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Factors of Non-adherence to Antidiabetic Drugs in Type 2 Diabetics, Antananarivo Madagascar

Received: 14 August 2021     Accepted: 6 September 2021     Published: 12 October 2021
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Abstract

Introduction: The non-adherence to therapy of diabetics is grafted with heavy morbidity and mortality. Our study aims to determine the factors of non-adherence with antidiabetic drugs in type 2 diabetics. Methods: This was a descriptive and analytical cross-sectional study, carried out in the Endocrinology Unit of the Joseph Raseta University Hospital Center. Befelatanana, Antananarivo, over a period of 7 months. Adherence to treatment was assessed by the Morisky scale. Results: We retained 104 patients with an average age of 58.36 years, consisting of 52.88% of women. Adherence was high, medium, and low in 6.73%, 31.73% and 61.54% of cases, respectively. From their attending physician, explanations of the diabetic disease and their treatment were received by 90.38% and 66.35% of patients, respectively. However, these patients were aware of their disease and treatment in 18.27% and 41.35% of cases, respectively. The most observed non-adherence factors were the absence of an appointment given by the physician (30.77%), the feeling of well-being (24.04%), the lack of money (21.15%), forgetting (20.19%) and advice from a traditional practitioner (16.35%). Only the doctor's explanation for diabetes treatment was significantly associated with medication nonadherence (p=0.0310). Conclusion: Continuing medical education for physician is essential so that they can strengthen therapeutic education and follow-up for their diabetics.

Published in International Journal of Diabetes and Endocrinology (Volume 6, Issue 4)
DOI 10.11648/j.ijde.20210604.11
Page(s) 125-130
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Antidiabetic Drugs, Diabetes Mellitus, Madagascar, Morisky Score, Non-adherence

References
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Cite This Article
  • APA Style

    Sitraka Angelo Raharinavalona, Rija Eric Raherison, Thierry Razanamparany, Solofo Andrianarivelo Ralamboson, Andrinirina Dave Patrick Rakotomalala, et al. (2021). Factors of Non-adherence to Antidiabetic Drugs in Type 2 Diabetics, Antananarivo Madagascar. International Journal of Diabetes and Endocrinology, 6(4), 125-130. https://doi.org/10.11648/j.ijde.20210604.11

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    ACS Style

    Sitraka Angelo Raharinavalona; Rija Eric Raherison; Thierry Razanamparany; Solofo Andrianarivelo Ralamboson; Andrinirina Dave Patrick Rakotomalala, et al. Factors of Non-adherence to Antidiabetic Drugs in Type 2 Diabetics, Antananarivo Madagascar. Int. J. Diabetes Endocrinol. 2021, 6(4), 125-130. doi: 10.11648/j.ijde.20210604.11

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    AMA Style

    Sitraka Angelo Raharinavalona, Rija Eric Raherison, Thierry Razanamparany, Solofo Andrianarivelo Ralamboson, Andrinirina Dave Patrick Rakotomalala, et al. Factors of Non-adherence to Antidiabetic Drugs in Type 2 Diabetics, Antananarivo Madagascar. Int J Diabetes Endocrinol. 2021;6(4):125-130. doi: 10.11648/j.ijde.20210604.11

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  • @article{10.11648/j.ijde.20210604.11,
      author = {Sitraka Angelo Raharinavalona and Rija Eric Raherison and Thierry Razanamparany and Solofo Andrianarivelo Ralamboson and Andrinirina Dave Patrick Rakotomalala and Hanta Marie Danielle Vololontiana and Radonirina Lazasoa Andrianasolo},
      title = {Factors of Non-adherence to Antidiabetic Drugs in Type 2 Diabetics, Antananarivo Madagascar},
      journal = {International Journal of Diabetes and Endocrinology},
      volume = {6},
      number = {4},
      pages = {125-130},
      doi = {10.11648/j.ijde.20210604.11},
      url = {https://doi.org/10.11648/j.ijde.20210604.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20210604.11},
      abstract = {Introduction: The non-adherence to therapy of diabetics is grafted with heavy morbidity and mortality. Our study aims to determine the factors of non-adherence with antidiabetic drugs in type 2 diabetics. Methods: This was a descriptive and analytical cross-sectional study, carried out in the Endocrinology Unit of the Joseph Raseta University Hospital Center. Befelatanana, Antananarivo, over a period of 7 months. Adherence to treatment was assessed by the Morisky scale. Results: We retained 104 patients with an average age of 58.36 years, consisting of 52.88% of women. Adherence was high, medium, and low in 6.73%, 31.73% and 61.54% of cases, respectively. From their attending physician, explanations of the diabetic disease and their treatment were received by 90.38% and 66.35% of patients, respectively. However, these patients were aware of their disease and treatment in 18.27% and 41.35% of cases, respectively. The most observed non-adherence factors were the absence of an appointment given by the physician (30.77%), the feeling of well-being (24.04%), the lack of money (21.15%), forgetting (20.19%) and advice from a traditional practitioner (16.35%). Only the doctor's explanation for diabetes treatment was significantly associated with medication nonadherence (p=0.0310). Conclusion: Continuing medical education for physician is essential so that they can strengthen therapeutic education and follow-up for their diabetics.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Factors of Non-adherence to Antidiabetic Drugs in Type 2 Diabetics, Antananarivo Madagascar
    AU  - Sitraka Angelo Raharinavalona
    AU  - Rija Eric Raherison
    AU  - Thierry Razanamparany
    AU  - Solofo Andrianarivelo Ralamboson
    AU  - Andrinirina Dave Patrick Rakotomalala
    AU  - Hanta Marie Danielle Vololontiana
    AU  - Radonirina Lazasoa Andrianasolo
    Y1  - 2021/10/12
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ijde.20210604.11
    DO  - 10.11648/j.ijde.20210604.11
    T2  - International Journal of Diabetes and Endocrinology
    JF  - International Journal of Diabetes and Endocrinology
    JO  - International Journal of Diabetes and Endocrinology
    SP  - 125
    EP  - 130
    PB  - Science Publishing Group
    SN  - 2640-1371
    UR  - https://doi.org/10.11648/j.ijde.20210604.11
    AB  - Introduction: The non-adherence to therapy of diabetics is grafted with heavy morbidity and mortality. Our study aims to determine the factors of non-adherence with antidiabetic drugs in type 2 diabetics. Methods: This was a descriptive and analytical cross-sectional study, carried out in the Endocrinology Unit of the Joseph Raseta University Hospital Center. Befelatanana, Antananarivo, over a period of 7 months. Adherence to treatment was assessed by the Morisky scale. Results: We retained 104 patients with an average age of 58.36 years, consisting of 52.88% of women. Adherence was high, medium, and low in 6.73%, 31.73% and 61.54% of cases, respectively. From their attending physician, explanations of the diabetic disease and their treatment were received by 90.38% and 66.35% of patients, respectively. However, these patients were aware of their disease and treatment in 18.27% and 41.35% of cases, respectively. The most observed non-adherence factors were the absence of an appointment given by the physician (30.77%), the feeling of well-being (24.04%), the lack of money (21.15%), forgetting (20.19%) and advice from a traditional practitioner (16.35%). Only the doctor's explanation for diabetes treatment was significantly associated with medication nonadherence (p=0.0310). Conclusion: Continuing medical education for physician is essential so that they can strengthen therapeutic education and follow-up for their diabetics.
    VL  - 6
    IS  - 4
    ER  - 

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Author Information
  • Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar

  • Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar

  • Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar

  • Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar

  • Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar

  • Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar

  • Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar

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