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Seminoma Arising from Cryptorchidism Presenting as a Giant Extraperitoneal Abdominal Mass: A Case Report

Received: 2 April 2023    Accepted: 24 April 2023    Published: 10 May 2023
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Abstract

Background: Preperitoneum cryptorchidism is infrequent in adults, and has an extremely high risk of malignant transformation. The diagnosis requires a comprehensive consideration of symptoms, findings upon physical examination, and laboratory and imaging tests. Case information: We report a case of a 38-year-old man with a massive abdominal mass corresponding to a seminoma arising from cryptorchidism. Contrast-enhanced computer tomography demonstrated a large mass with clear realm and uneven density. The testicular artery was found to originate from the left iliac fossa, and could be traced back to the abdominal aorta. The left spermatic cord was not present within the inguinal canal. Result: Laparotomy was performed with midline incision, and we did not enter the abdominal cavity, wherein a large solid mass was identified in the preperitoneum, with the vascular pedicle originating in the left iliac fossa. The mass was resected en bloc. The pathological evaluation of the resected specimen was compatible with seminoma. The patient was referred to the department of oncology after discharge. The patient completed four cycles of etoposide/cisplatin adjuvant chemotherapy. The five-year follow-up showed no evidence of local or distant disease recurrence. Conclusions: Malignant transformation of cryptorchidism can present as an abdominal mass, and clinicians must be aware of this possibility, in order to provide opportune diagnosis.

Published in Journal of Surgery (Volume 11, Issue 2)
DOI 10.11648/j.js.20231102.15
Page(s) 60-63
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Cryptorchidism, Seminoma, Abdominal Mass, Case Report

References
[1] Dieckmann KP, Richter-Simonsen H, Kulejewski M, et al: Testicular Germ-Cell Tumours: A Descriptive Analysis of Clinical Characteristics at First Presentation. Urol Int 100 (4): 409-419, 2018.
[2] Wood HM and Elder JS: Cryptorchidism and testicular cancer: separating fact from fiction. J Urol 181 (2): 452-461, 2009.
[3] Faruk M, Palinrungi MA, Kholis K, et al. A giant intra-abdominal right testicular seminoma in a bilateral undescended testicle: a case report. Pan Afr Med J 44: 3, 2023.
[4] Nickalls OJ, Tan CL and Thian Y: A Torted Ruptured Intra-abdominal Testicular Seminoma Presenting As An Acute Abdomen. J Radiol Case Rep 9 (12): 21-28, 2015.
[5] Sushma Agrawal, Ranjeet Bajpai, R. K. Agrawal, et al: Bilateral synchronous seminoma with bilateral cryptorchidism of the testis. Indian J Urol 26 (4): 587-589, 2010.
[6] Nkembe M. N., Mvalo C. M., Tianyi F. L., Demba C. Ambiguous presentation of an intra-abdominal testicular seminoma in a 40-year-old man: a case report. J Med Case Rep 13 (1): 1–4, 2019.
[7] Parajuli P., Man Pradhan M., Chapagain S., Luitel B. R., Chalise P. R., Sharma U. K. Intra-abdominal mass with empty scrotum in adult male. Urol Case Rep 34, 2021.
[8] Wong DG, Singla N, Bagrodia A. Massive Intra-abdominal Germ Cell Tumors: A Case Series and Review of Literature. Rev Urol 21 (2-3): 136-140, 2019.
[9] 7, Zhou JL, Liu DQ, Lei JX, et al. Abdominal cocoon syndrome with unilateral cryptorchidism and seminoma: A case report. Asian J Surg. 46 (2): 878-879, 2023.
[10] Ben Hadj Alouane H, Mrad Dali K, Madani MA, et al. Unusual presentation of an intra-abdominal testicular seminoma in an adult. Urol Case Rep 43: 102119, 2022.
[11] Sabbah BN, Alathel A, Alghafees MA, et al. Classical Seminoma With Secondary Undescended Testis in an Elderly Patient: An Incidental Finding With a Penile Fracture. Cureus 14 (11): e31924, 2022.
[12] Liu R, Li J, Jiang Y, et al. Apparent diffusion coefficient values of cryptorchid testes and malignant transformation of cryptorchidism (MTC) (seminoma) in postpubertal patients. Br J Radiol 94 (1119): 20200624, 2021.
[13] Zhu JL, Roberts MJ, Navaratnam A, et al: Bloating due to massive seminoma in an undescended testis. ANZ J Surg 89 (4): E160-E161, 2019.
[14] Pedrazzoli P, Rosti G, Soresini E, Ciani S, Secondino S. Serum tumour markers in germ cell tumours: From diagnosis to cure. Crit Rev Oncol Hematol 159: 103224, 2021.
[15] Miyai K, Yonekura Y, Ito K, Matsukuma S, Tsuda H. Gene expression microarray analysis of adult testicular germ cell tumor: a comparison between pure-type seminomas and seminoma components in mixed tumors. Virchows Arch 479 (6): 1177-1186, 2021.
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  • APA Style

