Research Article | | Peer-Reviewed

Antibiotic Prophylaxis During Cesarean Section in the Gynecology-Obstetrics Department of the Donka National Hospital, Conakry

Received: 12 February 2025     Accepted: 24 February 2025     Published: 6 March 2025
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Abstract

Objective: To evaluate the effectiveness of antibiotic prophylaxis during cesarean section in the Gynecology-Obstetrics department of the Donka national hospital in Conakry. Methodology: This was a prospective case-control analytical study lasting 3 months involving 250 patients undergoing cesarean section. The short protocol included 125 patients who received a single dose of 2g of antibiotics intraoperatively after cord clamping while the other 125 patients (long protocol) received antibiotic therapy for 48 hours after the procedure. Results: The sociodemographic profile of the patients was the same in both arms. The mean age of the patients was 24 years with extremes of 14 and 42 years; the 20-24 age group was the most represented (31.2% vs 32.8%). Our series was dominated by primiparas (40% vs 42%). The main mode of admission was evacuation (78.4% vs 64%). The main early postoperative complication encountered was fever (8.2% vs 13.2%) followed by surgical site infection (4% vs 12%). Bivariate analysis shows a statistically significant association between the occurrence of postoperative fever and the long antibiotic protocol (p = 0.028) and this protocol is a protective factor against surgical site infection (p = 0.013). And is more frequently used in the context of emergency cesarean section (p = 0.011). Conclusion: Antibiotic prophylaxis is as effective as antibiotic therapy and thus represents a significant health saving for our countries.

Published in Journal of Gynecology and Obstetrics (Volume 13, Issue 2)
DOI 10.11648/j.jgo.20251302.11
Page(s) 17-21
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Antibiotic Prophylaxis, Antibiotic Therapy, Cesarean Section, Conakry

References
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[2] Ghoro A, Toure-Ecra F, Fanny M, Seni K, Konan Ble R, Quenum G, Sissoko M, Sawadogo D, Faye-Kette H, Kone M, Welffens-Ekra C. Antibiotic prophylaxis in cesarean sections at the Yopougon University Hospital (Abidjan). Black African Medicine. 2004; 51(12): 659-663.
[3] Rambourdin M, Bonnin M, Storme B, Brunhes A, Boeuf B, Kauffmann S, Pinheiro H, Vernis L, Lavergne B, Gallot D, Vendittelli F. Antibiotic prophylaxis for cesarean section: modification of practices and administration before incision, feasibility survey among pediatricians of the Auvergne perinatal health network (RSPA). French annals of anesthesia and resuscitation. Elsevier Masson. 2013; 32(1): 12-17.
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[5] Racinet C, Mallaret Mr, Favier M, Berthet J, Morel I, Fauconnier J. Antibiotic prophylaxis in cesarean sections without high risk of infection: therapeutic trial of cefotetan versus placebo. La Presse médicale (1983). 1990; 19(38): 1755-1758.
[6] Malavaud S, Bou-Segonds E, Berrebi A, Castagno R, Assouline C, Connan L. Nosocomial infections in mothers and children: a report on an incidence survey of 804 deliveries. Journal of Gynecology, Obstetrics and Reproductive Biology. 2003; 32(2): 169-174.
[7] Pambou O, Coulon F, Neveu C, Tadjerouni A, Tribalat S. Controlling caesarean-site infection. Collaboration between the obstetric and hospital hygiene departments. Health. 2011; 21(4): 205-8.
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[9] World Health Organization. Managing complications in pregnancy and childbirth: a guide for midwives and doctors. 2002: C35-6.
[10] Aulakh A, Idoko P, Anderson ST, Graham W. Caesarean section wound infections and antibiotic use: a retrospective case-series in a tertiary referral hospital in The Gambia. Too Doct. 2018 Jul; 48(3): 192-199.
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[12] Assawapalanggool S, Kasatpibal N, Sirichotiyakul S, Arora R, Suntornlimsiri W. Risk factors for cesarean surgical site infections at a Thai-Myanmar border hospital. Am J Infect Control. 2016; 44(9): 990-5.
[13] Lomangisi D Dlamini, Musa Sekikubo, Janat Tumukunde, Charles Kojjo, Davidson Ocen, Agnes Wabule et al. Antibiotic prophylaxis for caesarean section at a Ugandan hospital: a randomized clinical trial evaluating the effect of administration time on the incidence of postoperative infections. BMC Pregnancy and Childbirth. 2015; 15: 91.
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Cite This Article
  • APA Style

    Bah, I. K., Sow, A. I., Diallo, B. A., Tolno, J. T., Diallo, L., et al. (2025). Antibiotic Prophylaxis During Cesarean Section in the Gynecology-Obstetrics Department of the Donka National Hospital, Conakry. Journal of Gynecology and Obstetrics, 13(2), 17-21. https://doi.org/10.11648/j.jgo.20251302.11

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    ACS Style

    Bah, I. K.; Sow, A. I.; Diallo, B. A.; Tolno, J. T.; Diallo, L., et al. Antibiotic Prophylaxis During Cesarean Section in the Gynecology-Obstetrics Department of the Donka National Hospital, Conakry. J. Gynecol. Obstet. 2025, 13(2), 17-21. doi: 10.11648/j.jgo.20251302.11

