Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China

Qiong Dai; Xuejun Kong; Yiqing Song; Aiqin Zhou; Xuan Zhang; Ping Zhang; Minghui Li; Xinglian Liu; Jun Wang; Haiqing Xu

doi:doi:10.11648/j.jfmhc.20190504.15

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Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China

Qiong Dai, Xuejun Kong, Yiqing Song, Aiqin Zhou, Xuan Zhang, Ping Zhang, Minghui Li, Xinglian Liu, Jun Wang, Haiqing Xu

Published in Journal of Family Medicine and Health Care (Volume 5, Issue 4)

Received: 6 November 2019 Accepted: 22 November 2019 Published: 6 December 2019

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Abstract

We recruited 15,417 participants aged 18 to 36 months in central China using a stratified, multi-stage random sampling method. For children with a positive result in Toddlers screening test, further diagnostic assessment of autism spectrum disorders (ASD) was performed using the childhood autism rating scale and the Diagnostic and Statistical Manual of Mental Disorders. ASD prevalence among these children was 0.58% in Hubei province. Multivariate-adjusted logistic regression models were then used to explore potential ASD risk factors. One parent aged 35 or older, preterm birth, and birth weight < 2.0 kg remained significantly associated with elevated ASD risk (P < 0.05). These findings indicated that management of adverse perinatal factors may prevent the occurrence of ASD.

Published in	Journal of Family Medicine and Health Care (Volume 5, Issue 4)
DOI	10.11648/j.jfmhc.20190504.15
Page(s)	64-69
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Autism Spectrum Disorders, Prevalence, Risk Factors

References

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APA Style

Qiong Dai, Xuejun Kong, Yiqing Song, Aiqin Zhou, Xuan Zhang, et al. (2019). Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China. Journal of Family Medicine and Health Care, 5(4), 64-69. https://doi.org/10.11648/j.jfmhc.20190504.15

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ACS Style

Qiong Dai; Xuejun Kong; Yiqing Song; Aiqin Zhou; Xuan Zhang, et al. Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China. J. Fam. Med. Health Care 2019, 5(4), 64-69. doi: 10.11648/j.jfmhc.20190504.15

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AMA Style

Qiong Dai, Xuejun Kong, Yiqing Song, Aiqin Zhou, Xuan Zhang, et al. Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China. J Fam Med Health Care. 2019;5(4):64-69. doi: 10.11648/j.jfmhc.20190504.15

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@article{10.11648/j.jfmhc.20190504.15,
  author = {Qiong Dai and Xuejun Kong and Yiqing Song and Aiqin Zhou and Xuan Zhang and Ping Zhang and Minghui Li and Xinglian Liu and Jun Wang and Haiqing Xu},
  title = {Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China},
  journal = {Journal of Family Medicine and Health Care},
  volume = {5},
  number = {4},
  pages = {64-69},
  doi = {10.11648/j.jfmhc.20190504.15},
  url = {https://doi.org/10.11648/j.jfmhc.20190504.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20190504.15},
  abstract = {We recruited 15,417 participants aged 18 to 36 months in central China using a stratified, multi-stage random sampling method. For children with a positive result in Toddlers screening test, further diagnostic assessment of autism spectrum disorders (ASD) was performed using the childhood autism rating scale and the Diagnostic and Statistical Manual of Mental Disorders. ASD prevalence among these children was 0.58% in Hubei province. Multivariate-adjusted logistic regression models were then used to explore potential ASD risk factors. One parent aged 35 or older, preterm birth, and birth weight P < 0.05). These findings indicated that management of adverse perinatal factors may prevent the occurrence of ASD.},
 year = {2019}
}

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TY  - JOUR
T1  - Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China
AU  - Qiong Dai
AU  - Xuejun Kong
AU  - Yiqing Song
AU  - Aiqin Zhou
AU  - Xuan Zhang
AU  - Ping Zhang
AU  - Minghui Li
AU  - Xinglian Liu
AU  - Jun Wang
AU  - Haiqing Xu
Y1  - 2019/12/06
PY  - 2019
N1  - https://doi.org/10.11648/j.jfmhc.20190504.15
DO  - 10.11648/j.jfmhc.20190504.15
T2  - Journal of Family Medicine and Health Care
JF  - Journal of Family Medicine and Health Care
JO  - Journal of Family Medicine and Health Care
SP  - 64
EP  - 69
PB  - Science Publishing Group
SN  - 2469-8342
UR  - https://doi.org/10.11648/j.jfmhc.20190504.15
AB  - We recruited 15,417 participants aged 18 to 36 months in central China using a stratified, multi-stage random sampling method. For children with a positive result in Toddlers screening test, further diagnostic assessment of autism spectrum disorders (ASD) was performed using the childhood autism rating scale and the Diagnostic and Statistical Manual of Mental Disorders. ASD prevalence among these children was 0.58% in Hubei province. Multivariate-adjusted logistic regression models were then used to explore potential ASD risk factors. One parent aged 35 or older, preterm birth, and birth weight P < 0.05). These findings indicated that management of adverse perinatal factors may prevent the occurrence of ASD.
VL  - 5
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Author Information

