Objective: to assess the impact of initial hyperglycaemia on the mortality of intensive care patients. Methods: This is a cross-sectional study involving 217 patients. The data was collected from patient files, then collected and stored on pre-established survey sheets. Data were entered into the computer using Epi Info software and analyzed using the Statistical Package for Social Science (SPSS) version 21.0 program. The chi-square test (Fisher exact) associated with the risk calculation allowed us to compare the groups of hyperglycemic (HG) and normo-glycemic (NG) patients and also the previously known diabetic hyperglycemics and the non-diabetics. The value of p < 0.05 was considered as the threshold of statistical significance. Results: initial hyperglycaemia is common in intensive care regardless of diabetic status. The mean age of the patients was 44.4 years; the male sex was predominant with a sex ratio of 1.2 (M/F). Diabetics accounted for 14.7%. Polytrauma was the most encountered pathology, followed by surgical pathologies, cerebrovascular accidents (CVA), sepsis and others. The hyperglycemics had presented more deaths than the normo-glycemics, with a significant difference. The long stay was observed more in normoglycemics than in hyperglycemics, with a significant difference. Hyperglycemia in the group of non-diabetic patients was accompanied by higher mortality than that in the group of diabetic patients. Conclusion: Mortality was high in the group of non-diabetic hyperglycemic patients, 88.9% vs 11.1% of hyperglycemic diabetic patients.
| Published in | International Journal of Diabetes and Endocrinology (Volume 8, Issue 2) |
| DOI | 10.11648/j.ijde.20230802.12 |
| Page(s) | 31-36 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Initial Hyperglycemia, Mortality, Resuscitation
| [1] | Martin Buysschaert, Clinical Diabetology. De Boeck university, P. 10. |
| [2] | Devos P, Preiser JC – Current practice of glycaemia control in European intensive care units – Acta Gastroenterologica Belgica – 2005– Belgian week - Oral session Abstract X03. |
| [3] | Mc Cowen KC, Malhotra A, Bistrian BR. Stress-induced hyperglycemia. Crit Care Clin 2001; 17: 107–24. |
| [4] | Thorell A, Nygren J, Ljungqvist O. Insulin resistance: a marker of surgical stress. curr Opinion Wink Nutr Metab Care 1999; 2: 69–78. |
| [5] | Van den Berghe G. How does blood glucose control with insulin save lives in intensive care? J Clin Invest 2004; 114: 1887-95. |
| [6] | Andreelli F, Jacquier D, Keufer F. Anti-inflammatory properties of insulin in intensive care patients. Resuscitation 2006; 15: 467-73. |
| [7] | Umpierrez G, Isaacs S, Bazargan N, You X, Thaler L, Kitbachi A. Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. J Clin Endocrinol Metab 2002; 87; 978-82. |
| [8] | Cely CM; Arora P.; Quartin AA, Kett DH, Schein RM. Relationship of baseline glycosis homeostasis to hyperglycemia during medical critical illness. Chest, 2004, 126: 879-87. |
| [9] | KrinsleyJS. Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients. Mayo Clin Proc 2003; 78: 1471–8. |
| [10] | Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, et al. Intensive insulin therapy in critically ill patients. N English J Med 2001; 345: 1359–67. |
| [11] | Van den Berghe G, Wilmer A, Hermans G, Meersseman W, Wouters PJ, Milants I, et al. Intensive Insulin Therapy in the Medical ICU. N English J Med 2006; 354: 449–61. |
| [12] | KrinsleyJS. Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clin Proc 2004; 79: 992-1000. |
| [13] | Lepira et al. Hyperglycemia and in-hospital mortality in patients with acute stroke in Mbuji- mayi, the Democratic Republic of the Congo. Amn. Afr. Med., vol. 3, N°3, June 2010: 469-77. |
| [14] | Mbala R. Prognostic value of undernutrition and severe sepsis in the morbidity and mortality of peritonitis. Specialization dissertation. _ September 2008. |
| [15] | Mwembia A. Morbimortality of postoperative peritonitis. December 2012. |
| [16] | Wahab NN, Cowden EA, Pearce NJ, et al. Is blood glucose and independent predictor of mortality in acute myocardial infarction in the thrombolytic era? J Am Coll Cardiol 2002; 40: 1748-54. |
| [17] | Goldberg RJ, Kramer DG, Lessard D, Yarzebski J, Gore JM. Serum glucose levels and hospital outcomes in patients with acute myocardial infarction without prior diabetes: a community-wide perspective. Coron Artery Dis 2007; 18: 125-31. |
| [18] | Leonidou L, Mouzaki A, Michalaki M, et al. Cytokine production and hospital mortality in patients with sepsis-induced stress hyperglycemia. J Infection 2007; 55: 340-6. |
| [19] | Wang Y, Lim LLY, Levi C, Heller R, Fisher J. Influence of hyperglycemia on stroke mortality. J Stroke Cerebrovascular Dis 2001; 10: 11-8. |
APA Style
Philomene Diyoyo, Gibency Mfulani, Christian Nantulu, Jean-Claude Mubenga, Didier Kandongo, et al. (2023). Impact of Initial Hyperglycaemia on Mortality in Reanimation. International Journal of Diabetes and Endocrinology, 8(2), 31-36. https://doi.org/10.11648/j.ijde.20230802.12
ACS Style
