Small ruminants are an important lever for livestock production in Burkina Faso. With a numerically important livestock population, small ruminants contribute to the fight against poverty and participate greatly in the country's economy. Despite its importance, the development of small ruminant breeding is strongly hindered by parasitic diseases due to gastrointestinal nematodes. The appearance of parasite resistance to anthelmintic molecules makes the treatment of gastrointestinal parasitosis more and more problematic. In order to provide rural farmers with an effective and accessible biological alternative, C. sesamoïdes whole plant powder in vivo anthelmintic efficacy was tested on mossi sheep artificially infested. Mossi sheep was artificially infested with 3200 L3 larvae of H. contortus 30 days before the beginning of the experiment. Two (2) treated batches of 6 sheep each received respectively 14g/kg of body weight and 7g/kg of body weight while one negative control batch of 6 sheep without treatment and one positive batch of 6 sheep treated with levamisole were constituted during the 21 days of experimentation. The Fecal Eggs Count (FEC) reduction rate was high during treatment and reached 87.08% and 74.91% at D21 respectively for the dose of 14g/kg body weight and 7g/kg body weight. Statistical analysis revealed no significant difference between the two doses tested and between the two doses and the positive control, whereas the difference was significant (P<0.05) compared to the negative control. The animal’ weight evolution was not significant (P>0.05) compared to the negative control. The mean hematocrit level varied between D0 (27.66) and D21 (30.5) for the 14g/kg body weight dose while that of the animals treated with the 7g/kg body weight dose decreased slightly between D0 (27.33) and D21 (26.66). Biochemical blood tests show no suspicion of hepatic and renal impairment. Thus, C. sesamoïdes could be used as an alternative for the treatment of small ruminant’s gastrointestinal nematodes in the form of whole plant powder in Burkina Faso.
Published in | International Journal of Applied Agricultural Sciences (Volume 8, Issue 2) |
DOI | 10.11648/j.ijaas.20220802.11 |
Page(s) | 64-71 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Bioactive Forages, Anthelmintic, H. contortus, C. sesamoides
[1] | Akouedegni C. G., Daga F. D., Olounlade P. A., Allowanou G. O., Ahoussi E., H. TAMBOURA H. H., Hounzangbe-Adote M. S., 2019: Evaluation in vitro et in vivo des propriétés anthelminthiques de feuilles de Spondias mombin sur Haemonchus contortus des ovins djallonke. [In vitro and in vivo evaluation of anthelmintic properties of Spondias mombin leaves on Haemonchus contortus in djallonke sheep] Agronomie Africaine 31 (2): 213–222. |
[2] | Apala A. G. A., KOMOIN-OKA. A. M. A. C., Assare, K. R., Amian G., N’Goran, K. E, 2020: Efficacité des anthelminthiques usuels contre les strongles digestifs chez les ovins au centre de la Côte d’ivoire. [Efficacy of usual anthelmintic against digestive strongyles in sheep in the Ivory Coast center]. Int. J. Biol. Chem. Sci. 14 (2): 378-389. |
[3] | Awohouedji D. Y. G., 2014: Evaluation de l’utilisation de Khaya senegalensis et Boerhavia diffusa comme des alicaments dans la production ovine au Bénin. [Evaluation of Khaya senegalensis and Boerhavia diffusa use as alicaments in sheep production in Benin]. Thèse de Doctorat unique, Université D’Abomey Calavi. 154p. |
[4] | Bedigian D., 2019: Feeding the Forgotten: Wild and Cultivated Ceratotheca and Sesamum (Pedaliaceae) That Nourish and Provide Remedies in Africa. Economic Botany pp. 1-47. by The New York Botanical Garden Press, Bronx, NY 10458-5126 U.S.A. |
[5] | Belem A. M. G, Nikiema Z. N., Sawadogo L., Dorchies Ph., 2000: Parasites gastro-intestinaux des moutons et risques d’infestation parasitaire des pâturages en saison pluvieuse dans la région centrale du Burkina Faso. [Gastrointestinal parasites of sheep and risks of parasitic infestation of pastures during the rainy season in the central region of Burkina Faso] Révue Méd. Vét., 151, 5, 437-442. |