Qiong Dai

Health Care Department, Maternal and Child Health Hospital of Hubei Province, Huazhong University of Science and Technology, Wuhan, China
Xuejun Kong

Synapse Program/Martinos Center, Massachusetts General Hospital, Harvard Medical School, Bostons, USA
Yiqing Song

Department of Epidemiology, School of Public Health, University of Indiana, Bloomington, USA
Aiqin Zhou

Health Care Department, Maternal and Child Health Hospital of Hubei Province, Huazhong University of Science and Technology, Wuhan, China
Xuan Zhang

Health Care Department, Maternal and Child Health Hospital of Hubei Province, Huazhong University of Science and Technology, Wuhan, China
Ping Zhang

Health Care Department, Maternal and Child Health Hospital of Hubei Province, Huazhong University of Science and Technology, Wuhan, China
Minghui Li

Health Care Department, Maternal and Child Health Hospital of Hubei Province, Huazhong University of Science and Technology, Wuhan, China
Xinglian Liu

Health Care Department, Maternal and Child Health Hospital of Hubei Province, Huazhong University of Science and Technology, Wuhan, China
Jun Wang

Department of Biomedicine and Biopharmaceuticals, Hubei University of Technology, Wuhan, China
Haiqing Xu

Health Care Department, Maternal and Child Health Hospital of Hubei Province, Huazhong University of Science and Technology, Wuhan, China

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APA Style

Qiong Dai, Xuejun Kong, Yiqing Song, Aiqin Zhou, Xuan Zhang, et al. (2019). Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China. Journal of Family Medicine and Health Care, 5(4), 64-69. https://doi.org/10.11648/j.jfmhc.20190504.15

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ACS Style

Qiong Dai; Xuejun Kong; Yiqing Song; Aiqin Zhou; Xuan Zhang, et al. Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China. J. Fam. Med. Health Care 2019, 5(4), 64-69. doi: 10.11648/j.jfmhc.20190504.15

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AMA Style

Qiong Dai, Xuejun Kong, Yiqing Song, Aiqin Zhou, Xuan Zhang, et al. Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China. J Fam Med Health Care. 2019;5(4):64-69. doi: 10.11648/j.jfmhc.20190504.15

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@article{10.11648/j.jfmhc.20190504.15,
  author = {Qiong Dai and Xuejun Kong and Yiqing Song and Aiqin Zhou and Xuan Zhang and Ping Zhang and Minghui Li and Xinglian Liu and Jun Wang and Haiqing Xu},
  title = {Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China},
  journal = {Journal of Family Medicine and Health Care},
  volume = {5},
  number = {4},
  pages = {64-69},
  doi = {10.11648/j.jfmhc.20190504.15},
  url = {https://doi.org/10.11648/j.jfmhc.20190504.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20190504.15},
  abstract = {We recruited 15,417 participants aged 18 to 36 months in central China using a stratified, multi-stage random sampling method. For children with a positive result in Toddlers screening test, further diagnostic assessment of autism spectrum disorders (ASD) was performed using the childhood autism rating scale and the Diagnostic and Statistical Manual of Mental Disorders. ASD prevalence among these children was 0.58% in Hubei province. Multivariate-adjusted logistic regression models were then used to explore potential ASD risk factors. One parent aged 35 or older, preterm birth, and birth weight P < 0.05). These findings indicated that management of adverse perinatal factors may prevent the occurrence of ASD.},
 year = {2019}
}

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TY  - JOUR
T1  - Prevalence and Risk Factors of Autism Spectrum Disorders in Children Aged 18-36 Months in Hubei Province, China
AU  - Qiong Dai
AU  - Xuejun Kong
AU  - Yiqing Song
AU  - Aiqin Zhou
AU  - Xuan Zhang
AU  - Ping Zhang
AU  - Minghui Li
AU  - Xinglian Liu
AU  - Jun Wang
AU  - Haiqing Xu
Y1  - 2019/12/06
PY  - 2019
N1  - https://doi.org/10.11648/j.jfmhc.20190504.15
DO  - 10.11648/j.jfmhc.20190504.15
T2  - Journal of Family Medicine and Health Care
JF  - Journal of Family Medicine and Health Care
JO  - Journal of Family Medicine and Health Care
SP  - 64
EP  - 69
PB  - Science Publishing Group
SN  - 2469-8342
UR  - https://doi.org/10.11648/j.jfmhc.20190504.15
AB  - We recruited 15,417 participants aged 18 to 36 months in central China using a stratified, multi-stage random sampling method. For children with a positive result in Toddlers screening test, further diagnostic assessment of autism spectrum disorders (ASD) was performed using the childhood autism rating scale and the Diagnostic and Statistical Manual of Mental Disorders. ASD prevalence among these children was 0.58% in Hubei province. Multivariate-adjusted logistic regression models were then used to explore potential ASD risk factors. One parent aged 35 or older, preterm birth, and birth weight P < 0.05). These findings indicated that management of adverse perinatal factors may prevent the occurrence of ASD.
VL  - 5
IS  - 4
ER  -

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