Measles is a highly contagious acute febrile eruptive disease. It can be prevented through vaccination. The aim of this study was to determine the epidemiological, clinical, and therapeutic features of measles cases hospitalized at Point "G" University Teaching Hospital. It was a retrospective study to review the medical files of patients hospitalized for measles between January 2010 and May 2011 at the Infectious Diseases Department of the Point "G" University Teaching Hospital. During the study period, 31 patients (6.4%) were treated for measles, and the majority of cases were seen in April months (20 cases) and May months (5 cases). The most affected age group was 9 - 59 months (58.1%) with a sex ratio of 1.38. The majority of patients (64.5%) consulted at least two health facilities before their hospitalization in Point “G” with an average of 5.3 ± 3.6 days from unset to the hospitalization. Measles immunization was not effective in 16 out of 26 patients and nearly one-third (29.0%) had familial contact measles case. Febrile rash, present in all patients, was associated with cough (96.8%), rhinitis (77.4%) and/or conjunctivitis (77.4%). Pneumonia was the most common complication (83.9%) followed by comorbidities such as gastroenteritis (29%), malnutrition (9.7%) and oral candidiasis (9.7%). Amoxicillin and ceftriaxone were the antibiotics frequently used against complications. Patients were hospitalized for an average of 6.9 ± 4.2 days, and no death was recorded. This study revealed that pneumonia was the main complication leading to hospitalization of patients. For a better control of measles, we need to fully respect the immunization schedule which is a guarantee for vaccine efficacy.
Published in | International Journal of Infectious Diseases and Therapy (Volume 4, Issue 3) |
DOI | 10.11648/j.ijidt.20190403.13 |
Page(s) | 44-49 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Bamako, Clinical, Epidemiology, Therapeutic, Complications, Measles
[1] | Moss WJ. Measles. The Lancet. 2017; 390 (10111): 2490-502. |
[2] | Byberg S, Thysen SM, Rodrigues A, Martins C, Cabral C, Careme M, et al. A general measles vaccination campaign in urban Guinea-Bissau: Comparing child mortality among participants and non-participants. Vaccine. 2017; 351: 33-9. |
[3] | WHO. Measles [Internet]. WHO; 2018. Available on: https://www.who.int/news-room/fact-sheets/detail/meales [accessed 12 december 2018]. |
[4] | Saleh J-E. Trends of measles in Nigeria: A systematic review. Sahel Medical Journal. 2016; 19 (1): 5-11. |
[5] | OMS. Élimination de la rougeole d’ici 2020: Stratégie pour la Région africaine. In 61ème session du Comité régional de l’OMS pour l’Afrique, Yamoussoukro, Côte d’Ivoire, 29 août - 2 septembre 2011. OMS, Bureau régional de l’Afrique; 2011. |
[6] | Ministère de la santé. Plan stratégique d’élimination de la rougeole au Mali (2013 - 2020) [Internet]. Direction nationale de la Santé; 2013. Available on: http://www.nationalplanningcycles.org/sites/default/files/planning_cycle_repository/mali/plan_strategique_elimination_rougeole_sikasso_mali_2013_2020_21-08-013_vf_0.pdf [accessed 1 may 2018]. |
[7] | Kertesz DA, Touré K, Berthé A, Konaté Y, Bougoudogo F. Evaluation of Urban Measles Mass Campaigns for Children Aged 9–59 Months in Mali. The Journal of Infectious Diseases. 2003; 187 (Suppl 1): 69-73. |
[8] | OMS. Le traitement de la rougeole chez l’enfant. WHO/EPI/TRAM/97.02; 2004. |
[9] | Camara B, Diouf S, Diagne I, Tall Dia A, Fall L, Ba M, et al. Complications de la rougeole et facteurs de risque de décès. Médecine d’Afrique Noire. 2000; 47 (8/9): 380-5. |
[10] | Sezuo K, Yusuf T, Ibitoye P, Sanni M, Jiya N, Sani U, et al. A 5-year review of measles cases admitted into the emergency paediatric unit of a tertiary hospital in Sokoto, North-Western Nigeria. Sahel Medical Journal. 2018; 21 (3): 122-7. |
[11] | Onyiriuka AN. Clinical profile of children presenting with measles in a Nigerian secondary health-care institution. Journal of Infectious Diseases and Immunity. 2011; 3 (6): 112-6. |
