Introduction: Diabetes mellitus is a chronic pathology related to chronic hyperglycemia. Its seriousness is based on its complications, which are often a source of hospitalization and death. Our aim was to identify both the main causes of hospitalization and death in Malagasy diabetic patients. Methods: We conducted a descriptive and analytical cross-sectional study including all diabetic patients hospitalized between January and June 2020 at the unit of Endocrinology at the Joseph Raseta Befelatanana hospital, Antananarivo. Results: The mean age of our patients was 56.66 ± 13.03 years, the sex ratio was 0.82. Diabetes mellitus were known before admissions to hospital in 81.95% cases. Type 2 diabetes mellitus was found in the majority of our patients. The mainly causes of hospitalization were cardiovascular, in particular stroke, nephropathy and heart failure. The second cause of hospitalization was infections with a predilection on the pulmonary tract. The causes of hospital mortality were also cardiovascular, dominated by heart failure. Heart failure was a significant factor influencing mortality in these diabetic patients (OR = 4.65; 95% IC = 1.80 – 11.85; p < 0.01). Conclusion: To know the causes of morbi-mortality in diabetic patients may guide from the initiation of the preventions to the most precise multidisciplinary decisions. Prior investigations regarding diabetic patients with heart failure are needed. Thus, influences on the treatments, on follow-up and on subsequent researches may be appeared.
| Published in | International Journal of Diabetes and Endocrinology (Volume 7, Issue 3) |
| DOI | 10.11648/j.ijde.20220703.14 |
| Page(s) | 63-69 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Cardiovascular Diseases, Diabetes Mellitus, Heart Failure, Hospitalization, Mortality
| [1] | Ceriello A., Monnier L, Owens D. Glycaemic variability in diabetes: clinical and therapeutic implications. The Lancet Diabetes & Endocrinology. 2018: 1-10. |
| [2] | Pearson-Stuttard J, Cheng YJ, Bennett J, Vamos EP, Zhou B, Valabhji J et al. Trends in leading causes of hospitalisation of adults with diabetes in England from 2003 to 2018: an epidemiological analysis of linked primary care records. Lancet Diabetes Endocrinol. 2022; 10: 46-57. |
| [3] | International Diabetes Federation. Diabetes Atlas. 9th ed. Belgium: International Diabetes Federation, 2019. Accessed "http://www.idforg/diabetesatlas. |
| [4] | Sarfo-Kantanka O, Sarfo FS, Ansah EO, Eghan B, Ayisi-Boateng NK, Acheamfour-Akowuah E. Secular Trends in Admissions and Mortality Rates from Diabetes Mellitus in the Central Belt of Ghana: A 31-Year Review. PLoSONE. 2016: 11; 1-4. |
| [5] | Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projection for 2030. Diabetes Care. 27: 1047-53. |
| [6] | World Health Organization. Global Report on diabetes. 2016 http://who. int/ diabetes/ global- report/ en/ (accessed 07 April 2016). |
| [7] | American Diabetes Association. Diagnostics and classification of diabetes: Standards of Medical Care in Diabetes - 2021. Diabetes Care. 2021; 44 (Suppl. 1): S15-33. |
| [8] | Hertz JT, Sakita FM, Manavalan P, Madut DB, Thielman NM, Mmbaga BT, et al. The burden of hypertension and diabetes in an Emergency Department in Northern Tanzania. Ethnicity and Disease. 2019: 29 (4): 559-66. |
| [9] | Nichols GA, Joshua-Gotlib S, Parasuraman S. Glycemic Control and Risk of Cardiovascular Disease Hospitalization of All-cause Mortality. J Am CollCardiol. 2013; 62 (2): 121-7. |
| [10] | Yoo H, Choo E and Lee S. Study of hospitalization and mortality in Korean diabetic patients using the diabetes complications severity index. BMC Endocrine Disorders. 2020; 20 (122): 1-10. |
| [11] | Clarke PM, Glasziou P, Patel A, Chalmers J, Woodward M, Stephen B, et al, on behalf of the ADVANCE Collaborative Group. Event Rates, Hospital Utilization, and Costs Associated with Major Complications of Diabetes: A Multicountry Comparative Analysis. PLoSMedicine. 2010; 7 (2): 1-11. |
| [12] | Montaut A. Health and health care use by women and men: first results of the 2008 Handicap-Santé survey. 2010. |
| [13] | Robert E, Samb OM. For a map of free healthcare in West-Africa. Comtemp African Rev. 2012; 3: 100. |
