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Research Article
Precancerous Lesions of the Cervix: Screening and Management at the Matam Maternity Hospital and the Donka Gynaecological Cancer Prevention Centre (Guinea)
Conté Ibrahima*,
Kouyaté Sekouba,
Leno Daniel William Atanase,
Diallo Thierno Ibrahima,
Sow Alhassane Mohamed,
Diallo Yaya,
Sy Telly,
Hyjazi Yolande,
Keita Namory
Issue:
Volume 8, Issue 4, December 2023
Pages:
83-87
Received:
25 October 2023
Accepted:
11 November 2023
Published:
21 November 2023
Abstract: Introduction: Screening consists of the presumptive identification, by means of tests applied in a systematic and standardised manner, of subjects suffering from a disease or abnormality that has previously gone unnoticed. The aim of this work was to contribute to the study of screening and management of precancerous lesions of the cervix in women seen at the centres. Patients and methods: This was a prospective, descriptive study lasting twelve (12) months from 17/09/2020 to 16/09/202. It concerned all women seen for screening for precancerous lesions of the cervix during the period and who had agreed to participate voluntarily in the study. Results: screening for precancerous and cancerous lesions of the cervix was carried out in 35.06% of the women seen during the study period, and precancerous lesions were detected by VIA in 9.60% of them. Most of the women were aged between 31 and 39, with an average age of 36, married (86.66%), not in education (60.66%), had a liberal profession (55.46%) as their main occupation and were multiparous (37.26%). Screening and vaginal bleeding were the main reasons for consultation. Of the women screened positive for VIA, 218 had undergone cryotherapy and 26 had undergone loop electrosurgical resection. All had a favourable outcome. Conclusion: Cervical cancer is a major public health problem in developing countries such as Guinea. This study demonstrated the effectiveness of screening and management of precancerous lesions in the secondary prevention of cervical cancer.
Abstract: Introduction: Screening consists of the presumptive identification, by means of tests applied in a systematic and standardised manner, of subjects suffering from a disease or abnormality that has previously gone unnoticed. The aim of this work was to contribute to the study of screening and management of precancerous lesions of the cervix in women ...
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Research Article
Epidemiological, Diagnostic, Therapeutic and Evolutionary Profile of Inflammatory Breast Cancer (IBC) in the Oncology-Hematology Service, Burkina Faso
Bambara Hierrhum Aboubacar*,
Zoure Abdou Azaque,
Zerbo Nina Assanatou Jumelle,
Yameogo Prisca Emmanuelle Aida,
Adico Marc Donald Wilfried,
Odero-Marah Valérie
Issue:
Volume 8, Issue 4, December 2023
Pages:
88-93
Received:
9 November 2023
Accepted:
24 November 2023
Published:
6 December 2023
Abstract: Introduction: Inflammatory breast cancer (IBC) represents a particular clinical entity characterized by its rarity, rapid evolutionary pace and pejorative prognosis. This was a retrospective descriptive study from January 01, 2020 to June 30, 2022 in the clinical oncology-hematology service of CHU B. This study included 62 patients with inflammatory breast cancer. The diagnosis of IBC was clinical as defined by the American Joint Cancer Committee (AJCC) with a diagnosis of anatomopathological confirmation. IBC accounted for 37.57% of breast cancers reported during our study period. The average age of patients was 47 years. The age range of [40 years-50] represented 37.09% followed by those of [50 years-60 years] and [60 years-70] with each 19.35%. The average consultation time was 12 months. Signs of inflammation were found in all patients followed by the presence of nodules during clinical examination. Infiltrating ductal carcinoma accounted for 95% of cases followed by infiltrating lobular carcinoma in 3%. Modified Scarff Bloom Richardson grade II (mSBR) was encountered in 93.5% of cases followed by mSBR grade III with 6.5%. Only 11 patients (17.74%) were able to perform immunohistochemistry. Thus, the results found 43% and 23% respectively of type luminal A and luminal B and 23% classified type Triple negative. Chemotherapy was performed in 51 patients (82.25%) and was palliative in 32 patients (62.74%). Ten (10) patients underwent surgery including 9 mastectomies with axillary dissection (90%). Radiotherapy was performed in 02 patients (3.22%). Median survival was 05 months and overall survival at 12 months was 23%. Finally, IBC is a fairly common pathology according to this study and affects especially young women under 50 years. Its management is complex by the fact that specific examinations and anti-cancer are difficult to access.
Abstract: Introduction: Inflammatory breast cancer (IBC) represents a particular clinical entity characterized by its rarity, rapid evolutionary pace and pejorative prognosis. This was a retrospective descriptive study from January 01, 2020 to June 30, 2022 in the clinical oncology-hematology service of CHU B. This study included 62 patients with inflammator...
