Over the years, traditional societies and ethnic nationalities have engaged plants with medicinal properties for the treatment of a range of diseases without any scientific knowledge of it inherent bioactive compounds that are responsible for its medicinal and pharmacological potentials. The aim of this study is to screen for the presence of phytochemical constituents and to identify the bioactive compounds domicile in the stem bark of Picralima nitida by the use of Gas Chromatography - Mass Spectrometry. The result of the quantitative investigation of the stem bark extract of P. nitida showed the presence of some phytochemical compounds such as saponins (3.22%), alkaloids (2.43%), flavonoids (6.05%) tannins (6.25%), oxalate (12.70%), phytate (2.87%), anthracene glycosides (2.14%) and cyanogenic glycosides (1.37%). Eleven (11) different bioactive compounds were recognized in the stem bark extract of P. nitida by Gas Chromatography - Mass Spectrometry analysis. The percentage of major bioactive compounds were vitamin E (69.31%), Cis-Myrtanol (5.57%), Octadecanoic acid methyl ester (4.52%), 11-Octadecenoic acid methyl ester (4.42%), 9-Methyl-2-phenyl-9H-imidazo (1,2-a) benzimidazole (3.70%), Pentadecanoic acid 14-methyl- methylester (3.21%) and 7,9-Dimethyl-6H-Indolo (2,3-b) quinoxaline (3.11%). From these findings, it could be concluded that P. nitida stem bark is rich in various bioactive compounds which possess antioxidant, laxative and other diverse medicinal properties. Therefore, it can be recommended as a plant of phytomedicinal value.
| Published in | Journal of Diseases and Medicinal Plants (Volume 10, Issue 1) |
| DOI | 10.11648/j.jdmp.20241001.12 |
| Page(s) | 8-16 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Phytochemical Constituents, Gas Chromatography - Mass Spectrometry Analysis, Picralima nitida, Bio-Active Compounds, Aqueous Extract
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APA Style
Onwuegbuchulam, C. H., Peter, D. A., Moses, O. I. (2024). Phytochemical Screening and Gas Chromatography-Mass Spectrometry Analysis of Bioactive Compounds Present in Stem Bark of Picralima nitida (stapf). Journal of Diseases and Medicinal Plants, 10(1), 8-16. https://doi.org/10.11648/j.jdmp.20241001.12
ACS Style
Onwuegbuchulam, C. H.; Peter, D. A.; Moses, O. I. Phytochemical Screening and Gas Chromatography-Mass Spectrometry Analysis of Bioactive Compounds Present in Stem Bark of Picralima nitida (stapf). J. Dis. Med. Plants 2024, 10(1), 8-16. doi: 10.11648/j.jdmp.20241001.12
AMA Style
Onwuegbuchulam CH, Peter DA, Moses OI. Phytochemical Screening and Gas Chromatography-Mass Spectrometry Analysis of Bioactive Compounds Present in Stem Bark of Picralima nitida (stapf). J Dis Med Plants. 2024;10(1):8-16. doi: 10.11648/j.jdmp.20241001.12
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Download@article{10.11648/j.jdmp.20241001.12,
author = {Chibuzo Henry Onwuegbuchulam and Dabesor Anani Peter and Olorunyolemi Imoleayo Moses},
title = {Phytochemical Screening and Gas Chromatography-Mass Spectrometry Analysis of Bioactive Compounds Present in Stem Bark of Picralima nitida (stapf)},
journal = {Journal of Diseases and Medicinal Plants},
volume = {10},
number = {1},
pages = {8-16},
doi = {10.11648/j.jdmp.20241001.12},
url = {https://doi.org/10.11648/j.jdmp.20241001.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20241001.12},
