@article{10.11648/j.ijcems.20220803.11,
  author = {Fadhillah Ardiana Azmi and Yeniar Fitrianingrum and Ahmad Fiqri and Siti Ma’rufah and Moerbono Mochtar and Suci Widhiati},
  title = {Oral Albendazole Is Superior to Permethrin 5% for Scabies Treatment in Boarding School Indonesia},
  journal = {International Journal of Clinical and Experimental Medical Sciences},
  volume = {8},
  number = {3},
  pages = {38-43},
  doi = {10.11648/j.ijcems.20220803.11},
  url = {https://doi.org/10.11648/j.ijcems.20220803.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20220803.11},
  abstract = {Scabies is a skin disease caused by Sarcoptes scabiei infestation and is classified as a neglected tropical disease (NTD). Permethrin 5% is the first-line treatment for scabies. However, adherence and accuracy in topical creams are common problems. Thus, it is necessary to think of alternative medication that is more accessible, more straightforward, and lower the risk of resistance. Albendazole appears to be an alternative therapy for eradicating scabies in the community base. Sixty subjects diagnosed with scabies were recruited and divided into two groups with randomization. The first group was given 400 mg oral albendazole for three consecutive days on the first and second week. The second group was applied permethrin 5% to the whole body once on the first night of the first and second week. The evaluation was carried out for four weeks, and improvement was stated absence of new lesions and healing of old lesions and pruritus. Data were analyzed using SPSS software (version 25, SPSS Inc., Chicago., IL). The X2 test was used to examine the difference between groups, and p < 0.05 was considered significant. The cure rate of albendazole was significantly superior to permethrin topical (90.0% vs. 63.3%) with a p-value of 0.015. This study revealed the effectiveness of oral albendazole 400 mg/day for three consecutive days in the first and second weeks for treating scabies to topical permethrin 5%. No side effect seen in the use of albendazole and topical permethrin during the study. Albendazole could be an alternative drug option to eradicate scabies in low-middle-income countries.},
 year = {2022}
}

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TY  - JOUR
T1  - Oral Albendazole Is Superior to Permethrin 5% for Scabies Treatment in Boarding School Indonesia
AU  - Fadhillah Ardiana Azmi
AU  - Yeniar Fitrianingrum
AU  - Ahmad Fiqri
AU  - Siti Ma’rufah
AU  - Moerbono Mochtar
AU  - Suci Widhiati
Y1  - 2022/05/12
PY  - 2022
N1  - https://doi.org/10.11648/j.ijcems.20220803.11
DO  - 10.11648/j.ijcems.20220803.11
T2  - International Journal of Clinical and Experimental Medical Sciences
JF  - International Journal of Clinical and Experimental Medical Sciences
JO  - International Journal of Clinical and Experimental Medical Sciences
SP  - 38
EP  - 43
PB  - Science Publishing Group
SN  - 2469-8032
UR  - https://doi.org/10.11648/j.ijcems.20220803.11
AB  - Scabies is a skin disease caused by Sarcoptes scabiei infestation and is classified as a neglected tropical disease (NTD). Permethrin 5% is the first-line treatment for scabies. However, adherence and accuracy in topical creams are common problems. Thus, it is necessary to think of alternative medication that is more accessible, more straightforward, and lower the risk of resistance. Albendazole appears to be an alternative therapy for eradicating scabies in the community base. Sixty subjects diagnosed with scabies were recruited and divided into two groups with randomization. The first group was given 400 mg oral albendazole for three consecutive days on the first and second week. The second group was applied permethrin 5% to the whole body once on the first night of the first and second week. The evaluation was carried out for four weeks, and improvement was stated absence of new lesions and healing of old lesions and pruritus. Data were analyzed using SPSS software (version 25, SPSS Inc., Chicago., IL). The X2 test was used to examine the difference between groups, and p < 0.05 was considered significant. The cure rate of albendazole was significantly superior to permethrin topical (90.0% vs. 63.3%) with a p-value of 0.015. This study revealed the effectiveness of oral albendazole 400 mg/day for three consecutive days in the first and second weeks for treating scabies to topical permethrin 5%. No side effect seen in the use of albendazole and topical permethrin during the study. Albendazole could be an alternative drug option to eradicate scabies in low-middle-income countries.
VL  - 8
IS  - 3
ER  - 

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