Cancer causes a great number of death every year in the world and has been destroying numerous happy families. Both the government and individuals spend vast sums of money on cancer, which makes cancer a great burden to the society. Due to its properties and therapeutic operations, patients with cancer are often accompany with anemia. Red blood cell (RBC) transfusion is a preferred symptomatic treatment strategy. But, considering side effects, optimal protocol of blood transfusion for cancer patients is still in air. Though much work has been done, there are still continuous arguments on the adverse effects of blood transfusion on cancer prognosis. By reviewing these works, we focused on the essential elements of transfusion, i.e. the time and dose of blood transfusion, as well as the type and source of blood product. Though we failed to find a definite answer, previous studies indicated some clues on the relationships between cancer prognosis and these elements. Transfusion prior to surgery and reduction of intraoperative and postoperative blood demand may be beneficial. As for RBC type, autologous leucocyte-depleted RBC might have priority. However, more high-quality randomized clinical trials are needed to settle those questions. Furtherly, this narrative review suggested some critical ideas on further studies.
| Published in | Journal of Cancer Treatment and Research (Volume 9, Issue 4) |
| DOI | 10.11648/j.jctr.20210904.12 |
| Page(s) | 63-66 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Blood Transfusion, Cancer, Prognosis
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APA Style
Rui Zhou, Liehong Yang, Ru Yu. (2021). Controversial Role of Blood Transfusion on Outcomes of Patients with Cancer: A Focused Review. Journal of Cancer Treatment and Research, 9(4), 63-66. https://doi.org/10.11648/j.jctr.20210904.12
ACS Style
Rui Zhou; Liehong Yang; Ru Yu. Controversial Role of Blood Transfusion on Outcomes of Patients with Cancer: A Focused Review. J. Cancer Treat. Res. 2021, 9(4), 63-66. doi: 10.11648/j.jctr.20210904.12
AMA Style
Rui Zhou, Liehong Yang, Ru Yu. Controversial Role of Blood Transfusion on Outcomes of Patients with Cancer: A Focused Review. J Cancer Treat Res. 2021;9(4):63-66. doi: 10.11648/j.jctr.20210904.12
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Download@article{10.11648/j.jctr.20210904.12,
author = {Rui Zhou and Liehong Yang and Ru Yu},
title = {Controversial Role of Blood Transfusion on Outcomes of Patients with Cancer: A Focused Review},
journal = {Journal of Cancer Treatment and Research},
volume = {9},
number = {4},
pages = {63-66},
doi = {10.11648/j.jctr.20210904.12},
url = {https://doi.org/10.11648/j.jctr.20210904.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20210904.12},
abstract = {Cancer causes a great number of death every year in the world and has been destroying numerous happy families. Both the government and individuals spend vast sums of money on cancer, which makes cancer a great burden to the society. Due to its properties and therapeutic operations, patients with cancer are often accompany with anemia. Red blood cell (RBC) transfusion is a preferred symptomatic treatment strategy. But, considering side effects, optimal protocol of blood transfusion for cancer patients is still in air. Though much work has been done, there are still continuous arguments on the adverse effects of blood transfusion on cancer prognosis. By reviewing these works, we focused on the essential elements of transfusion, i.e. the time and dose of blood transfusion, as well as the type and source of blood product. Though we failed to find a definite answer, previous studies indicated some clues on the relationships between cancer prognosis and these elements. Transfusion prior to surgery and reduction of intraoperative and postoperative blood demand may be beneficial. As for RBC type, autologous leucocyte-depleted RBC might have priority. However, more high-quality randomized clinical trials are needed to settle those questions. Furtherly, this narrative review suggested some critical ideas on further studies.},
year = {2021}
}
TY - JOUR T1 - Controversial Role of Blood Transfusion on Outcomes of Patients with Cancer: A Focused Review AU - Rui Zhou AU - Liehong Yang AU - Ru Yu Y1 - 2021/12/07 PY - 2021 N1 - https://doi.org/10.11648/j.jctr.20210904.12 DO - 10.11648/j.jctr.20210904.12 T2 - Journal of Cancer Treatment and Research JF - Journal of Cancer Treatment and Research JO - Journal of Cancer Treatment and Research SP - 63 EP - 66 PB - Science Publishing Group SN - 2376-7790 UR - https://doi.org/10.11648/j.jctr.20210904.12 AB - Cancer causes a great number of death every year in the world and has been destroying numerous happy families. Both the government and individuals spend vast sums of money on cancer, which makes cancer a great burden to the society. Due to its properties and therapeutic operations, patients with cancer are often accompany with anemia. Red blood cell (RBC) transfusion is a preferred symptomatic treatment strategy. But, considering side effects, optimal protocol of blood transfusion for cancer patients is still in air. Though much work has been done, there are still continuous arguments on the adverse effects of blood transfusion on cancer prognosis. By reviewing these works, we focused on the essential elements of transfusion, i.e. the time and dose of blood transfusion, as well as the type and source of blood product. Though we failed to find a definite answer, previous studies indicated some clues on the relationships between cancer prognosis and these elements. Transfusion prior to surgery and reduction of intraoperative and postoperative blood demand may be beneficial. As for RBC type, autologous leucocyte-depleted RBC might have priority. However, more high-quality randomized clinical trials are needed to settle those questions. Furtherly, this narrative review suggested some critical ideas on further studies. VL - 9 IS - 4 ER -
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