@article{10.11648/j.ijidt.20210604.17,
  author = {Angèle Azon Kouanou and Yolande Sissinto Savi De Tovè and Agbodandé Kouessi Anthelme and Adélakoun Ange Géoffroy Falade and Yves Morel Sokadjo and Mahoutin Semassa Ghislain Missiho and Olamidé Gloria Marlene Marie Dénise Kouanou and Marcelle Vodounou and Richard Oba and Djimon Marcel Zannou},
  title = {Diagnostic and Therapeutic Difficulties of Chronic Diarrhea with Cystoisospora belli Inaugural Infection by the HIV at the NTHC-HKM of Cotonou: Literature Review},
  journal = {International Journal of Infectious Diseases and Therapy},
  volume = {6},
  number = {4},
  pages = {161-164},
  doi = {10.11648/j.ijidt.20210604.17},
  url = {https://doi.org/10.11648/j.ijidt.20210604.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijidt.20210604.17},
  abstract = {Isosporosis is an opportunistic parasitosis caused by Cystoisospora belli. It was more or less frequently found during HIV immunodepression. Its prevalence has considerably decreased since the democratization of antiretroviral treatments and the implementation of a strategy of systematic global management of People Living with HIV (PLWH) and opportunistic infections. We report the case of a 49-year-old PLHIV patient discovered during the exploration of recurrent diarrhea. This diarrhea was found to be due to Cystoisospora belli. The patient was allergic to cotrimoxazole and was therefore initially treated with ciprofloxacin and tinidazole with poor evolution. The other treatments selected are limited by the lack of access to drugs, both geographically and financially. In view of the persistence of the clinical picture and the continuous presence of the parasite in the stools, several hypotheses have been put forward. That of an under-dosage of the molecule used, of a lack of therapeutic compliance, or of the resistance of the germ to the prescribed molecule. Although the coproculture and antibiogram revealed the sensitivity of the germ to the Ciprofloxacin already prescribed, and to the Cotrimoxazole to which the patient is very allergic, and which can therefore no longer be prescribed. After a second opinion and a review of the literature, the patient was put on Pyrimethamine tablets and Albendazole with folic acid. The evolution was favorable with a significant regression of stools, resumption of appetite, and weight gain after one month. A last coproculture of control did not find any more oocysts of cystoisospora belli. In the face of chronic diarrhea, the systematic search for opportunistic germs in PLWHIV is essential. Management is possible.},
 year = {2021}
}

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TY  - JOUR
T1  - Diagnostic and Therapeutic Difficulties of Chronic Diarrhea with Cystoisospora belli Inaugural Infection by the HIV at the NTHC-HKM of Cotonou: Literature Review
AU  - Angèle Azon Kouanou
AU  - Yolande Sissinto Savi De Tovè
AU  - Agbodandé Kouessi Anthelme
AU  - Adélakoun Ange Géoffroy Falade
AU  - Yves Morel Sokadjo
AU  - Mahoutin Semassa Ghislain Missiho
AU  - Olamidé Gloria Marlene Marie Dénise Kouanou
AU  - Marcelle Vodounou
AU  - Richard Oba
AU  - Djimon Marcel Zannou
Y1  - 2021/12/29
PY  - 2021
N1  - https://doi.org/10.11648/j.ijidt.20210604.17
DO  - 10.11648/j.ijidt.20210604.17
T2  - International Journal of Infectious Diseases and Therapy
JF  - International Journal of Infectious Diseases and Therapy
JO  - International Journal of Infectious Diseases and Therapy
SP  - 161
EP  - 164
PB  - Science Publishing Group
SN  - 2578-966X
UR  - https://doi.org/10.11648/j.ijidt.20210604.17
AB  - Isosporosis is an opportunistic parasitosis caused by Cystoisospora belli. It was more or less frequently found during HIV immunodepression. Its prevalence has considerably decreased since the democratization of antiretroviral treatments and the implementation of a strategy of systematic global management of People Living with HIV (PLWH) and opportunistic infections. We report the case of a 49-year-old PLHIV patient discovered during the exploration of recurrent diarrhea. This diarrhea was found to be due to Cystoisospora belli. The patient was allergic to cotrimoxazole and was therefore initially treated with ciprofloxacin and tinidazole with poor evolution. The other treatments selected are limited by the lack of access to drugs, both geographically and financially. In view of the persistence of the clinical picture and the continuous presence of the parasite in the stools, several hypotheses have been put forward. That of an under-dosage of the molecule used, of a lack of therapeutic compliance, or of the resistance of the germ to the prescribed molecule. Although the coproculture and antibiogram revealed the sensitivity of the germ to the Ciprofloxacin already prescribed, and to the Cotrimoxazole to which the patient is very allergic, and which can therefore no longer be prescribed. After a second opinion and a review of the literature, the patient was put on Pyrimethamine tablets and Albendazole with folic acid. The evolution was favorable with a significant regression of stools, resumption of appetite, and weight gain after one month. A last coproculture of control did not find any more oocysts of cystoisospora belli. In the face of chronic diarrhea, the systematic search for opportunistic germs in PLWHIV is essential. Management is possible.
VL  - 6
IS  - 4
ER  - 

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