Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma
American Journal of Internal Medicine
Volume 8, Issue 1, January 2020, Pages: 14-18
Received: Dec. 16, 2019; Accepted: Jan. 3, 2020; Published: Jan. 13, 2020
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Authors
Yurii Feshchenko, Department of Pulmonology, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Liudmyla Iashyna, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Svitlana Opimakh, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Maryna Polianska, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Viktoria Ignatieva, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Svitlana Moskalenko, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Galyna Gumenuk, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Inna Zvol, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Nataliia Vlasova, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
Liudmyla Halai, Department of Diagnostic, Therapy and Clinical Pharmacology of Lung Diseases, National Institute of Phthisiology and Pulmonology, Named After Feophil Gavrilovich Yanovskiy NAMS of Ukraine, Kiev, Ukraine
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Abstract
Background: Bronchial obstruction as characteristic feature of bronchial asthma (BA) can lead to gas exchange disorders. The distinction of asthma is that even in patients without clinical symptoms and almost normal spirometry parameters may have been significant gas exchange disorders including that due alveolar ventilation reducing. This study aimed to investigate lung ventilation pecularities in patients with BA. Results: Among patients with uncontrolled course of 40% have a smoking history with index (25,8 ± 8,8) pack-years. In patients with uncontrolled asthma "dead" space ventilation volume is (211 ± 8) ml, and part of the "dead" space of the tidal volume - (30,5 ± 1,5)%, which is statistically significantly greater than that rate for patients with controlled asthma - (176 ± 11) ml and (24,6 ± 0,5)%, respectively, p < 0.05. Alveolar ventilation in patients with uncontrolled disease course is lower, namely (7,3 ± 0,4) l/min. than when controlled asthma - (8,3 ± 0,2), p < 0.05. Conclusions: Lung ventilation parameters in patients with asthma without exacerbation in general slightly different from those in healthy subjects, but the effectiveness of alveolar ventilation is reduced by 14% in uncontrolled asthma due to high waste "dead" space ventilation.
Keywords
Bronchial Asthma, Lung Ventilation, Alveolar Ventilation
To cite this article
Yurii Feshchenko, Liudmyla Iashyna, Svitlana Opimakh, Maryna Polianska, Viktoria Ignatieva, Svitlana Moskalenko, Galyna Gumenuk, Inna Zvol, Nataliia Vlasova, Liudmyla Halai, Capnometry in the Assessment of Pulmonary Ventilation in Patients with Bronchial Asthma, American Journal of Internal Medicine. Special Issue: New Approaches to Manage Difficult-to-Control, Severe Asthma. Vol. 8, No. 1, 2020, pp. 14-18. doi: 10.11648/j.ajim.20200801.13
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Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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