Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers

Eduardo Alfredo Duro; Elizabeth Marcela Rizzo

doi:doi:10.11648/j.ijidt.20170201.15

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Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers

Eduardo Alfredo Duro, Elizabeth Marcela Rizzo

Published in International Journal of Infectious Diseases and Therapy (Volume 2, Issue 1)

Received: 18 January 2017 Accepted: 6 February 2017 Published: 24 February 2017

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Abstract

The diagnosis of tuberculosis (TB) in a newborn is often difficult as clinical signs are nonspecific. Neonatal infection is rare but it has a mortality up to 50%. The suspicion of TB in the mother is a powerful tool for diagnosis in the neonate, but physicians need to make mandatory steps to consider maternal TB in countries where the incidence is high. In this report we present two newborns with perinatal TB, the different clinical aspects in their mothers, and the problems that arised during investigation and diagnosis. We emphasize the need for improvement regarding screening of women at risk and sensitization of the medical community about this entity. We need to think in TB.

Published in	International Journal of Infectious Diseases and Therapy (Volume 2, Issue 1)
DOI	10.11648/j.ijidt.20170201.15
Page(s)	22-24
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Perinatal Tuberculosis, Mycobacterium Tuberculosis, Tuberculosis Control, Vertical Infection, Maternal-Fetal Infection

References

[1]	Tiemersma EW, Van der Werf M, Borgdorff MW, Williams BG, Nagelkerke NJ. Natural history of tuberculosis: duration and fatality of untreated pulmonary tuberculosis in HIVnegative patients: A systematic review. PLoS ONE 2011 6 (4): e17601.
[2]	Loto OM, Awowole I. Tuberculosis in Pregnancy: A Review. Journal of Pregnancy. 2012; 2012: 379-271. doi:10.1155/2012/379271.
[3]	National Institute of Respiratory Diseases (INER) “Emilio Coni”, National Administration of Laboratories and Health Institutes (ANLIS), 2012. http://www.anlis.gov.ar/inst/INER/.
[4]	Cantwell MF, Shehab ZM, Costello AM, Sands L, Green LF, Ewing EP, et al. Congenital Tuberculosis. N Engl J Med 1994; 330: 1051-1054.
[5]	Singh M, Kothur K, Dayal D, Kusuma S. Perinatal tuberculosis: a case series. J Trop Pediatr 2007; 53: 135–138.
[6]	Surve TY, Malkani M, Mhatre A, Samdani VP Congenital TB associated with asymptomatic maternal endometrial TB Trop Doct. 2006 Jan;36 (1): 59-61.
[7]	Olabisi M. Loto and Ibraheem Awowole, “Tuberculosis in Pregnancy: A Review,” Journal of Pregnancy, vol. 2012, Article ID 379271, 7 pages, 2012. doi:10.1155/2012/379271.
[8]	Whittaker E, Kampmann B. Perinatal tuberculosis New challenges in the diagnosis and treatment of tuberculosis in infants and the newborn. Early Human Development 2008; 84: 795–799.
[9]	Espiritu N, Aguirre L, Jave O, Sanchez L, Kirwan DE, Gilman RH. Congenital Transmission of Multidrug-Resistant Tuberculosis. Am J Trop Med Hyg 2014; 91 (1): 92–95.
[10]	Baquero-Artigao F, Mellado Peña MJ, Del Rosal Rabes T, Noguera Julián A, Goncé Mellgren A, de la Calle Fernández-Miranda M, Navarro Gómez ML; Working Group on gestational, congenital, and postnatal tuberculosis, Spanish Society of Pediatric Infectious Diseases (PFIC). Spanish Society for Pediatric Infectious Diseases guidelines on tuberculosis in pregnant women and neonates: Epidemiology and diagnosis. Congenital tuberculosis. An Pediatr (Barc). 2015 Oct;83 (4): 285.e1-8. doi: 10.1016/j.anpedi.2015.01.004.

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APA Style

Eduardo Alfredo Duro, Elizabeth Marcela Rizzo. (2017). Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers. International Journal of Infectious Diseases and Therapy, 2(1), 22-24. https://doi.org/10.11648/j.ijidt.20170201.15

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ACS Style

Eduardo Alfredo Duro; Elizabeth Marcela Rizzo. Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers. Int. J. Infect. Dis. Ther. 2017, 2(1), 22-24. doi: 10.11648/j.ijidt.20170201.15

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AMA Style

Eduardo Alfredo Duro, Elizabeth Marcela Rizzo. Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers. Int J Infect Dis Ther. 2017;2(1):22-24. doi: 10.11648/j.ijidt.20170201.15

