| Peer-Reviewed

Clinical Profile of Child COVID-19 Patients of Bangladesh

Received: 29 December 2020    Accepted: 3 February 2021    Published: 10 February 2021
Views:       Downloads:
Abstract

Background: Millions of people worldwide have been affected by the COVID-19 pandemic. Due to the prevalence of malnutrition, refusal of immunization during a pandemic, nutritional anemia, air pollution, poverty, poor parental education, inadequate access to high-quality acute healthcare, the clinical characteristics and outcomes of children in Bangladesh may vary from other countries. Information on clinical presentations, outcomes, the relationship between disease incidence and the prevalence of associated disease in Bangladeshi children affected by COVID-19 are scarce. Objective: In this study, our main goal was to evaluate the clinical profile of pediatric COVID-19 patients in child corona unit of Dhaka Medical College Hospital, Bangladesh. Method: This single center observational study was conducted in Child Corona Unit of Dhaka Medical College Hospital (DMCH). A total of 1020 COVID-19 positive pediatric patients were included in this study. Results: In our study, 89.1% of patients had fever, 80.8% had a cough, 23.1% had diarrhea, and 70.8% had myalgia. According to CXR reports, 2.1% patients had ground-glass opacity, 38% had local patchy shadowing, 31.8% patients had bilateral patchy shadowing and 27.9% patients had interstitial abnormalities. Correlation of disease severity between without co-morbidity and with co-morbidity is statistically significant (p=0.01). Conclusion: This research revealed a variable range of presentations. This sheds light on the cases of COVID-19 in the pediatric population. Children with COVID-19 normally present with or are asymptomatic with different symptoms; infants may have a high risk of serious illness. However, most cases were reported in children 11-15 years of age and fever, cough, nasal congestion and dyspnoea were typical symptoms. Serious cases were those with co-morbidity and in order to save them additional attention during home care and prompt hospitalization therapy are needed.

Published in American Journal of Pediatrics (Volume 7, Issue 1)
DOI 10.11648/j.ajp.20210701.12
Page(s) 5-8
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

COVID-19 Pandemic, Clinical Profile, Pediatric Population

References
[1] Gorbalenya AE, Baker SC, Baric RS, de Groot RJ, Drosten C, Gulyaeva AA, et al. (March 2020). "The species, severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2". Nature Microbiology. 5 (4).
[2] "Coronavirus disease named Covid-19". BBC News Online. 11 February 2020. Archived from the original on 15 February 2020. Retrieved 15 February 2020.
[3] Surveillance case definitions for human infection with novel coronavirus (nCoV): interim guidance v1, January 2020 (Report). World Health Organization. January 2020. hdl: 10665/330376. WHO/2019-nCoV/Surveillance/v2020.1.
[4] Healthcare Professionals: Frequently Asked Questions and Answers". United States Centers for Disease Control and Prevention (CDC). 11 February 2020. Archived from the original on 14 February 2020. Retrieved 15 February 2020.
[5] Guan W, Ni Z., Hu Y, Liang W, Ou C, He J. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020; 382: 18 nejm.org.
[6] Lei H, Li Y, Xiao S, et al. Routes of transmission of influenza A H1N1, SARS CoV, and norovirus in air cabin: comparative analyses. Indoor Air 2018; 28: 394-403.
[7] Research (IEDCR), Institute of Epidemiology, Disease Control and. Research, corona.gov.bd (in Bengali). Retrieved 3 May 2020.
[8] Na Zhou et al: A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020 Feb 20.
[9] Bhandari, S., Bhargava, A., Sharma, S., Keshwani, P., Sharma, R., & Banerjee, S. (2020). Clinical profile of COVID-19 infected patients admitted in a tertiary care hospital in north India. J Assoc Physicians India, 68, 13-17.
[10] X. F. Lu, W. Gong, L. Wang, et al., Clinical features and high-resolution CT imaging findings of preliminary diagnosis novel coronavirus pneumonia, Zhonghuafangshexuezazhi 54 (00) (2020) E007, https://doi.org/10.3760/cma.j. ISSN. 1005-1201.2020.0007.
[11] Liu WJ, Zhao M, Liu K, Xu K, Wong G, Tan W, Gao GF. T-cell immunity of SARS-CoV: implications for vaccine development against MERS-CoV. Antiviral Res 2017; 137: 82–92.
[12] Huang C. Wang Y, Li X et al. Clinical features of patients infected with 2019 novel coronavirus in 312 Wuhan, China, Lancet 2020.
[13] Dong Y, Mo X, Hu Y, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020; 145: e2 0200702.
Cite This Article
  • APA Style

    Sayeeda Anwar, Iffat Ara Shamsad, AKM Amirul Morshed, Fatema Farzana. (2021). Clinical Profile of Child COVID-19 Patients of Bangladesh. American Journal of Pediatrics, 7(1), 5-8. https://doi.org/10.11648/j.ajp.20210701.12

    Copy | Download

    ACS Style

    Sayeeda Anwar; Iffat Ara Shamsad; AKM Amirul Morshed; Fatema Farzana. Clinical Profile of Child COVID-19 Patients of Bangladesh. Am. J. Pediatr. 2021, 7(1), 5-8. doi: 10.11648/j.ajp.20210701.12

