Endocrine Disruptor Compounds (EDC) Effects on Reproduction

Thi Mong Diep Nguyen

doi:doi:10.11648/j.ijde.20180301.14

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Endocrine Disruptor Compounds (EDC) Effects on Reproduction

Thi Mong Diep Nguyen

Published in International Journal of Diabetes and Endocrinology (Volume 3, Issue 1)

Received: 25 March 2018 Accepted: 12 April 2018 Published: 14 May 2018

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Abstract

A large number of industrial chemical products (paints, flame retardants, pharmaceuticals, pesticides) are suspected or proved to act as endocrine disruptor compounds (EDCs). In the present survey of the literature, the main issue is to consider how to classify individual products as EDC or not. In this perspective, the different mechanisms leading to endocrine disruption are described: either by direct interaction with hormone receptors leading to its stimulation or inhibition, or by effect on endogenous hormone concentration through stimulation or inhibition of its synthesis or its degradation, or its binding to transport binding proteins. The present review takes particularly in consideration the effects of EDCs on the endocrine control of Reproduction in human and animals. Indeed, a number of EDCs can act as anti-androgens, anti-estrogens, and steroidogenic enzyme inhibitors that interfere with steroid action or production and thus can alter reproductive health.

Published in	International Journal of Diabetes and Endocrinology (Volume 3, Issue 1)
DOI	10.11648/j.ijde.20180301.14
Page(s)	18-22
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Endocrine Disruption, Endogenous Hormone, Reproduction, Reproductive Health

References

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[8]	Yin P, Li YW, Chen QL, Liu ZH (2017) Diethylstilbestrol, flutamide and their combination impaired the spermatogenesis of male adult zebrafish through disrupting HPG axis, meiosis and apoptosis. Aquat Toxicol 185: 129-137.
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APA Style

Thi Mong Diep Nguyen. (2018). Endocrine Disruptor Compounds (EDC) Effects on Reproduction. International Journal of Diabetes and Endocrinology, 3(1), 18-22. https://doi.org/10.11648/j.ijde.20180301.14

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ACS Style

Thi Mong Diep Nguyen. Endocrine Disruptor Compounds (EDC) Effects on Reproduction. Int. J. Diabetes Endocrinol. 2018, 3(1), 18-22. doi: 10.11648/j.ijde.20180301.14

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AMA Style

Thi Mong Diep Nguyen. Endocrine Disruptor Compounds (EDC) Effects on Reproduction. Int J Diabetes Endocrinol. 2018;3(1):18-22. doi: 10.11648/j.ijde.20180301.14

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@article{10.11648/j.ijde.20180301.14,
  author = {Thi Mong Diep Nguyen},
  title = {Endocrine Disruptor Compounds (EDC) Effects on Reproduction},
  journal = {International Journal of Diabetes and Endocrinology},
  volume = {3},
  number = {1},
  pages = {18-22},
  doi = {10.11648/j.ijde.20180301.14},
  url = {https://doi.org/10.11648/j.ijde.20180301.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20180301.14},
  abstract = {A large number of industrial chemical products (paints, flame retardants, pharmaceuticals, pesticides) are suspected or proved to act as endocrine disruptor compounds (EDCs). In the present survey of the literature, the main issue is to consider how to classify individual products as EDC or not. In this perspective, the different mechanisms leading to endocrine disruption are described: either by direct interaction with hormone receptors leading to its stimulation or inhibition, or by effect on endogenous hormone concentration through stimulation or inhibition of its synthesis or its degradation, or its binding to transport binding proteins. The present review takes particularly in consideration the effects of EDCs on the endocrine control of Reproduction in human and animals. Indeed, a number of EDCs can act as anti-androgens, anti-estrogens, and steroidogenic enzyme inhibitors that interfere with steroid action or production and thus can alter reproductive health.},
 year = {2018}
}