[6] | Brunet S., 2008: Analyse des mécanismes d’action antiparasitaire de plantes riches en substances polyphénoliques sur les nématodes du tube digestifs des ruminants.[Analysis of the antiparasitic action mechanisms of plants rich in polyphenolic substances on nematodes of the ruminant digestive tract] Thèse en Pathologie et nutrition, Université de Toulouse. 246p. |
[7] | Burke J. M., Kaplan R. M. B., Miller J. E., Terrill T. H., Getz W. R., S. Mobini S., Valencia E., M. J. Williams M. J., Williamson L. H., Vatta A. F., 2007: Accuracy of the FAMACHA system for on-farm use by sheep and goat producers in the southeastern United States. Veterinary Parasitology 147: 89–95. |
[8] | Dassou H. G., Ogni C. A., Yedomonhan H., Adomou A. C., Tossou M., J. T. Dougnon J. T., Akoegninou A., 2014: Diversité, usages vétérinaires et vulnérabilité des plantes médicinales au Nord-Bénin. [Diversity, veterinary uses and vulnerability of medicinal plants in North Benin]. Int. J. Biol. Chem. Sci. 8 (1): 189-210. |
[9] | Deghnouche K., Tlidjane M., Meziane T. et Touabti A., 2011 ! Influence du stade physiologique sur divers paramètres biochimiques sanguins chez la brebis Ouled Djellal des zones arides du Sud-Est algérien. [Influence of the physiological stage on various biochemical blood parameters in Ouled Djellal ewes from the arid zones of southeast Algeria] Revue Méd. Vét., 162 (1): 3-7. |
[10] | Dicko A., Konate A., Tindano B., Tapsoba A. S. R., Sanou M., Kabore A., Traore A., Bayala B., H. Tamboura H. H.,: In Vivo Anthelmintic Activity of Whole Plant Powder of Striga Hermonthica (Deli.) Benth. International Journal of Medical Science and Clinical Research Studies, 2022, 02 (01): 1-7. |
[11] | Djiérro K., 2002: Contribution à la connaissance de quelques plantes médicinales utilisées par les tradipraticiens pour la prise en charge des personnes vivant avec le VIH/SIDA dans la ville de Ouagadougou. [Contribution to the knowledge of some medicinal plants used by traditional practitioners for the care of people living with HIV/AIDS in the city of Ouagadougou] Doctorat en Pharmacie, Unité de Formation et de Recherches en Sciences de la Santé, Université de Ouagadougou. 113p. |
[12] | Dubreuil. P, Arsenault. J, Belanger. D, 2005: biochemical reference ranges for groups of ewes of different ages. VET REC; 156 (20); 636-8. |
[13] | Eichstadt, M., 2017: Evaluation de la résistance des strongles gastro-intestinaux aux anthelminthiques dans quatre élevages ovins allaitants de Corrèze. [Evaluation of gastrointestinal strongyles’s resistance to anthelmintics in four suckling sheep farms in Corrèze.]. Thèse de doctorat vétérinaire, Ecole Nationale Vétérinaire, Université de Toulouse. 163p. |
[14] | Githioria J. B., glundb J. H., Wallerb P. J., Baker R. L., 2002: Anthelmintic activity of preparations derived from Myrsine africanaandRapanea melanophloeosagainst the nematode parasite, Haemonchus contortus, of sheep. Journal of Ethnopharmacology 80: 187-191. |
[15] | Gnanda I. B., 2008: Importance socio-économique de la chèvre du sahel burkinabé et amélioration de sa productivité par l’alimentation. [Socio-economic importance of the Burkinabe Sahel goat and improvement of its productivity through feeding]. Thèse de Doctorat unique en développement rural, Université Polytechnique de Bobo-Dioulasso. 210p. |
[16] | Hoste H., LE Frileux Y., Pommaret, A., Gruner L., Van Quackebeke E., KOCH C., 1999: Importance du parasitisme par des strongles gastro-intestinaux chez les chèvres laitières dans le Sud-Est de la France. [Importance of parasitism by gastrointestinal strongyles in dairy goats in South-East France]. INRA Prod. Anim., 12 (5), 377-389. |
[17] | Iqbal Z., Lateef M., Jabbar A., Ghulam M., Nisar Khana M., 2005: Anthelmintic activity of Calotropis procera (Ait.) Ait. F. flowers in sheep. Journal of Ethnopharmacology 102: 256–261. |