[12] | Imperato PJ. Traditional attitudes towards measles in the Republic of Mali. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1969; 63 (6): 768-80. |
[13] | Aliyu I. Clinical findings and outcome of measles outbreak in an African city. Sifa Med J. 2016; 3 (1): 1-4. |
[14] | Fourn L, Fayomi E, Zohoun T. Rougeole: un défi pour le programme élargi de vaccination au Bénin. Médecine d’Afrique Noire. 1998; 45 (1): 6-8. |
[15] | Sume GE, Fouda AAB, Kobela M, Nguelé S, Emah I, Atem P, et al. Epidemiology and clinical characteristics of the Measles outbreak in the Nylon Health District, Douala Cameroon: a retrospective descriptive cross sectional study. Pan Afr Med J. 2012; 13: 66. |
[16] | Djadou K, Wateba M, Tchagbele O, Agbèrè A-D, Saka D, Atakouma Y. Aspects actuels de la rougeole dans le service de pédiatrie au CHR de Tsévié (CHR-T), de 2010 à 2012. Rev CAMES SANTE. 2013; 1 (2): 90-2. |
[17] | Doutchi M, Mohamed A-AO, Sayadi S, Sibongwere D, Shepherd S, Nafissa OM, et al. Campagne de vaccination contre la rougeole en période de pic épidémique dans une zone à forte prévalence de malnutrition au Niger: cas du district sanitaire de Mirriah (Zinder). Pan African Medical Journal. 2017; 27: 240. doi: 10.11604/pamj.2017.27.240.11881. |
[18] | Goodson JL, Masresha BG, Wannemuehler K, Uzicanin A, Cochi S. Changing Epidemiology of Measles in Africa. Journal of Infectious Diseases. 2011; 204 (Suppl 1): 205-14. |
[19] | Seck I, Faye A, Mbacké Leye MM, Bathily A, Diagne-Camara M, Ndiaye P, et al. Épidémie de rougeole et de sa riposte en 2009, dans la région de Dakar, Sénégal. Santé Publique. 2012; 24 (2): 121. |
[20] | Boushab BM, Savadogo M, Sow MS, Dao S. Epidemiological, clinical, and prognostic study of the measles in the Aioun regional hospital in Mauritania. Médecine et Santé Tropicales. 2015; 4-5-6; (2): 180-3. |
[21] | Kabra SK, Lodha R. Antibiotics for preventing complications in children with measles. In: The Cochrane Collaboration, éditeur. Cochrane Database of Systematic Reviews [Internet]. Chichester, UK: John Wiley & Sons, Ltd; 2008. Available on: http://doi.wiley.com/10.1002/14651858.CD001477.pub3 [accessed 14 November 2018]. |
APA Style
Mikaila Kabore, Issa Konate, Yacouba Cissoko, Bassirou Diarra, Jean Paul Dembele, et al. (2019). Measles in Bamako: Epidemiological, Clinical and Therapeutic Features of Patients Hospitalized at University Teaching Hospital of Point "G". International Journal of Infectious Diseases and Therapy, 4(3), 44-49. https://doi.org/10.11648/j.ijidt.20190403.13
ACS Style
Mikaila Kabore; Issa Konate; Yacouba Cissoko; Bassirou Diarra; Jean Paul Dembele, et al. Measles in Bamako: Epidemiological, Clinical and Therapeutic Features of Patients Hospitalized at University Teaching Hospital of Point "G". Int. J. Infect. Dis. Ther. 2019, 4(3), 44-49. doi: 10.11648/j.ijidt.20190403.13
AMA Style
Mikaila Kabore, Issa Konate, Yacouba Cissoko, Bassirou Diarra, Jean Paul Dembele, et al. Measles in Bamako: Epidemiological, Clinical and Therapeutic Features of Patients Hospitalized at University Teaching Hospital of Point "G". Int J Infect Dis Ther. 2019;4(3):44-49. doi: 10.11648/j.ijidt.20190403.13
@article{10.11648/j.ijidt.20190403.13, author = {Mikaila Kabore and Issa Konate and Yacouba Cissoko and Bassirou Diarra and Jean Paul Dembele and Mariam Soumare and Assetou Fofana and Abdoulaye Zare and Hermine Meli and Mohamed Aly Cisse and Dramane Sogoba and Oumar Magassouba and Madou Traore and Kongnimissom Apoline Sondo and Sounkalo Dao}, title = {Measles in Bamako: Epidemiological, Clinical and Therapeutic Features of Patients Hospitalized at University Teaching Hospital of Point "G"}, journal = {International Journal of Infectious Diseases and Therapy}, volume = {4}, number = {3}, pages = {44-49}, doi = {10.11648/j.ijidt.20190403.13}, url = {https://doi.org/10.11648/j.ijidt.20190403.13}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20190403.13}, abstract = {Measles is a highly contagious acute febrile eruptive disease. It can be prevented through vaccination. The aim of this study was to determine the epidemiological, clinical, and therapeutic features of measles cases hospitalized at