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Research Article
Prognostic Factors for Prostate Cancer at the Brazzaville University Hospital Center
Bambara Hierrhum Aboubacar*,
Zerbo Nina Assanatou Jumelle,
Odero-Marah Valérie,
Nkoua Epala Brice Aymard,
Nsonde Malanda Judith,
Nkoua-Mbon Jean-Bernard
Issue:
Volume 8, Issue 4, December 2023
Pages:
94-100
Received:
9 November 2023
Accepted:
24 November 2023
Published:
6 December 2023
Abstract: Second cancer frequently diagnosed in men; prostate cancer is responsible for high mortality. His prognosis has benefited from significant technical improvements. Determining prognostic factors in prostate cancer is an integral part of the therapeutic decision-making process. The aim of this study was to determine the prognostic factors of prostate cancer in the cancer department of University Hospital of Brazzaville in Congo. This was a retrospective descriptive study, which took place from 1 January 2016 to 31 December 2020, in the cancer department of the University Hospital of Brazzaville in Congo. During the study period, 118 files were retained. The survival curves were realized according to the Kaplan-Meier model, and the statistical comparison according to the Log-Rank model. The significance threshold was set at 5%. The results found that mean age was 68 ± 7.74 years. Low urinary tract symptoms accounted for 68.64% of the discovery circumstances. The Initial PSA was greater than 100 ng/ml in 65.25% of patients. Metastases were found in 95.76% of patients. Overall survival at 3 years was 15%. Survival differed significantly by age (p = 0.0017); WHO performance status (p = 0.0000); clinical stage (p = 0.0000) and metastatic site (p = 0.0022). Finally, the incidence of prostate cancer is increasing worldwide, hence the interest of defining a screening strategy, allowing to institute management with better results.
Abstract: Second cancer frequently diagnosed in men; prostate cancer is responsible for high mortality. His prognosis has benefited from significant technical improvements. Determining prognostic factors in prostate cancer is an integral part of the therapeutic decision-making process. The aim of this study was to determine the prognostic factors of prostate...
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Research Article
Epidemiological, Diagnostic and Evolutionary Profile of Stomach Cancer at Bogodogo University Hospital (Chub) in Ouagadougou (Burkina Faso)
Bambara Hierrhum Aboubacar*,
Zerbo Nina Assanatou Jumelle,
Kouraogo SoniaYasmina,
Coulibaly Aboubacar,
Zida Maurice
Issue:
Volume 8, Issue 4, December 2023
Pages:
101-106
Received:
27 November 2023
Accepted:
11 December 2023
Published:
22 December 2023
Abstract: Introduction: According to WHO estimates, in 2020 there will be over 1.1 million cases of stomach cancer, including 770,000 deaths, and it remains the third leading cause of cancer deaths worldwide. In Burkina Faso, Zoungrana et al. (2021) noted that stomach cancer ranked second among digestive cancers, with a prevalence of 74.28%. The aim of our study was to determine the epidemiological, diagnostic and evolutionary profile of stomach cancer in Ouagadougou. Patients and methods: This was a retrospective and descriptive study carried out in the Oncology and Clinical Hematology Department of CHUB in Ouagadougou from January 1, 2018 to December 31, 2022. We included in our study all patients who presented a stomach cancer confirmed by anatomo-pathological examination and who consulted in oncology and/or were hospitalized during the study period. Results: During the study period, 50 cases of gastric cancer were diagnosed, representing a hospital prevalence of 9.15%. The mean age of our patients was 57.6 years. The female gender was predominant (58% female). The most important risk factor was the consumption of salty foods (98%). Epigastric pain was the most frequent warning sign, found in 98% of patients, followed by vomiting (88%). Endoscopically, antral location was the most frequent with 58%. Adenocarcinoma was the most frequent histological appearance with 88%. The ulcerative-bourgeous aspect was the most frequent in 82% of patients. 66% of patients had secondary locations. The liver was the most frequent site of metastasis in 58% of patients. We found 66% of patients with stage IV pathology. In our study, 58% of patients received treatment, of which 83% of patients received palliative treatment. Surgical treatment was performed in 30%, partial gastrectomy in 80% of patients. In our study, 58% of patients received chemotherapy. The Folfox protocol was more used with 79.31%. At the end of our study, 32% of our patients were alive. The median survival was 2 months. Conclusion: Stomach cancer is not very common in our context. The implementation of awareness programs for the population is necessary.
Abstract: Introduction: According to WHO estimates, in 2020 there will be over 1.1 million cases of stomach cancer, including 770,000 deaths, and it remains the third leading cause of cancer deaths worldwide. In Burkina Faso, Zoungrana et al. (2021) noted that stomach cancer ranked second among digestive cancers, with a prevalence of 74.28%. The aim of our s...
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