effective than that of Adefovir Dipivoxil alone.

Published in	International Journal of Biomedical Science and Engineering (Volume 5, Issue 3)
DOI	10.11648/j.ijbse.20170503.12
Page(s)	24-28
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Adefovir Dipivoxil, Chronic Viral Hepatitis B, Liver Fibrosis, Safflower Pill of Seven Medicinal Herbs

References

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[17]	Xie DY, Lin BL, Xu QH, Chen YM, Lu WL, Li JG, et al. [The predictive value of ALT, HBeAg and HBV DNA levels at baseline and the degree of HBV suppression at week 12 adefovir dipivoxil treatment to the efficacy of it at week 52 in patients with HBeAg-positive chronic hepatitis B]. Zhonghua Gan Zang Bing Za Zhi 2008;16:341-4.
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APA Style

Yi Na, Siwen Wei, Xiaoran Wang, Yi Wang, Ruilian Ma, et al. (2017). Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B. International Journal of Biomedical Science and Engineering, 5(3), 24-28. https://doi.org/10.11648/j.ijbse.20170503.12

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ACS Style

Yi Na; Siwen Wei; Xiaoran Wang; Yi Wang; Ruilian Ma, et al. Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B. Int. J. Biomed. Sci. Eng. 2017, 5(3), 24-28. doi: 10.11648/j.ijbse.20170503.12

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AMA Style

Yi Na, Siwen Wei, Xiaoran Wang, Yi Wang, Ruilian Ma, et al. Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B. Int J Biomed Sci Eng. 2017;5(3):24-28. doi: 10.11648/j.ijbse.20170503.12

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@article{10.11648/j.ijbse.20170503.12,
  author = {Yi Na and Siwen Wei and Xiaoran Wang and Yi Wang and Ruilian Ma and Lidao Bao},
  title = {Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B},
  journal = {International Journal of Biomedical Science and Engineering},
  volume = {5},
  number = {3},
  pages = {24-28},
  doi = {10.11648/j.ijbse.20170503.12},
  url = {https://doi.org/10.11648/j.ijbse.20170503.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbse.20170503.12},
  abstract = {To study the clinical effects of Safflower Pill of Dedu Seven Medicinal Herbs combined with Adefovir Dipivoxil on liver fibrosis resulting from chronic viral hepatitis B.116 patients with chronic hepatitis B fibrosis were randomly divided into two groups (n=58 for each group): treatment group (Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil) and control group (Adefovir Dipivoxil) (n=58) for clinical observation of 24 weeks. After 24 weeks, the effective rates were 93.10% and 81.03% in the treatment group and control group respectively; the indexes of liver function, liver fibrosis and radiographic indexes of the patients in both groups were significantly decreased (P <0.05 or P <0.01); The differences between the two groups were statistically significant (P <0.05). The effect of Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil for the treatment of chronic hepatitis B fibrosis is more effective than that of Adefovir Dipivoxil alone.},
 year = {2017}
}

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TY  - JOUR
T1  - Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B
AU  - Yi Na
AU  - Siwen Wei
AU  - Xiaoran Wang
AU  - Yi Wang
AU  - Ruilian Ma
AU  - Lidao Bao
Y1  - 2017/06/06
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbse.20170503.12
DO  - 10.11648/j.ijbse.20170503.12
T2  - International Journal of Biomedical Science and Engineering
JF  - International Journal of Biomedical Science and Engineering
JO  - International Journal of Biomedical Science and Engineering
SP  - 24
EP  - 28
PB  - Science Publishing Group
SN  - 2376-7235
UR  - https://doi.org/10.11648/j.ijbse.20170503.12
AB  - To study the clinical effects of Safflower Pill of Dedu Seven Medicinal Herbs combined with Adefovir Dipivoxil on liver fibrosis resulting from chronic viral hepatitis B.116 patients with chronic hepatitis B fibrosis were randomly divided into two groups (n=58 for each group): treatment group (Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil) and control group (Adefovir Dipivoxil) (n=58) for clinical observation of 24 weeks. After 24 weeks, the effective rates were 93.10% and 81.03% in the treatment group and control group respectively; the indexes of liver function, liver fibrosis and radiographic indexes of the patients in both groups were significantly decreased (P <0.05 or P <0.01); The differences between the two groups were statistically significant (P <0.05). The effect of Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil for the treatment of chronic hepatitis B fibrosis is more effective than that of Adefovir Dipivoxil alone.
VL  - 5
IS  - 3
ER  -