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@article{10.11648/j.ijidt.20170201.15,
  author = {Eduardo Alfredo Duro and Elizabeth Marcela Rizzo},
  title = {Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {2},
  number = {1},
  pages = {22-24},
  doi = {10.11648/j.ijidt.20170201.15},
  url = {https://doi.org/10.11648/j.ijidt.20170201.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20170201.15},
  abstract = {The diagnosis of tuberculosis (TB) in a newborn is often difficult as clinical signs are nonspecific. Neonatal infection is rare but it has a mortality up to 50%. The suspicion of TB in the mother is a powerful tool for diagnosis in the neonate, but physicians need to make mandatory steps to consider maternal TB in countries where the incidence is high. In this report we present two newborns with perinatal TB, the different clinical aspects in their mothers, and the problems that arised during investigation and diagnosis. We emphasize the need for improvement regarding screening of women at risk and sensitization of the medical community about this entity. We need to think in TB.},
 year = {2017}
}

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TY  - JOUR
T1  - Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers
AU  - Eduardo Alfredo Duro
AU  - Elizabeth Marcela Rizzo
Y1  - 2017/02/24
PY  - 2017
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DO  - 10.11648/j.ijidt.20170201.15
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
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AB  - The diagnosis of tuberculosis (TB) in a newborn is often difficult as clinical signs are nonspecific. Neonatal infection is rare but it has a mortality up to 50%. The suspicion of TB in the mother is a powerful tool for diagnosis in the neonate, but physicians need to make mandatory steps to consider maternal TB in countries where the incidence is high. In this report we present two newborns with perinatal TB, the different clinical aspects in their mothers, and the problems that arised during investigation and diagnosis. We emphasize the need for improvement regarding screening of women at risk and sensitization of the medical community about this entity. We need to think in TB.
VL  - 2
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Author Information

Eduardo Alfredo Duro

Faculty of Health Sciences, University of Moron, Buenos Aires, Argentina
Elizabeth Marcela Rizzo

Magdalena V de Martínez General Hospital, Buenos Aires, Argentina

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APA Style

Eduardo Alfredo Duro, Elizabeth Marcela Rizzo. (2017). Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers. International Journal of Infectious Diseases and Therapy, 2(1), 22-24. https://doi.org/10.11648/j.ijidt.20170201.15

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ACS Style

Eduardo Alfredo Duro; Elizabeth Marcela Rizzo. Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers. Int. J. Infect. Dis. Ther. 2017, 2(1), 22-24. doi: 10.11648/j.ijidt.20170201.15

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AMA Style

Eduardo Alfredo Duro, Elizabeth Marcela Rizzo. Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers. Int J Infect Dis Ther. 2017;2(1):22-24. doi: 10.11648/j.ijidt.20170201.15

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@article{10.11648/j.ijidt.20170201.15,
  author = {Eduardo Alfredo Duro and Elizabeth Marcela Rizzo},
  title = {Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {2},
  number = {1},
  pages = {22-24},
  doi = {10.11648/j.ijidt.20170201.15},
  url = {https://doi.org/10.11648/j.ijidt.20170201.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20170201.15},
  abstract = {The diagnosis of tuberculosis (TB) in a newborn is often difficult as clinical signs are nonspecific. Neonatal infection is rare but it has a mortality up to 50%. The suspicion of TB in the mother is a powerful tool for diagnosis in the neonate, but physicians need to make mandatory steps to consider maternal TB in countries where the incidence is high. In this report we present two newborns with perinatal TB, the different clinical aspects in their mothers, and the problems that arised during investigation and diagnosis. We emphasize the need for improvement regarding screening of women at risk and sensitization of the medical community about this entity. We need to think in TB.},
 year = {2017}
}

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TY  - JOUR
T1  - Early Diagnosis and Treatment Problems with Perinatal Tuberculosis as a Challenge to Health Care Providers
AU  - Eduardo Alfredo Duro
AU  - Elizabeth Marcela Rizzo
Y1  - 2017/02/24
PY  - 2017
N1  - https://doi.org/10.11648/j.ijidt.20170201.15
DO  - 10.11648/j.ijidt.20170201.15
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 22
EP  - 24
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20170201.15
AB  - The diagnosis of tuberculosis (TB) in a newborn is often difficult as clinical signs are nonspecific. Neonatal infection is rare but it has a mortality up to 50%. The suspicion of TB in the mother is a powerful tool for diagnosis in the neonate, but physicians need to make mandatory steps to consider maternal TB in countries where the incidence is high. In this report we present two newborns with perinatal TB, the different clinical aspects in their mothers, and the problems that arised during investigation and diagnosis. We emphasize the need for improvement regarding screening of women at risk and sensitization of the medical community about this entity. We need to think in TB.
VL  - 2
IS  - 1
ER  -

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