[18] | Kabore A., 2009: Activités anthelminthiques de deux plantes tropicales testées in vivo et in vitro sur les strongles gastro-intestinaux des ovins de races mossis du Burkina Faso.[Anthelmintic activities of two tropical plants tested in vivo and in vitro on gastrointestinal strongyles in sheep of the Mossi breed in Burkina Faso]. Thèse de doctorat unique en développement rural, Université polytechnique de Bobo-Dioulasso. 167p. |
[19] | Kabore A., Belem A. M. G., Tamboura H. H., Traore A., Sawadogo L., 2009: In vitro anthelmintic effect of two medicinal plants (Anogeissus leiocarpus and Daniellia oliveri) on Haemonchus contortus, an abosomal nematode of sheep in Burkina Faso. African Journal of Biotechnology Vol. 8 (18): 4690-4695. |
[20] | Kanazoe, P. -O. O., Zabré G., Kaboré A., Konaté A., Traoré A., Tamboura H. H., Belem A. M. G., Millogo J., Legma B., 2017: Effets de supplémentation des feuilles séchées de Calotropis procera (WILLD) R. Br. sur les performances de croissance et la charge parasitaire des ovins en saison pluvieuse au Burkina Faso. [Effects of supplementation of dried leaves of Calotropis procera (WILLD) R. Br. on growth performance and parasite load of sheep during the rainy season in Burkina Faso] Int. J. Biol. Chem. Sci. 11 (5): 2028-2039. |
[21] | Kaneko. JJ, Harvey. J w, Bruss. ML, 2008: Clinical biochemistry of domestic animals. 6th. Edition. Elsevier. 896p. |
[22] | Lacroux C., 2006: Régulation des populations de Nématodes gastro-intestinaux (Haemonchus contortus et Trichostrongylus colubriformis) dans deux races ovines, INRA 401 et Barbados Black Belly. [Regulation of gastrointestinal nematode populations (Haemonchus contortus and Trichostrongylus colubriformis) in two sheep breeds, INRA 401 and Barbados Black Belly]. Thèse de doctorat, Institut National Polytechnique de Toulouse. 234p. |
[23] | Mendonça-Lima, F. W., SANTOS, R. B. D.; Santos, L. C., Zacharias, F., David, J. M., David, J. P., López, J. A., 2016: Anthelmintic activity of Cratyliamollis leaves against gastrointestinal nematodes in goats. Rev. Bras. Saúde Prod. Anim., Salvador, 17 (4): 753-762. |
[24] | Minaflinou sacca Sidi I. Y., Azando E. V. B., Olounlade, P. A., Hounzangbe-Adote, M. S., 2015: Effets combinés des feuilles de Newbouldia laevis et de Zanthoxylum zanthoxyloïdes sur les nématodes parasites gastro-intestinaux des ovins Djallonké. [Combined effects of Newbouldia laevis and Zanthoxylum zanthoxyloid leaves on gastrointestinal parasitic nematodes of djallonke sheep]. Int. J. Biol. Chem. Sci. 9 (4): 2078-2090. |
[25] | Ministère des ressources animales (MRA), 2019: Annuaire des statistiques d’élevage 2018. [Breeding statistics directory 2018]. 140p. |
[26] | Ndoutamia G. et Ganda K., 2005: Détermination des paramètres hématologiques et biochimiques des petits ruminants du Tchad. [Determination of hematological and biochemical parameters of small ruminants in Chad] Revue. Méd. Vét., 156 (4): 202-206. |
[27] | Ngambia Funkeu R., Pandey V. S., Dorny P., Killanga S., 2000: Etude épidémiologique des nématodes gastro-intestinaux chez les ovins en milieux urbain et périurbain à Maroua, Extrême Nord du Cameroun. [Epidemiological study of gastrointestinal nematodes in urban and peri-urban’s sheep areas of Maroua, Far North of Cameroon]. Revue Élev. Méd. vét. Pays trop., 53 (1): 17-22. |
[28] | Ogni C. A., Kpodekon M. T., Dassou H. G., Boko C. K., Koutinhouin B. G., Dougnon J. T., Youssao A. K. I., Yedomonha N. H., Akoegninou A., 2014: Inventaire ethno-pharmacologique des plantes utilisées dans le traitement des pathologies parasitaires dans les élevages extensifs et semi-intensifs du Bénin. [Ethno-pharmacological inventory of plants used in the treatment of parasitic pathologies in extensive and semi-intensive livestock in Benin]. Int. J. Biol. Chem. Sci. 8 (3): 1089-1102. |
[29] | Okombe V. E., 2011: Activité antihelminthique de la poudre d’écorce de racine de Vitex thomasii De Wild (Verbenaceae) sur Haemonchus contortus chez la chèvre. [Antihelmintic activity of Vitex thomasii De Wild (Verbenaceae) root bark powder on Haemonchus contortus in goats]. Doctorat de médecine vétérinaire et santé animale. Université de Lubumbashi. 258p. |
