Antibiotic Susceptibility Pattern of <i>Pseudomonas aeruginosa</i> Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India

Suresh Babu

doi:doi:10.11648/j.ijidt.20180302.12

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Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India

Suresh Babu

Published in International Journal of Infectious Diseases and Therapy (Volume 3, Issue 2)

Received: 4 May 2018 Accepted: 14 June 2018 Published: 9 July 2018

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Abstract

Multiple antibiotic resistance in bacterial populations is a pervasive and growing clinical problem, which is recognized as a threat to public health. Drug resistance to Pseudomonas sp. has spread to such a level irrespective of the type of patients, that, its pattern of distribution and antibiotic resistance needs to be studied in detail, especially in trauma patients. Of the Gram negative bacilli, Pseudomonas aeruginosa has been of particular interest, the incidence of which in wound infection has increased compared to a decade back. The objective of this study was to know the antibiotic susceptibility pattern of Pseudomonas aeruginosa isolates from wound infections. Out of the total of 1404 cases from which pus samples collected, 204 (14.5%) yielded Pseudomonas aeruginosa isolates. Among the antibiotics tested, Imipenem was the most sensitive drug, showing susceptibility in 81.3% of the isolates, followed by Piperacillin + tazobactam (76.4%), Meropenem (70.5%) and Piperacillin (67.6%). Fifteen (7.4%) multidrug resistant strains were reported out of the 204 isolations. Increase in resistance to aminoglycosides and fluoroquinolones in this study, prompted evaluation of antibiotic susceptibility pattern of Pseudomonas isolates from clinical samples at regular intervals.

Published in	International Journal of Infectious Diseases and Therapy (Volume 3, Issue 2)
DOI	10.11648/j.ijidt.20180302.12
Page(s)	30-33
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Pseudomonas aeruginosa, Multiple Drug Resistance, Wound Infections, Gram Negative Bacilli

References

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[4]	Ganjam Shrivastava, GS Bhatambare, A Lunavat, KB Patel, T Maheshwari. Pattern of microorganisms from burn wounds and their trends of susceptibility to antibiotics in tertiary care centre. Int J of Health System and Disaster Management 2016; 4(2):53-57.
[5]	Vivek Kulkami, Sagar Mohan Arati, YM Jayaraj, Channappa T Shivannavar, MR Joshi. Bacterial etiology and their biogram in burn wound infections at Kalaburgi region (India). Ind J Burns 2015; 23(1):65-70.
[6]	Richa Gupta, Abida Malik, Meher Rizvi, Moied Ahmed. Presence of metallo beta lactamases (MBL), ESBL Amp C positive non- fermenting gram negative bacilli among intensive care unit patients with special reference to molecular detection of bla CTX-M and bla Amp C genes. Ind J Med Res. 2016; 144(2):271-275.
[7]	Sapana G Mundhada, Prakash H Waghmare, Prachala G Rathod, Kishore V Ingole. Bacterial and fungal profile of burn wound infections in tertiary care centre. Ind J Burns. 2015; 23(1):71-75.
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APA Style

Suresh Babu. (2018). Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India. International Journal of Infectious Diseases and Therapy, 3(2), 30-33. https://doi.org/10.11648/j.ijidt.20180302.12

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ACS Style

Suresh Babu. Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India. Int. J. Infect. Dis. Ther. 2018, 3(2), 30-33. doi: 10.11648/j.ijidt.20180302.12

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AMA Style

Suresh Babu. Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India. Int J Infect Dis Ther. 2018;3(2):30-33. doi: 10.11648/j.ijidt.20180302.12

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@article{10.11648/j.ijidt.20180302.12,
  author = {Suresh Babu},
  title = {Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {3},
  number = {2},
  pages = {30-33},
  doi = {10.11648/j.ijidt.20180302.12},
  url = {https://doi.org/10.11648/j.ijidt.20180302.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20180302.12},
  abstract = {Multiple antibiotic resistance in bacterial populations is a pervasive and growing clinical problem, which is recognized as a threat to public health. Drug resistance to Pseudomonas sp. has spread to such a level irrespective of the type of patients, that, its pattern of distribution and antibiotic resistance needs to be studied in detail, especially in trauma patients. Of the Gram negative bacilli, Pseudomonas aeruginosa has been of particular interest, the incidence of which in wound infection has increased compared to a decade back. The objective of this study was to know the antibiotic susceptibility pattern of Pseudomonas aeruginosa isolates from wound infections. Out of the total of 1404 cases from which pus samples collected, 204 (14.5%) yielded Pseudomonas aeruginosa isolates. Among the antibiotics tested, Imipenem was the most sensitive drug, showing susceptibility in 81.3% of the isolates, followed by Piperacillin + tazobactam (76.4%), Meropenem (70.5%) and Piperacillin (67.6%). Fifteen (7.4%) multidrug resistant strains were reported out of the 204 isolations. Increase in resistance to aminoglycosides and fluoroquinolones in this study, prompted evaluation of antibiotic susceptibility pattern of Pseudomonas isolates from clinical samples at regular intervals.},
 year = {2018}
}