abstract = {Over the years, traditional societies and ethnic nationalities have engaged plants with medicinal properties for the treatment of a range of diseases without any scientific knowledge of it inherent bioactive compounds that are responsible for its medicinal and pharmacological potentials. The aim of this study is to screen for the presence of phytochemical constituents and to identify the bioactive compounds domicile in the stem bark of Picralima nitida by the use of Gas Chromatography - Mass Spectrometry. The result of the quantitative investigation of the stem bark extract of P. nitida showed the presence of some phytochemical compounds such as saponins (3.22%), alkaloids (2.43%), flavonoids (6.05%) tannins (6.25%), oxalate (12.70%), phytate (2.87%), anthracene glycosides (2.14%) and cyanogenic glycosides (1.37%). Eleven (11) different bioactive compounds were recognized in the stem bark extract of P. nitida by Gas Chromatography - Mass Spectrometry analysis. The percentage of major bioactive compounds were vitamin E (69.31%), Cis-Myrtanol (5.57%), Octadecanoic acid methyl ester (4.52%), 11-Octadecenoic acid methyl ester (4.42%), 9-Methyl-2-phenyl-9H-imidazo (1,2-a) benzimidazole (3.70%), Pentadecanoic acid 14-methyl- methylester (3.21%) and 7,9-Dimethyl-6H-Indolo (2,3-b) quinoxaline (3.11%). From these findings, it could be concluded that P. nitida stem bark is rich in various bioactive compounds which possess antioxidant, laxative and other diverse medicinal properties. Therefore, it can be recommended as a plant of phytomedicinal value.
},
year = {2024}
}
TY - JOUR T1 - Phytochemical Screening and Gas Chromatography-Mass Spectrometry Analysis of Bioactive Compounds Present in Stem Bark of Picralima nitida (stapf) AU - Chibuzo Henry Onwuegbuchulam AU - Dabesor Anani Peter AU - Olorunyolemi Imoleayo Moses Y1 - 2024/03/07 PY - 2024 N1 - https://doi.org/10.11648/j.jdmp.20241001.12 DO - 10.11648/j.jdmp.20241001.12 T2 - Journal of Diseases and Medicinal Plants JF - Journal of Diseases and Medicinal Plants JO - Journal of Diseases and Medicinal Plants SP - 8 EP - 16 PB - Science Publishing Group SN - 2469-8210 UR - https://doi.org/10.11648/j.jdmp.20241001.12 AB - Over the years, traditional societies and ethnic nationalities have engaged plants with medicinal properties for the treatment of a range of diseases without any scientific knowledge of it inherent bioactive compounds that are responsible for its medicinal and pharmacological potentials. The aim of this study is to screen for the presence of phytochemical constituents and to identify the bioactive compounds domicile in the stem bark of Picralima nitida by the use of Gas Chromatography - Mass Spectrometry. The result of the quantitative investigation of the stem bark extract of P. nitida showed the presence of some phytochemical compounds such as saponins (3.22%), alkaloids (2.43%), flavonoids (6.05%) tannins (6.25%), oxalate (12.70%), phytate (2.87%), anthracene glycosides (2.14%) and cyanogenic glycosides (1.37%). Eleven (11) different bioactive compounds were recognized in the stem bark extract of P. nitida by Gas Chromatography - Mass Spectrometry analysis. The percentage of major bioactive compounds were vitamin E (69.31%), Cis-Myrtanol (5.57%), Octadecanoic acid methyl ester (4.52%), 11-Octadecenoic acid methyl ester (4.42%), 9-Methyl-2-phenyl-9H-imidazo (1,2-a) benzimidazole (3.70%), Pentadecanoic acid 14-methyl- methylester (3.21%) and 7,9-Dimethyl-6H-Indolo (2,3-b) quinoxaline (3.11%). From these findings, it could be concluded that P. nitida stem bark is rich in various bioactive compounds which possess antioxidant, laxative and other diverse medicinal properties. Therefore, it can be recommended as a plant of phytomedicinal value. VL - 10 IS - 1 ER -
Department of Biochemistry, Wesley University Ondo, Ondo City, Nigeria
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