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TY  - JOUR
T1  - Endocrine Disruptor Compounds (EDC) Effects on Reproduction
AU  - Thi Mong Diep Nguyen
Y1  - 2018/05/14
PY  - 2018
N1  - https://doi.org/10.11648/j.ijde.20180301.14
DO  - 10.11648/j.ijde.20180301.14
T2  - International Journal of Diabetes and Endocrinology
JF  - International Journal of Diabetes and Endocrinology
JO  - International Journal of Diabetes and Endocrinology
SP  - 18
EP  - 22
PB  - Science Publishing Group
SN  - 2640-1371
UR  - https://doi.org/10.11648/j.ijde.20180301.14
AB  - A large number of industrial chemical products (paints, flame retardants, pharmaceuticals, pesticides) are suspected or proved to act as endocrine disruptor compounds (EDCs). In the present survey of the literature, the main issue is to consider how to classify individual products as EDC or not. In this perspective, the different mechanisms leading to endocrine disruption are described: either by direct interaction with hormone receptors leading to its stimulation or inhibition, or by effect on endogenous hormone concentration through stimulation or inhibition of its synthesis or its degradation, or its binding to transport binding proteins. The present review takes particularly in consideration the effects of EDCs on the endocrine control of Reproduction in human and animals. Indeed, a number of EDCs can act as anti-androgens, anti-estrogens, and steroidogenic enzyme inhibitors that interfere with steroid action or production and thus can alter reproductive health.
VL  - 3
IS  - 1
ER  -

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Author Information

Thi Mong Diep Nguyen

Faculty of Biology-Agricultural Engineering, Quy Nhon University, Quy Nhon, Viet Nam

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APA Style

Thi Mong Diep Nguyen. (2018). Endocrine Disruptor Compounds (EDC) Effects on Reproduction. International Journal of Diabetes and Endocrinology, 3(1), 18-22. https://doi.org/10.11648/j.ijde.20180301.14

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ACS Style

Thi Mong Diep Nguyen. Endocrine Disruptor Compounds (EDC) Effects on Reproduction. Int. J. Diabetes Endocrinol. 2018, 3(1), 18-22. doi: 10.11648/j.ijde.20180301.14

Copy | Download

AMA Style

Thi Mong Diep Nguyen. Endocrine Disruptor Compounds (EDC) Effects on Reproduction. Int J Diabetes Endocrinol. 2018;3(1):18-22. doi: 10.11648/j.ijde.20180301.14

Copy | Download

@article{10.11648/j.ijde.20180301.14,
  author = {Thi Mong Diep Nguyen},
  title = {Endocrine Disruptor Compounds (EDC) Effects on Reproduction},
  journal = {International Journal of Diabetes and Endocrinology},
  volume = {3},
  number = {1},
  pages = {18-22},
  doi = {10.11648/j.ijde.20180301.14},
  url = {https://doi.org/10.11648/j.ijde.20180301.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20180301.14},
  abstract = {A large number of industrial chemical products (paints, flame retardants, pharmaceuticals, pesticides) are suspected or proved to act as endocrine disruptor compounds (EDCs). In the present survey of the literature, the main issue is to consider how to classify individual products as EDC or not. In this perspective, the different mechanisms leading to endocrine disruption are described: either by direct interaction with hormone receptors leading to its stimulation or inhibition, or by effect on endogenous hormone concentration through stimulation or inhibition of its synthesis or its degradation, or its binding to transport binding proteins. The present review takes particularly in consideration the effects of EDCs on the endocrine control of Reproduction in human and animals. Indeed, a number of EDCs can act as anti-androgens, anti-estrogens, and steroidogenic enzyme inhibitors that interfere with steroid action or production and thus can alter reproductive health.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Endocrine Disruptor Compounds (EDC) Effects on Reproduction
AU  - Thi Mong Diep Nguyen
Y1  - 2018/05/14
PY  - 2018
N1  - https://doi.org/10.11648/j.ijde.20180301.14
DO  - 10.11648/j.ijde.20180301.14
T2  - International Journal of Diabetes and Endocrinology
JF  - International Journal of Diabetes and Endocrinology
JO  - International Journal of Diabetes and Endocrinology
SP  - 18
EP  - 22
PB  - Science Publishing Group
SN  - 2640-1371
UR  - https://doi.org/10.11648/j.ijde.20180301.14
AB  - A large number of industrial chemical products (paints, flame retardants, pharmaceuticals, pesticides) are suspected or proved to act as endocrine disruptor compounds (EDCs). In the present survey of the literature, the main issue is to consider how to classify individual products as EDC or not. In this perspective, the different mechanisms leading to endocrine disruption are described: either by direct interaction with hormone receptors leading to its stimulation or inhibition, or by effect on endogenous hormone concentration through stimulation or inhibition of its synthesis or its degradation, or its binding to transport binding proteins. The present review takes particularly in consideration the effects of EDCs on the endocrine control of Reproduction in human and animals. Indeed, a number of EDCs can act as anti-androgens, anti-estrogens, and steroidogenic enzyme inhibitors that interfere with steroid action or production and thus can alter reproductive health.
VL  - 3
IS  - 1
ER  -

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