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TY  - JOUR
T1  - Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India
AU  - Suresh Babu
Y1  - 2018/07/09
PY  - 2018
N1  - https://doi.org/10.11648/j.ijidt.20180302.12
DO  - 10.11648/j.ijidt.20180302.12
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 30
EP  - 33
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20180302.12
AB  - Multiple antibiotic resistance in bacterial populations is a pervasive and growing clinical problem, which is recognized as a threat to public health. Drug resistance to Pseudomonas sp. has spread to such a level irrespective of the type of patients, that, its pattern of distribution and antibiotic resistance needs to be studied in detail, especially in trauma patients. Of the Gram negative bacilli, Pseudomonas aeruginosa has been of particular interest, the incidence of which in wound infection has increased compared to a decade back. The objective of this study was to know the antibiotic susceptibility pattern of Pseudomonas aeruginosa isolates from wound infections. Out of the total of 1404 cases from which pus samples collected, 204 (14.5%) yielded Pseudomonas aeruginosa isolates. Among the antibiotics tested, Imipenem was the most sensitive drug, showing susceptibility in 81.3% of the isolates, followed by Piperacillin + tazobactam (76.4%), Meropenem (70.5%) and Piperacillin (67.6%). Fifteen (7.4%) multidrug resistant strains were reported out of the 204 isolations. Increase in resistance to aminoglycosides and fluoroquinolones in this study, prompted evaluation of antibiotic susceptibility pattern of Pseudomonas isolates from clinical samples at regular intervals.
VL  - 3
IS  - 2
ER  -

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Author Information

Suresh Babu

Department of Microbiology, Dr SM CSI Medical College and Hospital, Trivandrum, India

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Plain Text BibTeX RIS

APA Style

Suresh Babu. (2018). Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India. International Journal of Infectious Diseases and Therapy, 3(2), 30-33. https://doi.org/10.11648/j.ijidt.20180302.12

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ACS Style

Suresh Babu. Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India. Int. J. Infect. Dis. Ther. 2018, 3(2), 30-33. doi: 10.11648/j.ijidt.20180302.12

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AMA Style

Suresh Babu. Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India. Int J Infect Dis Ther. 2018;3(2):30-33. doi: 10.11648/j.ijidt.20180302.12

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@article{10.11648/j.ijidt.20180302.12,
  author = {Suresh Babu},
  title = {Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {3},
  number = {2},
  pages = {30-33},
  doi = {10.11648/j.ijidt.20180302.12},
  url = {https://doi.org/10.11648/j.ijidt.20180302.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20180302.12},
  abstract = {Multiple antibiotic resistance in bacterial populations is a pervasive and growing clinical problem, which is recognized as a threat to public health. Drug resistance to Pseudomonas sp. has spread to such a level irrespective of the type of patients, that, its pattern of distribution and antibiotic resistance needs to be studied in detail, especially in trauma patients. Of the Gram negative bacilli, Pseudomonas aeruginosa has been of particular interest, the incidence of which in wound infection has increased compared to a decade back. The objective of this study was to know the antibiotic susceptibility pattern of Pseudomonas aeruginosa isolates from wound infections. Out of the total of 1404 cases from which pus samples collected, 204 (14.5%) yielded Pseudomonas aeruginosa isolates. Among the antibiotics tested, Imipenem was the most sensitive drug, showing susceptibility in 81.3% of the isolates, followed by Piperacillin + tazobactam (76.4%), Meropenem (70.5%) and Piperacillin (67.6%). Fifteen (7.4%) multidrug resistant strains were reported out of the 204 isolations. Increase in resistance to aminoglycosides and fluoroquinolones in this study, prompted evaluation of antibiotic susceptibility pattern of Pseudomonas isolates from clinical samples at regular intervals.},
 year = {2018}
}

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TY  - JOUR
T1  - Antibiotic Susceptibility Pattern of Pseudomonas aeruginosa Isolates from Wound Infections in a Tertiary Care Centre in South Kerala, India
AU  - Suresh Babu
Y1  - 2018/07/09
PY  - 2018
N1  - https://doi.org/10.11648/j.ijidt.20180302.12
DO  - 10.11648/j.ijidt.20180302.12
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 30
EP  - 33
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20180302.12
AB  - Multiple antibiotic resistance in bacterial populations is a pervasive and growing clinical problem, which is recognized as a threat to public health. Drug resistance to Pseudomonas sp. has spread to such a level irrespective of the type of patients, that, its pattern of distribution and antibiotic resistance needs to be studied in detail, especially in trauma patients. Of the Gram negative bacilli, Pseudomonas aeruginosa has been of particular interest, the incidence of which in wound infection has increased compared to a decade back. The objective of this study was to know the antibiotic susceptibility pattern of Pseudomonas aeruginosa isolates from wound infections. Out of the total of 1404 cases from which pus samples collected, 204 (14.5%) yielded Pseudomonas aeruginosa isolates. Among the antibiotics tested, Imipenem was the most sensitive drug, showing susceptibility in 81.3% of the isolates, followed by Piperacillin + tazobactam (76.4%), Meropenem (70.5%) and Piperacillin (67.6%). Fifteen (7.4%) multidrug resistant strains were reported out of the 204 isolations. Increase in resistance to aminoglycosides and fluoroquinolones in this study, prompted evaluation of antibiotic susceptibility pattern of Pseudomonas isolates from clinical samples at regular intervals.
VL  - 3
IS  - 2
ER  -

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