Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer

Liyang Hu; Lingling Lin; Zhongqiu Lu

doi:doi:10.11648/j.jctr.20231102.12

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Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer

Liyang Hu, Lingling Lin, Zhongqiu Lu

Published in Journal of Cancer Treatment and Research (Volume 11, Issue 2)

Received: 21 July 2023 Accepted: 7 August 2023 Published: 17 August 2023

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Abstract

Objective: To analyze the related factors of venous thromboembolism in patients with ovarian cancer. Methods: A total of 86 patients with ovarian cancer complicated with VTE who were treated in a hospital from January 2021 to December 2022 were selected. The medical records of the patients were collected. The revised Caprini risk assessment scale (version 2013) was used to evaluate the risk level of VTE in patients with ovarian cancer, and the risk factors of VTE in patients with ovarian cancer were analyzed. Results: According to the revised Caprini risk assessment scale, 86 patients were scored, including 23 cases (26.74%) of high risk and 62 cases (72.09%) of extremely high risk. Among 86 patients, 77 cases (89.53%) were epithelial cancer, 75 cases (87.21%) were poorly differentiated cancer, 71 cases (82.56%) were International Federation of Gynecology and Obstetrics (FIGO) stage III-IV, and 28 cases (32.56%) were complicated with ascites. Thrombosis occurred before neoadjuvant chemotherapy in 9 cases (10.47%), during neoadjuvant chemotherapy in 5 cases (5.81%), before surgery in 21 cases (24.42%), during surgery in 1 case (jugular vein thrombosis), and after surgery in 50 cases (58.14%). VTE occurred in 26 patients (30.26%) with central venous catheter implantation and 22 patients (25.58%) with lymph node metastasis. Conclusions: According to the modified Caprini risk assessment scale, high risk and very high risk ovarian cancer patients are at high risk of VTE. The modified Caprini risk assessment scale is helpful for clinical early identification of patients with high risk of VTE. Tumor histological type, tumor grade, tumor staging and surgical treatment are related to the occurrence of VTE in patients with ovarian cancer.

Published in	Journal of Cancer Treatment and Research (Volume 11, Issue 2)
DOI	10.11648/j.jctr.20231102.12
Page(s)	17-22
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ovarian Cancer, Venous Thromboembolism, Risk Factors, Tumor Histological Type, Tumor Grade, Tumor Staging

References

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APA Style

Liyang Hu, Lingling Lin, Zhongqiu Lu. (2023). Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer. Journal of Cancer Treatment and Research, 11(2), 17-22. https://doi.org/10.11648/j.jctr.20231102.12

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ACS Style

Liyang Hu; Lingling Lin; Zhongqiu Lu. Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer. J. Cancer Treat. Res. 2023, 11(2), 17-22. doi: 10.11648/j.jctr.20231102.12

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AMA Style

Liyang Hu, Lingling Lin, Zhongqiu Lu. Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer. J Cancer Treat Res. 2023;11(2):17-22. doi: 10.11648/j.jctr.20231102.12

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@article{10.11648/j.jctr.20231102.12,
  author = {Liyang Hu and Lingling Lin and Zhongqiu Lu},
  title = {Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer},
  journal = {Journal of Cancer Treatment and Research},
  volume = {11},
  number = {2},
  pages = {17-22},
  doi = {10.11648/j.jctr.20231102.12},
  url = {https://doi.org/10.11648/j.jctr.20231102.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20231102.12},
  abstract = {Objective: To analyze the related factors of venous thromboembolism in patients with ovarian cancer. Methods: A total of 86 patients with ovarian cancer complicated with VTE who were treated in a hospital from January 2021 to December 2022 were selected. The medical records of the patients were collected. The revised Caprini risk assessment scale (version 2013) was used to evaluate the risk level of VTE in patients with ovarian cancer, and the risk factors of VTE in patients with ovarian cancer were analyzed. Results: According to the revised Caprini risk assessment scale, 86 patients were scored, including 23 cases (26.74%) of high risk and 62 cases (72.09%) of extremely high risk. Among 86 patients, 77 cases (89.53%) were epithelial cancer, 75 cases (87.21%) were poorly differentiated cancer, 71 cases (82.56%) were International Federation of Gynecology and Obstetrics (FIGO) stage III-IV, and 28 cases (32.56%) were complicated with ascites. Thrombosis occurred before neoadjuvant chemotherapy in 9 cases (10.47%), during neoadjuvant chemotherapy in 5 cases (5.81%), before surgery in 21 cases (24.42%), during surgery in 1 case (jugular vein thrombosis), and after surgery in 50 cases (58.14%). VTE occurred in 26 patients (30.26%) with central venous catheter implantation and 22 patients (25.58%) with lymph node metastasis. Conclusions: According to the modified Caprini risk assessment scale, high risk and very high risk ovarian cancer patients are at high risk of VTE. The modified Caprini risk assessment scale is helpful for clinical early identification of patients with high risk of VTE. Tumor histological type, tumor grade, tumor staging and surgical treatment are related to the occurrence of VTE in patients with ovarian cancer.},
 year = {2023}
}