| [14] | Romon I, Dupin J, Fosse S, Dalichampt M, Dray-Spira R, Varroud-Vial M, et al. Relationship between socioeconomic characteristics, health status, use of health care resources and quality of care in persons with diabetes, Entred 2001. Bull Épidémiologique Hebd. 2006; 45: 347-50. |
| [15] | Kefale AT, Tesfahun CE, Esayas KG. Hospitalization Pattern and Treatment Outcome and Diabetic Patients Admitted to a Teaching Hospital in Ethiopia: A Prospective Observational Study. Journal of Health, Medecine and Nursing. 2016; 28: 34-41. |
| [16] | Jaffiol C. The burden of diabetes in Africa: a major public health problem. Bull Acad Nattle Med. 2011; 195 (6): 1239-54. |
| [17] | Raherison RE, Ramilitiana B, Raharinavalona SA, Rakotomalala DP. Les nouveaux diabétiques observés à l’Hôpital Joseph Raseta Befelatanana d’Antananarivo (2002-2003). La Revue médicale de Madagascar 2015; 5 (1): 526-30. |
| [18] | Afaf MS, Al-Adsani, Kholouda AA. Reasons for hospitalizations in adults with diabetes in Kuwait. IJDM. 2015; 3; 65-9. |
| [19] | Raherison RE, Raharinavalona SA, Randriamboavonjy RL, Rakotoarivelo RA, Randria MJD, Rakotomalala ADP. Common infection in Malagasy hospitalized diabetics at the Joseph Raseta Befelatanana Hospital, Anatanarivo, Madagascar. Rev Med Madag. 2015. 5 (2): 577-81. |
| [20] | Bigdeli M, Jacobs B, Rithy Men C, Nilsen K, Damme WV, Dujardin B. Access to Treatment for Diabetes and Hypertension in Rural Cambodia: Performance of Existing Social Health Protection Schemes. Journal pone. 2017: 1-18. |
| [21] | Raharinavalona SA, Raherison RE, Razanamparany T, Ralamboson SA, Rakotomalala ADP, Vololontiana HMD, Andrianasolo RL. Factors of Non-adherence to Antidiabetic Drugs in Type 2 Diabetics, Antananarivo Madagascar. International Journal of Diabetes and Endocrinology. 2021; 6 (4): 125-30. |
| [22] | Khalid JM, Raluy-Callado M, Curtis BH, Boye KS, Maguire A, Reaney R. Rates and risk of hospitalisation among patients with type 2 diabetes: retrospective cohort study using the UK General Practice Research Database linked to English Hospital Episode Statistics. Int J Clin Pract. 2014; 68 (1): 40-8. |
| [23] | Blecker S, Park H, and Katz SD. Association of HbA1c with hospitalization and mortality among patients with heart failure and diabetes. BMC Cardiovascular Disorders. 2016; 16 (99): 1-8. |
| [24] | Raharinavalona SA, Raherison RE, Razanamparany T, RalambosonSA, Vololontiana HMD, Rakotomalala ADP. Insulin Availability and Affordability in the Urban Municipality of Antananarivo, Madagascar. International Journal of Diabetes and Endocrinology 2021; 6 (1): 1-4. |
| [25] | Chen H, Zhang Y, Wu D, Gong C, Pan Q, Dong X et al. Comorbidity in patient adults hospitalized with type 2 diabetes in Northeast China: an Analysis of Hospital discharge Data from 2002 to 2013. Bio Med reseach International. 2016: 1-9. |
| [26] | Nowakowska M, Zghebi SS, Ashcroft DM, Buchan I, Chew-Graham C, Holt T et al. The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort. BMC Medicine. 2019; 17 (145): 1-10. |
| [27] | Cosentino F, Grant PJ, Aboyans V, Bailey CJ, Ceriello A, Delgado V et al. ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. EHJ. 2020; 41: 255-323. |
| [28] | Karinja M, Pillai G, Schlienger R, Tanner M and Ogutu B. Care-Seeking Dynamics among Patients with Diabetes Mellitus and Hypertension in Selected Rural Settings in Kenya. Int J Environ Rev Public Health. 2019; 16: 1-15. |
| [29] | Tracking universal health coverage 2021 Global Monitoring Report. World Health Organization. The World Bank Group. Available at https://www.who.int/data/monitoring-universal-health-coverage. |
| [30] | Rosa R, Nita ME, Rached R, Donato B, Rahal E. Estimated hospitalizations attributable to Diabetes Mellitus within the public healthcare system in Brazil from 2008 to 2010: study DIAPS 79. Rev Assoc Med Bras. 2014; 60 (3): 222-230. |
| [31] | Tabbalat A, Dargham S, Suwaidi JAI, Aboulsoud S, Jerdi SAI, Khalil CA. Mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US: a recent analysis from the National Inpatient Sample. Scientific Reports. 2021; 11: 1-11. |
