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Evaluation of Quality of Life Indicators of Patients with Arterial Hypertension and Comorbid Chronic Obstructive Pulmonary Disease

Received: 2 March 2022     Accepted: 21 March 2022     Published: 20 April 2022
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Abstract

The purpose of this study to analyze the quality of life (QoL) of patients in accordance with a personalized approach in the complex drug treatment of patients with hypertension and comorbid chronic obstructive pulmonary disease (COPD). Materials and methods: the analysis of two groups of male patients. The presence of left ventricular remodeling with preserved ejection fraction (≥ 50%) – Group 1 with antihypertensive therapy of valsartan with amlodipine, or mid-range (45-49%) – Group 2 with combination of candesartan and nebivolol. The general clinical examination was performed using international clinical scales and validated SF-36 and SGRQ questionnaires. Comparison of QoL parameters according to the SF-36 questionnaire revealed a significant difference between pre- and post-treatment parameters in Groups 1 and 2 (p <0.05). In conclusion, a comprehensive approach is recommended in patients with hypertension and comorbid COPD, which provide long-term antihypertensive and bronchodilator effects and are recommended for use in patients. After 6 months of comprehensive combination therapy, the condition of patients has significantly improved, as evidenced by changes in QoL according to the SF-36 and SGRQ questionnaires. All indicators of mental and physical components of the SF-36 questionnaire significantly increased and the values of the categories of the specific respiratory questionnaire SGRQ decreased.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 8, Issue 2)
DOI 10.11648/j.ijcems.20220802.11
Page(s) 20-23
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Quality of Life, Arterial Hypertension, Chronic Obstructive Pulmonary Disease, Antihypertensive Therapy

References
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[2] Borghi C, Tubach F, De Backer G, Dallongeville J, Guallar E, Medina J, et al. (2016). Lack of control of hypertension in primary cardiovascular disease prevention in Europe: Results from the EURIKA study. Int J Cardiol. Sep 1; 218: 83–8.
[3] Бондарчук СА. (2018). Вибір між фіксованими комбінаціями блокаторів ренін-ангіотензин-альдостеронової системи з антагоністом кальцію: що обрати? [Choosing between fixed combinations of renin-angiotensin-aldosterone system blockers with a calcium antagonist: what to choose?] Ліки України; 3 (36): 4–10.
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[5] Адашева ТВ, Бабак СЛ, Горбунова МВ, Задионченко ВС, Зыков КА, Кароли НА, Ли ВВ, Ребров АП. (2017). Национальные клинические рекомендации: диагностика и лечение пациентов с хронической обструктивной болезнью легких и артериальной гипертензией. [Інтернет] [National clinical guidelines: diagnosis and treatment of patients with chronic obstructive pulmonary disease and hypertension] https://www.rnmot.ru/public/uploads/RNMOT/clinical/2017/ХОБЛ_и_АГ_Малявин_250618.pdf
[6] Артериальная гипертензия у взрослых. Профессиональные ассоциации. (2020). Клин. рек. Москва: Российское кардиологическое общество; [Hypertension in adults. Professional associations] Доступно: http://webmed.irkutsk.ru/doc/pdf/fedhypert.pdf
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    Iryna Vysochyna, Tetiana Burtniak. (2022). Evaluation of Quality of Life Indicators of Patients with Arterial Hypertension and Comorbid Chronic Obstructive Pulmonary Disease. International Journal of Clinical and Experimental Medical Sciences, 8(2), 20-23. https://doi.org/10.11648/j.ijcems.20220802.11

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    ACS Style

    Iryna Vysochyna; Tetiana Burtniak. Evaluation of Quality of Life Indicators of Patients with Arterial Hypertension and Comorbid Chronic Obstructive Pulmonary Disease. Int. J. Clin. Exp. Med. Sci. 2022, 8(2), 20-23. doi: 10.11648/j.ijcems.20220802.11

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    AMA Style

    Iryna Vysochyna, Tetiana Burtniak. Evaluation of Quality of Life Indicators of Patients with Arterial Hypertension and Comorbid Chronic Obstructive Pulmonary Disease. Int J Clin Exp Med Sci. 2022;8(2):20-23. doi: 10.11648/j.ijcems.20220802.11

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  • @article{10.11648/j.ijcems.20220802.11,
      author = {Iryna Vysochyna and Tetiana Burtniak},
      title = {Evaluation of Quality of Life Indicators of Patients with Arterial Hypertension and Comorbid Chronic Obstructive Pulmonary Disease},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {8},
      number = {2},
      pages = {20-23},
      doi = {10.11648/j.ijcems.20220802.11},
      url = {https://doi.org/10.11648/j.ijcems.20220802.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20220802.11},
      abstract = {The purpose of this study to analyze the quality of life (QoL) of patients in accordance with a personalized approach in the complex drug treatment of patients with hypertension and comorbid chronic obstructive pulmonary disease (COPD). Materials and methods: the analysis of two groups of male patients. The presence of left ventricular remodeling with preserved ejection fraction (≥ 50%) – Group 1 with antihypertensive therapy of valsartan with amlodipine, or mid-range (45-49%) – Group 2 with combination of candesartan and nebivolol. The general clinical examination was performed using international clinical scales and validated SF-36 and SGRQ questionnaires. Comparison of QoL parameters according to the SF-36 questionnaire revealed a significant difference between pre- and post-treatment parameters in Groups 1 and 2 (p <0.05). In conclusion, a comprehensive approach is recommended in patients with hypertension and comorbid COPD, which provide long-term antihypertensive and bronchodilator effects and are recommended for use in patients. After 6 months of comprehensive combination therapy, the condition of patients has significantly improved, as evidenced by changes in QoL according to the SF-36 and SGRQ questionnaires. All indicators of mental and physical components of the SF-36 questionnaire significantly increased and the values of the categories of the specific respiratory questionnaire SGRQ decreased.},
     year = {2022}
    }
    

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    AU  - Iryna Vysochyna
    AU  - Tetiana Burtniak
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    AB  - The purpose of this study to analyze the quality of life (QoL) of patients in accordance with a personalized approach in the complex drug treatment of patients with hypertension and comorbid chronic obstructive pulmonary disease (COPD). Materials and methods: the analysis of two groups of male patients. The presence of left ventricular remodeling with preserved ejection fraction (≥ 50%) – Group 1 with antihypertensive therapy of valsartan with amlodipine, or mid-range (45-49%) – Group 2 with combination of candesartan and nebivolol. The general clinical examination was performed using international clinical scales and validated SF-36 and SGRQ questionnaires. Comparison of QoL parameters according to the SF-36 questionnaire revealed a significant difference between pre- and post-treatment parameters in Groups 1 and 2 (p <0.05). In conclusion, a comprehensive approach is recommended in patients with hypertension and comorbid COPD, which provide long-term antihypertensive and bronchodilator effects and are recommended for use in patients. After 6 months of comprehensive combination therapy, the condition of patients has significantly improved, as evidenced by changes in QoL according to the SF-36 and SGRQ questionnaires. All indicators of mental and physical components of the SF-36 questionnaire significantly increased and the values of the categories of the specific respiratory questionnaire SGRQ decreased.
    VL  - 8
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Author Information
  • Department of Family Medicine FPE, Dnipro State Medical University, Dnipro, Ukraine

  • Department of Family Medicine FPE, Dnipro State Medical University, Dnipro, Ukraine

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