[30] | Olounladé A. P., Attakpa Y. E., Azando E. V. B., Hounzangbé – Adoté M., Hoste H., 2017: Effet In Vivo De Newbouldia laevis (Bignoniaceae) sur des Strongles Gastro-Intestinaux des Moutons. [In Vivo effect of Newbouldia laevis (Bignoniaceae) On sheep’s Gastro-Intestinal Strongyles] European Scientific Journal, 13 (12): 335-351. |
[31] | Ramos. J. J, Verde. M. T, Marca. M. C, Fernandez. A., 1994: Clinical chemical values and Variations in Rasa Aragonesa ewes and lambs. Small Ruminant Research Volume 13 (2): 133-139. |
[32] | Rogia Osman E. A., 2010: In vivo and in vitro Anthelmintic Activity of Balanites aegyptiaca and Artemisia herba Alba on Haemonchus contortus of sheep. Doctor of Philosophy degree, Faculty of Veterinary Science, University of Khartoum. 181p. |
[33] | Saccareau M., 2016: Modélisation épidémiologique et génétique des parasites gastro-intestinaux au sein d’un troupeau d’ovins. [Epidemiological and genetic modeling of gastrointestinal parasites in a sheep flock] Thèse de doctorat, Université de Toulouse. 228p. |
[34] | Somda N. R., Ilboudo D., 2018: pastoralisme et enjeux sanitaires. [pastoralism and health issues]. Bulletin PANORAMA 2018-2. 5p. |
[35] | Torres A. J. F. J., Hoste H., 2008: Alternative or improved methods to limits gastro-intestinal parasitism in grazing sheeps and goats. Smalls Ruminants Research 77: 159-173. |
[36] | Yakubu M. T., Opakunle F. K., Salimon S. S., Ajiboye T. O., Bamisaye F. A., Quadri A. L., 2012: Antidiarrheal activity of aqueous leaf extract of Ceratotheca sesamoides in rats. Bangladesh J Pharmacol, 7: 14-20. |
APA Style
Amadou Dicko, Almamy Konate, Genevieve Zabre, Arnaud Stephane Rayangnewende Tapsoba, Basile Tindano, et al. (2022). In Vivo Anthelminthic Activity of Ceratotheca sesamoïdes Endl Whole Plant Powder. International Journal of Applied Agricultural Sciences, 8(2), 64-71. https://doi.org/10.11648/j.ijaas.20220802.11
ACS Style
Amadou Dicko; Almamy Konate; Genevieve Zabre; Arnaud Stephane Rayangnewende Tapsoba; Basile Tindano, et al. In Vivo Anthelminthic Activity of Ceratotheca sesamoïdes Endl Whole Plant Powder. Int. J. Appl. Agric. Sci. 2022, 8(2), 64-71. doi: 10.11648/j.ijaas.20220802.11
AMA Style
Amadou Dicko, Almamy Konate, Genevieve Zabre, Arnaud Stephane Rayangnewende Tapsoba, Basile Tindano, et al. In Vivo Anthelminthic Activity of Ceratotheca sesamoïdes Endl Whole Plant Powder. Int J Appl Agric Sci. 2022;8(2):64-71. doi: 10.11648/j.ijaas.20220802.11
@article{10.11648/j.ijaas.20220802.11, author = {Amadou Dicko and Almamy Konate and Genevieve Zabre and Arnaud Stephane Rayangnewende Tapsoba and Basile Tindano and Moumouni Sanou and Adama Kabore and Amadou Traore and Bale Bayala and Hamidou Hamadou Tamboura}, title = {In Vivo Anthelminthic Activity of Ceratotheca sesamoïdes Endl Whole Plant Powder}, journal = {International Journal of Applied Agricultural Sciences}, volume = {8}, number = {2}, pages = {64-71}, doi = {10.11648/j.ijaas.20220802.11}, url = {https://doi.org/10.11648/j.ijaas.20220802.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijaas.20220802.11}, abstract = {Small ruminants are an important lever for livestock production in Burkina Faso. With a numerically important livestock population, small ruminants contribute to the fight against poverty and participate greatly in the country's economy. Despite its importance, the development of small ruminant breeding is strongly hindered by parasitic diseases due to gastrointestinal nematodes. The appearance of parasite resistance to anthelmintic molecules makes the treatment of gastrointestinal parasitosis more and more problematic. In order to provide rural farmers with an effective and accessible biological alternative, C. sesamoïdes whole plant powder in vivo anthelmintic efficacy was tested on mossi sheep artificially infested. Mossi sheep