| [32] | Canto ED, Ceriello A, Lars Ryden L, Ferrini M, Hansen TB, Schnell O et al. Diabetes as a cardiovascular risk factor: An overview of Global trends of macro and micro vascular complications. European Journal of Preventive Cardiology. ESC. 2019; 0 (0): 1-8. |
| [33] | Tziakas DN, Chalikias GK, Kaski JC. Epidemiology of the diabetic heart. Coron Artery Dis. 2005, 16 (Suppl 1): S3-S10. |
| [34] | Perez-Belmonte LM, Lara-Rojas CM, Lopez-Carmona MD, Guijarro-Merino R, Bernal-Lopez MR, and Gomez-Huelgas R. National Trends in Heart Failure Hospitalization Rates in Patients With Diabetes Mellitus: 1997-2010. Rev EspCardiol. 2017; 32: 1-2. |
| [35] | Korbel L, Spencer JD. Diabetes mellitus and infection: an evaluation of hospital utilization and management costs in the United States. Journal of Diabetes and Its Complications. 2015: 29; 192-5. |
| [36] | Muller LMAJ, Gorter KJ, Hak E, Goodzwaard WL, Schellevis FG, Hoepelman AIM et al. Increase Risk of Common infections in patients with type 1 and type 2 Diabetes Mellitus. Clin Infect Dis. 2005; 41 (3): 281-8. |
| [37] | Zhong VW, Juhaeri J, Mayer-Davis E. J. Trends in Hospital Admission for Diabetic Ketoacidosis in Adults with Type 1 and Type 2 Diabetes in England, 1998-2013: A Retrospective Cohort Study. Diabetes Care. 2018; 41 (9): 1870-77. |
| [38] | Rafamantanantsoa JF, Rabenjarison F, Rakotobe AHLE, Raharinavalona SA, Razanadrasara J, Ralijaona O, Rakotomalala ADP, Rakotoarison RCN. Mortality related to diabetes at the Endocrinology unit of the Joseph Raseta Academic Medical Center, Befelatanana Antananarivo. Rev Anesth.-Reanim Med UrgToxicol. 2019; 11 (1): 34-8. |
| [39] | Celestin Monzele NN. Kensese J. The determinants of mortality in diabetic patients (case of the Kinshasa provincial general reference hospital and Saint Joseph hospital) from January 2009 to June 2012. Bulletin of the national center for the epidemiology of diabetes. April 2013. 4p. |
| [40] | Park J, Peters PA. Mortality from diabetes mellitus, 2004 to 2008: A multiple-cause-of-death analysis. Health reports. 2014: 25 (3); 12-6. |
| [41] | Tirfe M, Nedi T, Mekonnen D, Beyene Berha AB. Treatment outcome and its predictors among patients of acute heart failure at a tertiary care hospital in Ethiopia: a prospective observational study. BMC Cardiovascular Disorders. 2020; 20 (16): 1-10. |
| [42] | Bivigou EA, Allognon MC, Ndoume F, Jean Bruno, Mipinda JB, Nzengue EE. Mortality rate in patients with heart failure at the Libreville University Hospital and associated factors. Pamj. 2018; 31 (27): 1-8. |
APA Style
Tsikinirina Valisoa Randrianomanana, Thierry Razanamparany, Sitraka Angelo Raharinavalona, Rija Eric Raherison, Haritsiky Robertini Ramalanjaona, et al. (2022). Morbi - Mortality of Diabetic Patients Hospitalized at the Unit of Endocrinology at the Joseph Raseta Befelatanana Hospital, Antananarivo. International Journal of Diabetes and Endocrinology, 7(3), 63-69. https://doi.org/10.11648/j.ijde.20220703.14
ACS Style
Tsikinirina Valisoa Randrianomanana; Thierry Razanamparany; Sitraka Angelo Raharinavalona; Rija Eric Raherison; Haritsiky Robertini Ramalanjaona, et al. Morbi - Mortality of Diabetic Patients Hospitalized at the Unit of Endocrinology at the Joseph Raseta Befelatanana Hospital, Antananarivo. Int. J. Diabetes Endocrinol. 2022, 7(3), 63-69. doi: 10.11648/j.ijde.20220703.14
AMA Style
Tsikinirina Valisoa Randrianomanana, Thierry Razanamparany, Sitraka Angelo Raharinavalona, Rija Eric Raherison, Haritsiky Robertini Ramalanjaona, et al. Morbi - Mortality of Diabetic Patients Hospitalized at the Unit of Endocrinology at the Joseph Raseta Befelatanana Hospital, Antananarivo. Int J Diabetes Endocrinol. 2022;7(3):63-69. doi: 10.11648/j.ijde.20220703.14
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Download@article{10.11648/j.ijde.20220703.14,
author = {Tsikinirina Valisoa Randrianomanana and Thierry Razanamparany and Sitraka Angelo Raharinavalona and Rija Eric Raherison and Haritsiky Robertini Ramalanjaona and Miora Maeva Arielle Andrianiaina and Andrianirina Dave Patrick Rakotomalala},
title = {Morbi - Mortality of Diabetic Patients Hospitalized at the Unit of Endocrinology at the Joseph Raseta Befelatanana Hospital, Antananarivo},
