PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer

Samina Qamar; Uzair Bashir Chaudhary

doi:doi:10.11648/j.jctr.20170505.11

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PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer

Samina Qamar, Uzair Bashir Chaudhary

Published in Journal of Cancer Treatment and Research (Volume 5, Issue 5)

Received: 18 July 2017 Accepted: 11 August 2017 Published: 4 September 2017

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Abstract

Advanced bladder cancer (BC) has a poor prognosis with historically limited therapeutic options. Immunotherapy has emerged as a viable option for patients with advanced bladder cancer in the second line setting. Immune check point inhibitors have shown promising results in management of this disease. In this review we will discuss the recently evolving role of anti PD-1/PD-L1 inhibitors (programmed cell death protein-1 and programmed death ligand-1) for managing this disease.

Published in	Journal of Cancer Treatment and Research (Volume 5, Issue 5)
DOI	10.11648/j.jctr.20170505.11
Page(s)	71-80
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Cancer, Bladder, Immunotherapy, PD-L1, PD-1

References

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Samina Qamar, Uzair Bashir Chaudhary. (2017). PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer. Journal of Cancer Treatment and Research, 5(5), 71-80. https://doi.org/10.11648/j.jctr.20170505.11

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Samina Qamar; Uzair Bashir Chaudhary. PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer. J. Cancer Treat. Res. 2017, 5(5), 71-80. doi: 10.11648/j.jctr.20170505.11

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AMA Style

Samina Qamar, Uzair Bashir Chaudhary. PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer. J Cancer Treat Res. 2017;5(5):71-80. doi: 10.11648/j.jctr.20170505.11

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@article{10.11648/j.jctr.20170505.11,
  author = {Samina Qamar and Uzair Bashir Chaudhary},
  title = {PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer},
  journal = {Journal of Cancer Treatment and Research},
  volume = {5},
  number = {5},
  pages = {71-80},
  doi = {10.11648/j.jctr.20170505.11},
  url = {https://doi.org/10.11648/j.jctr.20170505.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20170505.11},
  abstract = {Advanced bladder cancer (BC) has a poor prognosis with historically limited therapeutic options. Immunotherapy has emerged as a viable option for patients with advanced bladder cancer in the second line setting. Immune check point inhibitors have shown promising results in management of this disease. In this review we will discuss the recently evolving role of anti PD-1/PD-L1 inhibitors (programmed cell death protein-1 and programmed death ligand-1) for managing this disease.},
 year = {2017}
}

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TY  - JOUR
T1  - PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer
AU  - Samina Qamar
AU  - Uzair Bashir Chaudhary
Y1  - 2017/09/04
PY  - 2017
N1  - https://doi.org/10.11648/j.jctr.20170505.11
DO  - 10.11648/j.jctr.20170505.11
T2  - Journal of Cancer Treatment and Research
JF  - Journal of Cancer Treatment and Research
JO  - Journal of Cancer Treatment and Research
SP  - 71
EP  - 80
PB  - Science Publishing Group
SN  - 2376-7790
UR  - https://doi.org/10.11648/j.jctr.20170505.11
AB  - Advanced bladder cancer (BC) has a poor prognosis with historically limited therapeutic options. Immunotherapy has emerged as a viable option for patients with advanced bladder cancer in the second line setting. Immune check point inhibitors have shown promising results in management of this disease. In this review we will discuss the recently evolving role of anti PD-1/PD-L1 inhibitors (programmed cell death protein-1 and programmed death ligand-1) for managing this disease.
VL  - 5
IS  - 5
ER  -

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Author Information

Samina Qamar

Division of Geriatrics, Gerontology & Palliative medicine, University of Texas Health Science Center, San Antonio, USA
Uzair Bashir Chaudhary

Division of Hematology & Oncology, University of California San Francisco, Fresno, USA

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Samina Qamar, Uzair Bashir Chaudhary. (2017). PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer. Journal of Cancer Treatment and Research, 5(5), 71-80. https://doi.org/10.11648/j.jctr.20170505.11

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ACS Style

Samina Qamar; Uzair Bashir Chaudhary. PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer. J. Cancer Treat. Res. 2017, 5(5), 71-80. doi: 10.11648/j.jctr.20170505.11

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AMA Style

Samina Qamar, Uzair Bashir Chaudhary. PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer. J Cancer Treat Res. 2017;5(5):71-80. doi: 10.11648/j.jctr.20170505.11

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@article{10.11648/j.jctr.20170505.11,
  author = {Samina Qamar and Uzair Bashir Chaudhary},
  title = {PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer},
  journal = {Journal of Cancer Treatment and Research},
  volume = {5},
  number = {5},
  pages = {71-80},
  doi = {10.11648/j.jctr.20170505.11},
  url = {https://doi.org/10.11648/j.jctr.20170505.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20170505.11},
  abstract = {Advanced bladder cancer (BC) has a poor prognosis with historically limited therapeutic options. Immunotherapy has emerged as a viable option for patients with advanced bladder cancer in the second line setting. Immune check point inhibitors have shown promising results in management of this disease. In this review we will discuss the recently evolving role of anti PD-1/PD-L1 inhibitors (programmed cell death protein-1 and programmed death ligand-1) for managing this disease.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - PD1/PDL-1 Inhibitors: Emerging Hope for Bladder Cancer
AU  - Samina Qamar
AU  - Uzair Bashir Chaudhary
Y1  - 2017/09/04
PY  - 2017
N1  - https://doi.org/10.11648/j.jctr.20170505.11
DO  - 10.11648/j.jctr.20170505.11
T2  - Journal of Cancer Treatment and Research
JF  - Journal of Cancer Treatment and Research
JO  - Journal of Cancer Treatment and Research
SP  - 71
EP  - 80
PB  - Science Publishing Group
SN  - 2376-7790
UR  - https://doi.org/10.11648/j.jctr.20170505.11
AB  - Advanced bladder cancer (BC) has a poor prognosis with historically limited therapeutic options. Immunotherapy has emerged as a viable option for patients with advanced bladder cancer in the second line setting. Immune check point inhibitors have shown promising results in management of this disease. In this review we will discuss the recently evolving role of anti PD-1/PD-L1 inhibitors (programmed cell death protein-1 and programmed death ligand-1) for managing this disease.
VL  - 5
IS  - 5
ER  -

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