    Cheng-Kai Xia, Xiao-Yang Wu. (2023). Seminoma Arising from Cryptorchidism Presenting as a Giant Extraperitoneal Abdominal Mass: A Case Report. Journal of Surgery, 11(2), 60-63. https://doi.org/10.11648/j.js.20231102.15

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    ACS Style

    Cheng-Kai Xia; Xiao-Yang Wu. Seminoma Arising from Cryptorchidism Presenting as a Giant Extraperitoneal Abdominal Mass: A Case Report. J. Surg. 2023, 11(2), 60-63. doi: 10.11648/j.js.20231102.15

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    AMA Style

    Cheng-Kai Xia, Xiao-Yang Wu. Seminoma Arising from Cryptorchidism Presenting as a Giant Extraperitoneal Abdominal Mass: A Case Report. J Surg. 2023;11(2):60-63. doi: 10.11648/j.js.20231102.15

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  • @article{10.11648/j.js.20231102.15,
      author = {Cheng-Kai Xia and Xiao-Yang Wu},
      title = {Seminoma Arising from Cryptorchidism Presenting as a Giant Extraperitoneal Abdominal Mass: A Case Report},
      journal = {Journal of Surgery},
      volume = {11},
      number = {2},
      pages = {60-63},
      doi = {10.11648/j.js.20231102.15},
      url = {https://doi.org/10.11648/j.js.20231102.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20231102.15},
      abstract = {Background: Preperitoneum cryptorchidism is infrequent in adults, and has an extremely high risk of malignant transformation. The diagnosis requires a comprehensive consideration of symptoms, findings upon physical examination, and laboratory and imaging tests. Case information: We report a case of a 38-year-old man with a massive abdominal mass corresponding to a seminoma arising from cryptorchidism. Contrast-enhanced computer tomography demonstrated a large mass with clear realm and uneven density. The testicular artery was found to originate from the left iliac fossa, and could be traced back to the abdominal aorta. The left spermatic cord was not present within the inguinal canal. Result: Laparotomy was performed with midline incision, and we did not enter the abdominal cavity, wherein a large solid mass was identified in the preperitoneum, with the vascular pedicle originating in the left iliac fossa. The mass was resected en bloc. The pathological evaluation of the resected specimen was compatible with seminoma. The patient was referred to the department of oncology after discharge. The patient completed four cycles of etoposide/cisplatin adjuvant chemotherapy. The five-year follow-up showed no evidence of local or distant disease recurrence. Conclusions: Malignant transformation of cryptorchidism can present as an abdominal mass, and clinicians must be aware of this possibility, in order to provide opportune diagnosis.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Seminoma Arising from Cryptorchidism Presenting as a Giant Extraperitoneal Abdominal Mass: A Case Report
    AU  - Cheng-Kai Xia
    AU  - Xiao-Yang Wu
    Y1  - 2023/05/10
    PY  - 2023
    N1  - https://doi.org/10.11648/j.js.20231102.15
    DO  - 10.11648/j.js.20231102.15
    T2  - Journal of Surgery
    JF  - Journal of Surgery
    JO  - Journal of Surgery
    SP  - 60
    EP  - 63
    PB  - Science Publishing Group
    SN  - 2330-0930
    UR  - https://doi.org/10.11648/j.js.20231102.15
    AB  - Background: Preperitoneum cryptorchidism is infrequent in adults, and has an extremely high risk of malignant transformation. The diagnosis requires a comprehensive consideration of symptoms, findings upon physical examination, and laboratory and imaging tests. Case information: We report a case of a 38-year-old man with a massive abdominal mass corresponding to a seminoma arising from cryptorchidism. Contrast-enhanced computer tomography demonstrated a large mass with clear realm and uneven density. The testicular artery was found to originate from the left iliac fossa, and could be traced back to the abdominal aorta. The left spermatic cord was not present within the inguinal canal. Result: Laparotomy was performed with midline incision, and we did not enter the abdominal cavity, wherein a large solid mass was identified in the preperitoneum, with the vascular pedicle originating in the left iliac fossa. The mass was resected en bloc. The pathological evaluation of the resected specimen was compatible with seminoma. The patient was referred to the department of oncology after discharge. The patient completed four cycles of etoposide/cisplatin adjuvant chemotherapy. The five-year follow-up showed no evidence of local or distant disease recurrence. Conclusions: Malignant transformation of cryptorchidism can present as an abdominal mass, and clinicians must be aware of this possibility, in order to provide opportune diagnosis.
    VL  - 11
    IS  - 2
    ER  - 

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Author Information
  • Department of Gastrointestinal Surgery, Kunshan First People’s Hospital Affiliated to Jiangsu University, Kunshan, China

  • Department of Gastrointestinal Surgery, Kunshan First People’s Hospital Affiliated to Jiangsu University, Kunshan, China

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