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Author Information

Yi Na

College of Pharmacy, Inner Mongolia Medical University, Hohhot, P. R. China
Siwen Wei

College of Pharmacy, Inner Mongolia Medical University, Hohhot, P. R. China
Xiaoran Wang

College of Pharmacy, Inner Mongolia Medical University, Hohhot, P. R. China
Yi Wang

Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, P. R. China
Ruilian Ma

Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, P. R. China
Lidao Bao

Department of Pharmacy, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, P. R. China

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Plain Text BibTeX RIS

APA Style

Yi Na, Siwen Wei, Xiaoran Wang, Yi Wang, Ruilian Ma, et al. (2017). Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B. International Journal of Biomedical Science and Engineering, 5(3), 24-28. https://doi.org/10.11648/j.ijbse.20170503.12

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ACS Style

Yi Na; Siwen Wei; Xiaoran Wang; Yi Wang; Ruilian Ma, et al. Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B. Int. J. Biomed. Sci. Eng. 2017, 5(3), 24-28. doi: 10.11648/j.ijbse.20170503.12

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AMA Style

Yi Na, Siwen Wei, Xiaoran Wang, Yi Wang, Ruilian Ma, et al. Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B. Int J Biomed Sci Eng. 2017;5(3):24-28. doi: 10.11648/j.ijbse.20170503.12

Copy | Download

@article{10.11648/j.ijbse.20170503.12,
  author = {Yi Na and Siwen Wei and Xiaoran Wang and Yi Wang and Ruilian Ma and Lidao Bao},
  title = {Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B},
  journal = {International Journal of Biomedical Science and Engineering},
  volume = {5},
  number = {3},
  pages = {24-28},
  doi = {10.11648/j.ijbse.20170503.12},
  url = {https://doi.org/10.11648/j.ijbse.20170503.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbse.20170503.12},
  abstract = {To study the clinical effects of Safflower Pill of Dedu Seven Medicinal Herbs combined with Adefovir Dipivoxil on liver fibrosis resulting from chronic viral hepatitis B.116 patients with chronic hepatitis B fibrosis were randomly divided into two groups (n=58 for each group): treatment group (Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil) and control group (Adefovir Dipivoxil) (n=58) for clinical observation of 24 weeks. After 24 weeks, the effective rates were 93.10% and 81.03% in the treatment group and control group respectively; the indexes of liver function, liver fibrosis and radiographic indexes of the patients in both groups were significantly decreased (P <0.05 or P <0.01); The differences between the two groups were statistically significant (P <0.05). The effect of Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil for the treatment of chronic hepatitis B fibrosis is more effective than that of Adefovir Dipivoxil alone.},
 year = {2017}
}

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TY  - JOUR
T1  - Clinical Effects of Safflower Pill of Dedu Seven Medicinal Herbs Plus Adefovir Dipivoxil on Liver Fibrosis Resulting from Chronic Viral Hepatitis B
AU  - Yi Na
AU  - Siwen Wei
AU  - Xiaoran Wang
AU  - Yi Wang
AU  - Ruilian Ma
AU  - Lidao Bao
Y1  - 2017/06/06
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbse.20170503.12
DO  - 10.11648/j.ijbse.20170503.12
T2  - International Journal of Biomedical Science and Engineering
JF  - International Journal of Biomedical Science and Engineering
JO  - International Journal of Biomedical Science and Engineering
SP  - 24
EP  - 28
PB  - Science Publishing Group
SN  - 2376-7235
UR  - https://doi.org/10.11648/j.ijbse.20170503.12
AB  - To study the clinical effects of Safflower Pill of Dedu Seven Medicinal Herbs combined with Adefovir Dipivoxil on liver fibrosis resulting from chronic viral hepatitis B.116 patients with chronic hepatitis B fibrosis were randomly divided into two groups (n=58 for each group): treatment group (Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil) and control group (Adefovir Dipivoxil) (n=58) for clinical observation of 24 weeks. After 24 weeks, the effective rates were 93.10% and 81.03% in the treatment group and control group respectively; the indexes of liver function, liver fibrosis and radiographic indexes of the patients in both groups were significantly decreased (P <0.05 or P <0.01); The differences between the two groups were statistically significant (P <0.05). The effect of Safflower Pill of Seven Medicinal Herbs combined with Adefovir Dipivoxil for the treatment of chronic hepatitis B fibrosis is more effective than that of Adefovir Dipivoxil alone.
VL  - 5
IS  - 3
ER  -

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