journal = {International Journal of Diabetes and Endocrinology},
volume = {7},
number = {3},
pages = {63-69},
doi = {10.11648/j.ijde.20220703.14},
url = {https://doi.org/10.11648/j.ijde.20220703.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20220703.14},
abstract = {Introduction: Diabetes mellitus is a chronic pathology related to chronic hyperglycemia. Its seriousness is based on its complications, which are often a source of hospitalization and death. Our aim was to identify both the main causes of hospitalization and death in Malagasy diabetic patients. Methods: We conducted a descriptive and analytical cross-sectional study including all diabetic patients hospitalized between January and June 2020 at the unit of Endocrinology at the Joseph Raseta Befelatanana hospital, Antananarivo. Results: The mean age of our patients was 56.66 ± 13.03 years, the sex ratio was 0.82. Diabetes mellitus were known before admissions to hospital in 81.95% cases. Type 2 diabetes mellitus was found in the majority of our patients. The mainly causes of hospitalization were cardiovascular, in particular stroke, nephropathy and heart failure. The second cause of hospitalization was infections with a predilection on the pulmonary tract. The causes of hospital mortality were also cardiovascular, dominated by heart failure. Heart failure was a significant factor influencing mortality in these diabetic patients (OR = 4.65; 95% IC = 1.80 – 11.85; p < 0.01). Conclusion: To know the causes of morbi-mortality in diabetic patients may guide from the initiation of the preventions to the most precise multidisciplinary decisions. Prior investigations regarding diabetic patients with heart failure are needed. Thus, influences on the treatments, on follow-up and on subsequent researches may be appeared.},
year = {2022}
}
TY - JOUR T1 - Morbi - Mortality of Diabetic Patients Hospitalized at the Unit of Endocrinology at the Joseph Raseta Befelatanana Hospital, Antananarivo AU - Tsikinirina Valisoa Randrianomanana AU - Thierry Razanamparany AU - Sitraka Angelo Raharinavalona AU - Rija Eric Raherison AU - Haritsiky Robertini Ramalanjaona AU - Miora Maeva Arielle Andrianiaina AU - Andrianirina Dave Patrick Rakotomalala Y1 - 2022/08/24 PY - 2022 N1 - https://doi.org/10.11648/j.ijde.20220703.14 DO - 10.11648/j.ijde.20220703.14 T2 - International Journal of Diabetes and Endocrinology JF - International Journal of Diabetes and Endocrinology JO - International Journal of Diabetes and Endocrinology SP - 63 EP - 69 PB - Science Publishing Group SN - 2640-1371 UR - https://doi.org/10.11648/j.ijde.20220703.14 AB - Introduction: Diabetes mellitus is a chronic pathology related to chronic hyperglycemia. Its seriousness is based on its complications, which are often a source of hospitalization and death. Our aim was to identify both the main causes of hospitalization and death in Malagasy diabetic patients. Methods: We conducted a descriptive and analytical cross-sectional study including all diabetic patients hospitalized between January and June 2020 at the unit of Endocrinology at the Joseph Raseta Befelatanana hospital, Antananarivo. Results: The mean age of our patients was 56.66 ± 13.03 years, the sex ratio was 0.82. Diabetes mellitus were known before admissions to hospital in 81.95% cases. Type 2 diabetes mellitus was found in the majority of our patients. The mainly causes of hospitalization were cardiovascular, in particular stroke, nephropathy and heart failure. The second cause of hospitalization was infections with a predilection on the pulmonary tract. The causes of hospital mortality were also cardiovascular, dominated by heart failure. Heart failure was a significant factor influencing mortality in these diabetic patients (OR = 4.65; 95% IC = 1.80 – 11.85; p < 0.01). Conclusion: To know the causes of morbi-mortality in diabetic patients may guide from the initiation of the preventions to the most precise multidisciplinary decisions. Prior investigations regarding diabetic patients with heart failure are needed. Thus, influences on the treatments, on follow-up and on subsequent researches may be appeared. VL - 7 IS - 3 ER -
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