Background: Evidence about COVID-19 on cardiac injury was insufficient. Objectives: To summarize available data on clinical manifestations of acute cardiac injury during the COVID-19 outbreak. Methods: A systematic literature search from December 1, 2019 to April, 12, 2020 was made of those databases: Pubmed, Embase, wanfang, CKNI, to identify all observational studies that reported presentation of cardiac injury, including acute cardiac injury, cardiac symptoms, cardiac failure, shock, arrhythmia. A random-effects model was used to pool results. Heterogeneity was assessed using I2. Publication bias was assessed using Egger's test. Results: 3863 confirmed COVID-19 infected patients from 22 studies were included in the meta-analysis. Among the patients, the incidence rate of acute cardiac injury was 18% [95%CI 12–23], chest pain (4% [95%CI 2–5]), chest distress (31% [95%CI 16–47]), and palpitations (4% [95%CI 0–7]) were the most common clinical symptoms related to acute cardiac injury. The incidence with heart failure was 22% [95%CI 17–28], the incidence with shock was 9% [95%CI 3–14], and the incidence with arrhythmia was 13% [95%CI 8–19]. Conclusions: Acute cardiac injury without clinical symptoms should be paid more attention among the confirmed COVID-19 infected patients. In addition, this highlights the need to effectively monitor heart health to prevent the cardiac complications (cardiac failure, shock, arrhythmia) in patients infected with COVID-19.
| Published in | International Journal of Infectious Diseases and Therapy (Volume 5, Issue 4) |
| DOI | 10.11648/j.ijidt.20200504.16 |
| Page(s) | 136-144 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
COVID-19, Cardiac Injury, Coronavirus, Chest Pain, Acute Cardiac Injury, Cardiac Failure, Shock, Arrhythmia
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APA Style
Mingyan Gong, Jun Guo. (2020). Clinical Manifestations of Myocardial Injury Associated with the 2019 Novel Coronavirus Disease in Chinese Population: A Meta-analysis. International Journal of Infectious Diseases and Therapy, 5(4), 136-144. https://doi.org/10.11648/j.ijidt.20200504.16
ACS Style
Mingyan Gong; Jun Guo. Clinical Manifestations of Myocardial Injury Associated with the 2019 Novel Coronavirus Disease in Chinese Population: A Meta-analysis. Int. J. Infect. Dis. Ther. 2020, 5(4), 136-144. doi: 10.11648/j.ijidt.20200504.16
AMA Style
Mingyan Gong, Jun Guo. Clinical Manifestations of Myocardial Injury Associated with the 2019 Novel Coronavirus Disease in Chinese Population: A Meta-analysis. Int J Infect Dis Ther. 2020;5(4):136-144. doi: 10.11648/j.ijidt.20200504.16
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Download@article{10.11648/j.ijidt.20200504.16,
author = {Mingyan Gong and Jun Guo},
title = {Clinical Manifestations of Myocardial Injury Associated with the 2019 Novel Coronavirus Disease in Chinese Population: A Meta-analysis},
journal = {International Journal of Infectious Diseases and Therapy},
volume = {5},
number = {4},
pages = {136-144},
doi = {10.11648/j.ijidt.20200504.16},
url = {https://doi.org/10.11648/j.ijidt.20200504.16},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20200504.16},
abstract = {Background: Evidence about COVID-19 on cardiac injury was insufficient. Objectives: To summarize available data on clinical manifestations of acute cardiac injury during the COVID-19 outbreak. Methods: A systematic literature search from December 1, 2019 to April, 12, 2020 was made of those databases: Pubmed, Embase, wanfang, CKNI, to identify all observational studies that reported presentation of cardiac injury, including acute cardiac injury, cardiac symptoms, cardiac failure, shock, arrhythmia. A random-effects model was used to pool results. Heterogeneity was assessed using I2. Publication bias was assessed using Egger's test. Results: 3863 confirmed COVID-19 infected patients from 22 studies were included in the meta-analysis. Among the patients, the incidence rate of acute cardiac injury was 18% [95%CI 12–23], chest pain (4% [95%CI 2–5]), chest distress (31% [95%CI 16–47]), and palpitations (4% [95%CI 0–7]) were the most common clinical symptoms related to acute cardiac injury. The incidence with heart failure was 22% [95%CI 17–28], the incidence with shock was 9% [95%CI 3–14], and the incidence with arrhythmia was 13% [95%CI 8–19]. Conclusions: Acute cardiac injury without clinical symptoms should be paid more attention among the confirmed COVID-19 infected patients. In addition, this highlights the need to effectively monitor heart health to prevent the cardiac complications (cardiac failure, shock, arrhythmia) in patients infected with COVID-19.},
year = {2020}
}
TY - JOUR T1 - Clinical Manifestations of Myocardial Injury Associated with the 2019 Novel Coronavirus Disease in Chinese Population: A Meta-analysis AU - Mingyan Gong AU - Jun Guo Y1 - 2020/12/11 PY - 2020 N1 - https://doi.org/10.11648/j.ijidt.20200504.16 DO - 10.11648/j.ijidt.20200504.16 T2 - International Journal of Infectious Diseases and Therapy JF - International Journal of Infectious Diseases and Therapy JO - International Journal of Infectious Diseases and Therapy SP - 136 EP - 144 PB - Science Publishing Group SN - 2578-966X UR - https://doi.org/10.11648/j.ijidt.20200504.16 AB - Background: Evidence about COVID-19 on cardiac injury was insufficient. Objectives: To summarize available data on clinical manifestations of acute cardiac injury during the COVID-19 outbreak. Methods: A systematic literature search from December 1, 2019 to April, 12, 2020 was made of those databases: Pubmed, Embase, wanfang, CKNI, to identify all observational studies that reported presentation of cardiac injury, including acute cardiac injury, cardiac symptoms, cardiac failure, shock, arrhythmia. A random-effects model was used to pool results. Heterogeneity was assessed using I2. Publication bias was assessed using Egger's test. Results: 3863 confirmed COVID-19 infected patients from 22 studies were included in the meta-analysis. Among the patients, the incidence rate of acute cardiac injury was 18% [95%CI 12–23], chest pain (4% [95%CI 2–5]), chest distress (31% [95%CI 16–47]), and palpitations (4% [95%CI 0–7]) were the most common clinical symptoms related to acute cardiac injury. The incidence with heart failure was 22% [95%CI 17–28], the incidence with shock was 9% [95%CI 3–14], and the incidence with arrhythmia was 13% [95%CI 8–19]. Conclusions: Acute cardiac injury without clinical symptoms should be paid more attention among the confirmed COVID-19 infected patients. In addition, this highlights the need to effectively monitor heart health to prevent the cardiac complications (cardiac failure, shock, arrhythmia) in patients infected with COVID-19. VL - 5 IS - 4 ER -
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