    Copy | Download

    AMA Style

    Sayeeda Anwar, Iffat Ara Shamsad, AKM Amirul Morshed, Fatema Farzana. Clinical Profile of Child COVID-19 Patients of Bangladesh. Am J Pediatr. 2021;7(1):5-8. doi: 10.11648/j.ajp.20210701.12

    Copy | Download

  • @article{10.11648/j.ajp.20210701.12,
      author = {Sayeeda Anwar and Iffat Ara Shamsad and AKM Amirul Morshed and Fatema Farzana},
      title = {Clinical Profile of Child COVID-19 Patients of Bangladesh},
      journal = {American Journal of Pediatrics},
      volume = {7},
      number = {1},
      pages = {5-8},
      doi = {10.11648/j.ajp.20210701.12},
      url = {https://doi.org/10.11648/j.ajp.20210701.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20210701.12},
      abstract = {Background: Millions of people worldwide have been affected by the COVID-19 pandemic. Due to the prevalence of malnutrition, refusal of immunization during a pandemic, nutritional anemia, air pollution, poverty, poor parental education, inadequate access to high-quality acute healthcare, the clinical characteristics and outcomes of children in Bangladesh may vary from other countries. Information on clinical presentations, outcomes, the relationship between disease incidence and the prevalence of associated disease in Bangladeshi children affected by COVID-19 are scarce. Objective: In this study, our main goal was to evaluate the clinical profile of pediatric COVID-19 patients in child corona unit of Dhaka Medical College Hospital, Bangladesh. Method: This single center observational study was conducted in Child Corona Unit of Dhaka Medical College Hospital (DMCH). A total of 1020 COVID-19 positive pediatric patients were included in this study. Results: In our study, 89.1% of patients had fever, 80.8% had a cough, 23.1% had diarrhea, and 70.8% had myalgia. According to CXR reports, 2.1% patients had ground-glass opacity, 38% had local patchy shadowing, 31.8% patients had bilateral patchy shadowing and 27.9% patients had interstitial abnormalities. Correlation of disease severity between without co-morbidity and with co-morbidity is statistically significant (p=0.01). Conclusion: This research revealed a variable range of presentations. This sheds light on the cases of COVID-19 in the pediatric population. Children with COVID-19 normally present with or are asymptomatic with different symptoms; infants may have a high risk of serious illness. However, most cases were reported in children 11-15 years of age and fever, cough, nasal congestion and dyspnoea were typical symptoms. Serious cases were those with co-morbidity and in order to save them additional attention during home care and prompt hospitalization therapy are needed.},
     year = {2021}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Clinical Profile of Child COVID-19 Patients of Bangladesh
    AU  - Sayeeda Anwar
    AU  - Iffat Ara Shamsad
    AU  - AKM Amirul Morshed
    AU  - Fatema Farzana
    Y1  - 2021/02/10
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ajp.20210701.12
    DO  - 10.11648/j.ajp.20210701.12
    T2  - American Journal of Pediatrics
    JF  - American Journal of Pediatrics
    JO  - American Journal of Pediatrics
    SP  - 5
    EP  - 8
    PB  - Science Publishing Group
    SN  - 2472-0909
    UR  - https://doi.org/10.11648/j.ajp.20210701.12
    AB  - Background: Millions of people worldwide have been affected by the COVID-19 pandemic. Due to the prevalence of malnutrition, refusal of immunization during a pandemic, nutritional anemia, air pollution, poverty, poor parental education, inadequate access to high-quality acute healthcare, the clinical characteristics and outcomes of children in Bangladesh may vary from other countries. Information on clinical presentations, outcomes, the relationship between disease incidence and the prevalence of associated disease in Bangladeshi children affected by COVID-19 are scarce. Objective: In this study, our main goal was to evaluate the clinical profile of pediatric COVID-19 patients in child corona unit of Dhaka Medical College Hospital, Bangladesh. Method: This single center observational study was conducted in Child Corona Unit of Dhaka Medical College Hospital (DMCH). A total of 1020 COVID-19 positive pediatric patients were included in this study. Results: In our study, 89.1% of patients had fever, 80.8% had a cough, 23.1% had diarrhea, and 70.8% had myalgia. According to CXR reports, 2.1% patients had ground-glass opacity, 38% had local patchy shadowing, 31.8% patients had bilateral patchy shadowing and 27.9% patients had interstitial abnormalities. Correlation of disease severity between without co-morbidity and with co-morbidity is statistically significant (p=0.01). Conclusion: This research revealed a variable range of presentations. This sheds light on the cases of COVID-19 in the pediatric population. Children with COVID-19 normally present with or are asymptomatic with different symptoms; infants may have a high risk of serious illness. However, most cases were reported in children 11-15 years of age and fever, cough, nasal congestion and dyspnoea were typical symptoms. Serious cases were those with co-morbidity and in order to save them additional attention during home care and prompt hospitalization therapy are needed.
    VL  - 7
    IS  - 1
    ER  - 

    Copy | Download

Author Information
  • Department of Paediatrics, Dhaka Medical College Hospital, Dhaka, Bangladesh

  • Department of Paediatrics, Dhaka Medical College Hospital, Dhaka, Bangladesh

  • Department of Paediatric Hematology and Oncology, Dhaka Medical College Hospital, Dhaka, Bangladesh

  • Department of Paediatrics, Dhaka Medical College Hospital, Dhaka, Bangladesh

  • Sections