was artificially infested with 3200 L3 larvae of H. contortus 30 days before the beginning of the experiment. Two (2) treated batches of 6 sheep each received respectively 14g/kg of body weight and 7g/kg of body weight while one negative control batch of 6 sheep without treatment and one positive batch of 6 sheep treated with levamisole were constituted during the 21 days of experimentation. The Fecal Eggs Count (FEC) reduction rate was high during treatment and reached 87.08% and 74.91% at D21 respectively for the dose of 14g/kg body weight and 7g/kg body weight. Statistical analysis revealed no significant difference between the two doses tested and between the two doses and the positive control, whereas the difference was significant (P0.05) compared to the negative control. The mean hematocrit level varied between D0 (27.66) and D21 (30.5) for the 14g/kg body weight dose while that of the animals treated with the 7g/kg body weight dose decreased slightly between D0 (27.33) and D21 (26.66). Biochemical blood tests show no suspicion of hepatic and renal impairment. Thus, C. sesamoïdes could be used as an alternative for the treatment of small ruminant’s gastrointestinal nematodes in the form of whole plant powder in Burkina Faso.}, year = {2022} }
TY - JOUR T1 - In Vivo Anthelminthic Activity of Ceratotheca sesamoïdes Endl Whole Plant Powder AU - Amadou Dicko AU - Almamy Konate AU - Genevieve Zabre AU - Arnaud Stephane Rayangnewende Tapsoba AU - Basile Tindano AU - Moumouni Sanou AU - Adama Kabore AU - Amadou Traore AU - Bale Bayala AU - Hamidou Hamadou Tamboura Y1 - 2022/03/15 PY - 2022 N1 - https://doi.org/10.11648/j.ijaas.20220802.11 DO - 10.11648/j.ijaas.20220802.11 T2 - International Journal of Applied Agricultural Sciences JF - International Journal of Applied Agricultural Sciences JO - International Journal of Applied Agricultural Sciences SP - 64 EP - 71 PB - Science Publishing Group SN - 2469-7885 UR - https://doi.org/10.11648/j.ijaas.20220802.11 AB - Small ruminants are an important lever for livestock production in Burkina Faso. With a numerically important livestock population, small ruminants contribute to the fight against poverty and participate greatly in the country's economy. Despite its importance, the development of small ruminant breeding is strongly hindered by parasitic diseases due to gastrointestinal nematodes. The appearance of parasite resistance to anthelmintic molecules makes the treatment of gastrointestinal parasitosis more and more problematic. In order to provide rural farmers with an effective and accessible biological alternative, C. sesamoïdes whole plant powder in vivo anthelmintic efficacy was tested on mossi sheep artificially infested. Mossi sheep was artificially infested with 3200 L3 larvae of H. contortus 30 days before the beginning of the experiment. Two (2) treated batches of 6 sheep each received respectively 14g/kg of body weight and 7g/kg of body weight while one negative control batch of 6 sheep without treatment and one positive batch of 6 sheep treated with levamisole were constituted during the 21 days of experimentation. The Fecal Eggs Count (FEC) reduction rate was high during treatment and reached 87.08% and 74.91% at D21 respectively for the dose of 14g/kg body weight and 7g/kg body weight. Statistical analysis revealed no significant difference between the two doses tested and between the two doses and the positive control, whereas the difference was significant (P0.05) compared to the negative control. The mean hematocrit level varied between D0 (27.66) and D21 (30.5) for the 14g/kg body weight dose while that of the animals treated with the 7g/kg body weight dose decreased slightly between D0 (27.33) and D21 (26.66). Biochemical blood tests show no suspicion of hepatic and renal impairment. Thus, C. sesamoïdes could be used as an alternative for the treatment of small ruminant’s gastrointestinal nematodes in the form of whole plant powder in Burkina Faso. VL - 8 IS - 2 ER -