Point "G" University Teaching Hospital. It was a retrospective study to review the medical files of patients hospitalized for measles between January 2010 and May 2011 at the Infectious Diseases Department of the Point "G" University Teaching Hospital. During the study period, 31 patients (6.4%) were treated for measles, and the majority of cases were seen in April months (20 cases) and May months (5 cases). The most affected age group was 9 - 59 months (58.1%) with a sex ratio of 1.38. The majority of patients (64.5%) consulted at least two health facilities before their hospitalization in Point “G” with an average of 5.3 ± 3.6 days from unset to the hospitalization. Measles immunization was not effective in 16 out of 26 patients and nearly one-third (29.0%) had familial contact measles case. Febrile rash, present in all patients, was associated with cough (96.8%), rhinitis (77.4%) and/or conjunctivitis (77.4%). Pneumonia was the most common complication (83.9%) followed by comorbidities such as gastroenteritis (29%), malnutrition (9.7%) and oral candidiasis (9.7%). Amoxicillin and ceftriaxone were the antibiotics frequently used against complications. Patients were hospitalized for an average of 6.9 ± 4.2 days, and no death was recorded. This study revealed that pneumonia was the main complication leading to hospitalization of patients. For a better control of measles, we need to fully respect the immunization schedule which is a guarantee for vaccine efficacy.}, year = {2019} }
TY - JOUR T1 - Measles in Bamako: Epidemiological, Clinical and Therapeutic Features of Patients Hospitalized at University Teaching Hospital of Point "G" AU - Mikaila Kabore AU - Issa Konate AU - Yacouba Cissoko AU - Bassirou Diarra AU - Jean Paul Dembele AU - Mariam Soumare AU - Assetou Fofana AU - Abdoulaye Zare AU - Hermine Meli AU - Mohamed Aly Cisse AU - Dramane Sogoba AU - Oumar Magassouba AU - Madou Traore AU - Kongnimissom Apoline Sondo AU - Sounkalo Dao Y1 - 2019/09/19 PY - 2019 N1 - https://doi.org/10.11648/j.ijidt.20190403.13 DO - 10.11648/j.ijidt.20190403.13 T2 - International Journal of Infectious Diseases and Therapy JF - International Journal of Infectious Diseases and Therapy JO - International Journal of Infectious Diseases and Therapy SP - 44 EP - 49 PB - Science Publishing Group SN - 2578-966X UR - https://doi.org/10.11648/j.ijidt.20190403.13 AB - Measles is a highly contagious acute febrile eruptive disease. It can be prevented through vaccination. The aim of this study was to determine the epidemiological, clinical, and therapeutic features of measles cases hospitalized at Point "G" University Teaching Hospital. It was a retrospective study to review the medical files of patients hospitalized for measles between January 2010 and May 2011 at the Infectious Diseases Department of the Point "G" University Teaching Hospital. During the study period, 31 patients (6.4%) were treated for measles, and the majority of cases were seen in April months (20 cases) and May months (5 cases). The most affected age group was 9 - 59 months (58.1%) with a sex ratio of 1.38. The majority of patients (64.5%) consulted at least two health facilities before their hospitalization in Point “G” with an average of 5.3 ± 3.6 days from unset to the hospitalization. Measles immunization was not effective in 16 out of 26 patients and nearly one-third (29.0%) had familial contact measles case. Febrile rash, present in all patients, was associated with cough (96.8%), rhinitis (77.4%) and/or conjunctivitis (77.4%). Pneumonia was the most common complication (83.9%) followed by comorbidities such as gastroenteritis (29%), malnutrition (9.7%) and oral candidiasis (9.7%). Amoxicillin and ceftriaxone were the antibiotics frequently used against complications. Patients were hospitalized for an average of 6.9 ± 4.2 days, and no death was recorded. This study revealed that pneumonia was the main complication leading to hospitalization of patients. For a better control of measles, we need to fully respect the immunization schedule which is a guarantee for vaccine efficacy. VL - 4 IS - 3 ER -