Philomene Diyoyo; Gibency Mfulani; Christian Nantulu; Jean-Claude Mubenga; Didier Kandongo, et al. Impact of Initial Hyperglycaemia on Mortality in Reanimation. Int. J. Diabetes Endocrinol. 2023, 8(2), 31-36. doi: 10.11648/j.ijde.20230802.12
AMA Style
Philomene Diyoyo, Gibency Mfulani, Christian Nantulu, Jean-Claude Mubenga, Didier Kandongo, et al. Impact of Initial Hyperglycaemia on Mortality in Reanimation. Int J Diabetes Endocrinol. 2023;8(2):31-36. doi: 10.11648/j.ijde.20230802.12
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author = {Philomene Diyoyo and Gibency Mfulani and Christian Nantulu and Jean-Claude Mubenga and Didier Kandongo and Raissa Assani and Fiston Nganga and Didier Mayemba and Hervé Mole and Marcel Kamwanga and Denis Mutombo and Adolphe Mutombo and Joel Cimbila and Laurence Bamporiki and Rodrigue Ngwizani and Hugues Kwama and Berthe Barhayiga},
title = {Impact of Initial Hyperglycaemia on Mortality in Reanimation},
journal = {International Journal of Diabetes and Endocrinology},
volume = {8},
number = {2},
pages = {31-36},
doi = {10.11648/j.ijde.20230802.12},
url = {https://doi.org/10.11648/j.ijde.20230802.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20230802.12},
abstract = {Objective: to assess the impact of initial hyperglycaemia on the mortality of intensive care patients. Methods: This is a cross-sectional study involving 217 patients. The data was collected from patient files, then collected and stored on pre-established survey sheets. Data were entered into the computer using Epi Info software and analyzed using the Statistical Package for Social Science (SPSS) version 21.0 program. The chi-square test (Fisher exact) associated with the risk calculation allowed us to compare the groups of hyperglycemic (HG) and normo-glycemic (NG) patients and also the previously known diabetic hyperglycemics and the non-diabetics. The value of p Results: initial hyperglycaemia is common in intensive care regardless of diabetic status. The mean age of the patients was 44.4 years; the male sex was predominant with a sex ratio of 1.2 (M/F). Diabetics accounted for 14.7%. Polytrauma was the most encountered pathology, followed by surgical pathologies, cerebrovascular accidents (CVA), sepsis and others. The hyperglycemics had presented more deaths than the normo-glycemics, with a significant difference. The long stay was observed more in normoglycemics than in hyperglycemics, with a significant difference. Hyperglycemia in the group of non-diabetic patients was accompanied by higher mortality than that in the group of diabetic patients. Conclusion: Mortality was high in the group of non-diabetic hyperglycemic patients, 88.9% vs 11.1% of hyperglycemic diabetic patients.},
year = {2023}
}
TY - JOUR T1 - Impact of Initial Hyperglycaemia on Mortality in Reanimation AU - Philomene Diyoyo AU - Gibency Mfulani AU - Christian Nantulu AU - Jean-Claude Mubenga AU - Didier Kandongo AU - Raissa Assani AU - Fiston Nganga AU - Didier Mayemba AU - Hervé Mole AU - Marcel Kamwanga AU - Denis Mutombo AU - Adolphe Mutombo AU - Joel Cimbila AU - Laurence Bamporiki AU - Rodrigue Ngwizani AU - Hugues Kwama AU - Berthe Barhayiga Y1 - 2023/08/31 PY - 2023 N1 - https://doi.org/10.11648/j.ijde.20230802.12 DO - 10.11648/j.ijde.20230802.12 T2 - International Journal of Diabetes and Endocrinology JF - International Journal of Diabetes and Endocrinology JO - International Journal of Diabetes and Endocrinology SP - 31 EP - 36 PB - Science Publishing Group SN - 2640-1371 UR - https://doi.org/10.11648/j.ijde.20230802.12 AB - Objective: to assess the impact of initial hyperglycaemia on the mortality of intensive care patients. Methods: This is a cross-sectional study involving 217 patients. The data was collected from patient files, then collected and stored on pre-established survey sheets. Data were entered into the computer using Epi Info software and analyzed using the Statistical Package for Social Science (SPSS) version 21.0 program. The chi-square test (Fisher exact) associated with the risk calculation allowed us to compare the groups of hyperglycemic (HG) and normo-glycemic (NG) patients and also the previously known diabetic hyperglycemics and the non-diabetics. The value of p Results: initial hyperglycaemia is common in intensive care regardless of diabetic status. The mean age of the patients was 44.4 years; the male sex was predominant with a sex ratio of 1.2 (M/F). Diabetics accounted for 14.7%. Polytrauma was the most encountered pathology, followed by surgical pathologies, cerebrovascular accidents (CVA), sepsis and others. The hyperglycemics had presented more deaths than the normo-glycemics, with a significant difference. The long stay was observed more in normoglycemics than in hyperglycemics, with a significant difference. Hyperglycemia in the group of non-diabetic patients was accompanied by higher mortality than that in the group of diabetic patients. Conclusion: Mortality was high in the group of non-diabetic hyperglycemic patients, 88.9% vs 11.1% of hyperglycemic diabetic patients. VL - 8 IS - 2 ER -
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