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Wavelength Effect in Laser Therapy of Diabetic Rats on Oxidants: AGEs, AOPP, ox-LDL Levels

Received: 26 March 2020     Accepted: 21 April 2020     Published: 28 May 2020
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Abstract

In Low-Level Laser Therapy (LLLT) choosing the proper laser wavelength is extremely important. In this article, we have investigated the effects of four different laser wavelengths on oxidant parameters (AGE, AOPP, and ox-LDL) levels in diabetic Wistar rats experimentally. At first, 24 rats were divided into six equal groups. Except for the none diabetic control group, the other five groups received streptozotocin (STZ) injection to induce diabetes. Four groups of diabetic rats were then irradiated by four different laser wavelengths IR (808nm), Red (638nm), Green (532nm) and Blue (450nm). The last group which did not receive any irradiation is named non-irradiated diabetic control group. Laser therapies were performed Intravenously through an animal's caudal vein by a fiber Optics. Finally, the levels of oxidant parameters in rat's blood samples of each group were discussed. Results show a decrease in oxidants levels in all four irradiated groups of rats relative to the non-irradiated diabetic control group. More importantly, shorter wavelengths affect more efficient than longer wavelengths on reducing the oxidants levels with constant Laser energy. As a result, we conclude that laser with shorter wavelength e.g. Blue is more effective than longer wavelengths e.g. IR or Red, in reducing the oxidant parameters (AGE, AOPP, and ox-LDL) levels in Intravenous LLLT.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 6, Issue 2)
DOI 10.11648/j.ijcems.20200602.11
Page(s) 17-24
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Laser Therapy, Diabetes, Oxidants, AGEs, AOPP, Ox-LDL

References
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Cite This Article
  • APA Style

    Hossein Mirmiranpour, Ahmad Amjadi, Salile Khandani, Yasaman Shafaee, Seyed Omid Sobhani. (2020). Wavelength Effect in Laser Therapy of Diabetic Rats on Oxidants: AGEs, AOPP, ox-LDL Levels. International Journal of Clinical and Experimental Medical Sciences, 6(2), 17-24. https://doi.org/10.11648/j.ijcems.20200602.11

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    ACS Style

    Hossein Mirmiranpour; Ahmad Amjadi; Salile Khandani; Yasaman Shafaee; Seyed Omid Sobhani. Wavelength Effect in Laser Therapy of Diabetic Rats on Oxidants: AGEs, AOPP, ox-LDL Levels. Int. J. Clin. Exp. Med. Sci. 2020, 6(2), 17-24. doi: 10.11648/j.ijcems.20200602.11

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    AMA Style

    Hossein Mirmiranpour, Ahmad Amjadi, Salile Khandani, Yasaman Shafaee, Seyed Omid Sobhani. Wavelength Effect in Laser Therapy of Diabetic Rats on Oxidants: AGEs, AOPP, ox-LDL Levels. Int J Clin Exp Med Sci. 2020;6(2):17-24. doi: 10.11648/j.ijcems.20200602.11

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  • @article{10.11648/j.ijcems.20200602.11,
      author = {Hossein Mirmiranpour and Ahmad Amjadi and Salile Khandani and Yasaman Shafaee and Seyed Omid Sobhani},
      title = {Wavelength Effect in Laser Therapy of Diabetic Rats on Oxidants: AGEs, AOPP, ox-LDL Levels},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {6},
      number = {2},
      pages = {17-24},
      doi = {10.11648/j.ijcems.20200602.11},
      url = {https://doi.org/10.11648/j.ijcems.20200602.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20200602.11},
      abstract = {In Low-Level Laser Therapy (LLLT) choosing the proper laser wavelength is extremely important. In this article, we have investigated the effects of four different laser wavelengths on oxidant parameters (AGE, AOPP, and ox-LDL) levels in diabetic Wistar rats experimentally. At first, 24 rats were divided into six equal groups. Except for the none diabetic control group, the other five groups received streptozotocin (STZ) injection to induce diabetes. Four groups of diabetic rats were then irradiated by four different laser wavelengths IR (808nm), Red (638nm), Green (532nm) and Blue (450nm). The last group which did not receive any irradiation is named non-irradiated diabetic control group. Laser therapies were performed Intravenously through an animal's caudal vein by a fiber Optics. Finally, the levels of oxidant parameters in rat's blood samples of each group were discussed. Results show a decrease in oxidants levels in all four irradiated groups of rats relative to the non-irradiated diabetic control group. More importantly, shorter wavelengths affect more efficient than longer wavelengths on reducing the oxidants levels with constant Laser energy. As a result, we conclude that laser with shorter wavelength e.g. Blue is more effective than longer wavelengths e.g. IR or Red, in reducing the oxidant parameters (AGE, AOPP, and ox-LDL) levels in Intravenous LLLT.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Wavelength Effect in Laser Therapy of Diabetic Rats on Oxidants: AGEs, AOPP, ox-LDL Levels
    AU  - Hossein Mirmiranpour
    AU  - Ahmad Amjadi
    AU  - Salile Khandani
    AU  - Yasaman Shafaee
    AU  - Seyed Omid Sobhani
    Y1  - 2020/05/28
    PY  - 2020
    N1  - https://doi.org/10.11648/j.ijcems.20200602.11
    DO  - 10.11648/j.ijcems.20200602.11
    T2  - International Journal of Clinical and Experimental Medical Sciences
    JF  - International Journal of Clinical and Experimental Medical Sciences
    JO  - International Journal of Clinical and Experimental Medical Sciences
    SP  - 17
    EP  - 24
    PB  - Science Publishing Group
    SN  - 2469-8032
    UR  - https://doi.org/10.11648/j.ijcems.20200602.11
    AB  - In Low-Level Laser Therapy (LLLT) choosing the proper laser wavelength is extremely important. In this article, we have investigated the effects of four different laser wavelengths on oxidant parameters (AGE, AOPP, and ox-LDL) levels in diabetic Wistar rats experimentally. At first, 24 rats were divided into six equal groups. Except for the none diabetic control group, the other five groups received streptozotocin (STZ) injection to induce diabetes. Four groups of diabetic rats were then irradiated by four different laser wavelengths IR (808nm), Red (638nm), Green (532nm) and Blue (450nm). The last group which did not receive any irradiation is named non-irradiated diabetic control group. Laser therapies were performed Intravenously through an animal's caudal vein by a fiber Optics. Finally, the levels of oxidant parameters in rat's blood samples of each group were discussed. Results show a decrease in oxidants levels in all four irradiated groups of rats relative to the non-irradiated diabetic control group. More importantly, shorter wavelengths affect more efficient than longer wavelengths on reducing the oxidants levels with constant Laser energy. As a result, we conclude that laser with shorter wavelength e.g. Blue is more effective than longer wavelengths e.g. IR or Red, in reducing the oxidant parameters (AGE, AOPP, and ox-LDL) levels in Intravenous LLLT.
    VL  - 6
    IS  - 2
    ER  - 

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Author Information
  • Endocrinology and Metabolism Research Center (EMRC), Valiasr Hospital, School of Medicine, Tehran University of Medical Science, Tehran, Iran

  • Laser and Medical Physics Lab, Department of Physics, Sharif University of Technology, Tehran, Iran

  • Laser and Medical Physics Lab, Department of Physics, Sharif University of Technology, Tehran, Iran

  • Laser and Medical Physics Lab, Department of Physics, Sharif University of Technology, Tehran, Iran

  • Laser and Medical Physics Lab, Department of Physics, Sharif University of Technology, Tehran, Iran

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