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    AMA Style

    Bah IK, Sow AI, Diallo BA, Tolno JT, Diallo L, et al. Antibiotic Prophylaxis During Cesarean Section in the Gynecology-Obstetrics Department of the Donka National Hospital, Conakry. J Gynecol Obstet. 2025;13(2):17-21. doi: 10.11648/j.jgo.20251302.11

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  • @article{10.11648/j.jgo.20251302.11,
      author = {Ibrahima Koussy Bah and Alhassane II Sow and Boubacar Alpha Diallo and Julien Tamba Tolno and Laouratou Diallo and Maimouna Balde and Alpha Ibrahima Balde and Kabinet Camara and Abdourahamane Diallo and Telly Sy},
      title = {Antibiotic Prophylaxis During Cesarean Section in the Gynecology-Obstetrics Department of the Donka National Hospital, Conakry
    },
      journal = {Journal of Gynecology and Obstetrics},
      volume = {13},
      number = {2},
      pages = {17-21},
      doi = {10.11648/j.jgo.20251302.11},
      url = {https://doi.org/10.11648/j.jgo.20251302.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jgo.20251302.11},
      abstract = {Objective: To evaluate the effectiveness of antibiotic prophylaxis during cesarean section in the Gynecology-Obstetrics department of the Donka national hospital in Conakry. Methodology: This was a prospective case-control analytical study lasting 3 months involving 250 patients undergoing cesarean section. The short protocol included 125 patients who received a single dose of 2g of antibiotics intraoperatively after cord clamping while the other 125 patients (long protocol) received antibiotic therapy for 48 hours after the procedure. Results: The sociodemographic profile of the patients was the same in both arms. The mean age of the patients was 24 years with extremes of 14 and 42 years; the 20-24 age group was the most represented (31.2% vs 32.8%). Our series was dominated by primiparas (40% vs 42%). The main mode of admission was evacuation (78.4% vs 64%). The main early postoperative complication encountered was fever (8.2% vs 13.2%) followed by surgical site infection (4% vs 12%). Bivariate analysis shows a statistically significant association between the occurrence of postoperative fever and the long antibiotic protocol (p = 0.028) and this protocol is a protective factor against surgical site infection (p = 0.013). And is more frequently used in the context of emergency cesarean section (p = 0.011). Conclusion: Antibiotic prophylaxis is as effective as antibiotic therapy and thus represents a significant health saving for our countries.
    },
     year = {2025}
    }
    

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  • TY  - JOUR
    T1  - Antibiotic Prophylaxis During Cesarean Section in the Gynecology-Obstetrics Department of the Donka National Hospital, Conakry
    
    AU  - Ibrahima Koussy Bah
    AU  - Alhassane II Sow
    AU  - Boubacar Alpha Diallo
    AU  - Julien Tamba Tolno
    AU  - Laouratou Diallo
    AU  - Maimouna Balde
    AU  - Alpha Ibrahima Balde
    AU  - Kabinet Camara
    AU  - Abdourahamane Diallo
    AU  - Telly Sy
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    DO  - 10.11648/j.jgo.20251302.11
    T2  - Journal of Gynecology and Obstetrics
    JF  - Journal of Gynecology and Obstetrics
    JO  - Journal of Gynecology and Obstetrics
    SP  - 17
    EP  - 21
    PB  - Science Publishing Group
    SN  - 2376-7820
    UR  - https://doi.org/10.11648/j.jgo.20251302.11
    AB  - Objective: To evaluate the effectiveness of antibiotic prophylaxis during cesarean section in the Gynecology-Obstetrics department of the Donka national hospital in Conakry. Methodology: This was a prospective case-control analytical study lasting 3 months involving 250 patients undergoing cesarean section. The short protocol included 125 patients who received a single dose of 2g of antibiotics intraoperatively after cord clamping while the other 125 patients (long protocol) received antibiotic therapy for 48 hours after the procedure. Results: The sociodemographic profile of the patients was the same in both arms. The mean age of the patients was 24 years with extremes of 14 and 42 years; the 20-24 age group was the most represented (31.2% vs 32.8%). Our series was dominated by primiparas (40% vs 42%). The main mode of admission was evacuation (78.4% vs 64%). The main early postoperative complication encountered was fever (8.2% vs 13.2%) followed by surgical site infection (4% vs 12%). Bivariate analysis shows a statistically significant association between the occurrence of postoperative fever and the long antibiotic protocol (p = 0.028) and this protocol is a protective factor against surgical site infection (p = 0.013). And is more frequently used in the context of emergency cesarean section (p = 0.011). Conclusion: Antibiotic prophylaxis is as effective as antibiotic therapy and thus represents a significant health saving for our countries.
    
    VL  - 13
    IS  - 2
    ER  - 

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Author Information
  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

  • Gynecology-obstetrics Department, Donka National Hospital, Conakry, Guinea

  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

  • Gynecology-Obstetrics Department, Ignace Deen National Hospital, Conakry, Guinea

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