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TY  - JOUR
T1  - Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer
AU  - Liyang Hu
AU  - Lingling Lin
AU  - Zhongqiu Lu
Y1  - 2023/08/17
PY  - 2023
N1  - https://doi.org/10.11648/j.jctr.20231102.12
DO  - 10.11648/j.jctr.20231102.12
T2  - Journal of Cancer Treatment and Research
JF  - Journal of Cancer Treatment and Research
JO  - Journal of Cancer Treatment and Research
SP  - 17
EP  - 22
PB  - Science Publishing Group
SN  - 2376-7790
UR  - https://doi.org/10.11648/j.jctr.20231102.12
AB  - Objective: To analyze the related factors of venous thromboembolism in patients with ovarian cancer. Methods: A total of 86 patients with ovarian cancer complicated with VTE who were treated in a hospital from January 2021 to December 2022 were selected. The medical records of the patients were collected. The revised Caprini risk assessment scale (version 2013) was used to evaluate the risk level of VTE in patients with ovarian cancer, and the risk factors of VTE in patients with ovarian cancer were analyzed. Results: According to the revised Caprini risk assessment scale, 86 patients were scored, including 23 cases (26.74%) of high risk and 62 cases (72.09%) of extremely high risk. Among 86 patients, 77 cases (89.53%) were epithelial cancer, 75 cases (87.21%) were poorly differentiated cancer, 71 cases (82.56%) were International Federation of Gynecology and Obstetrics (FIGO) stage III-IV, and 28 cases (32.56%) were complicated with ascites. Thrombosis occurred before neoadjuvant chemotherapy in 9 cases (10.47%), during neoadjuvant chemotherapy in 5 cases (5.81%), before surgery in 21 cases (24.42%), during surgery in 1 case (jugular vein thrombosis), and after surgery in 50 cases (58.14%). VTE occurred in 26 patients (30.26%) with central venous catheter implantation and 22 patients (25.58%) with lymph node metastasis. Conclusions: According to the modified Caprini risk assessment scale, high risk and very high risk ovarian cancer patients are at high risk of VTE. The modified Caprini risk assessment scale is helpful for clinical early identification of patients with high risk of VTE. Tumor histological type, tumor grade, tumor staging and surgical treatment are related to the occurrence of VTE in patients with ovarian cancer.
VL  - 11
IS  - 2
ER  -

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Author Information

Liyang Hu

Department of Gynecology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Lingling Lin

Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Zhongqiu Lu

Department of Emergency, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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APA Style

Liyang Hu, Lingling Lin, Zhongqiu Lu. (2023). Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer. Journal of Cancer Treatment and Research, 11(2), 17-22. https://doi.org/10.11648/j.jctr.20231102.12

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ACS Style

Liyang Hu; Lingling Lin; Zhongqiu Lu. Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer. J. Cancer Treat. Res. 2023, 11(2), 17-22. doi: 10.11648/j.jctr.20231102.12

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AMA Style

Liyang Hu, Lingling Lin, Zhongqiu Lu. Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer. J Cancer Treat Res. 2023;11(2):17-22. doi: 10.11648/j.jctr.20231102.12

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@article{10.11648/j.jctr.20231102.12,
  author = {Liyang Hu and Lingling Lin and Zhongqiu Lu},
  title = {Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer},
  journal = {Journal of Cancer Treatment and Research},
  volume = {11},
  number = {2},
  pages = {17-22},
  doi = {10.11648/j.jctr.20231102.12},
  url = {https://doi.org/10.11648/j.jctr.20231102.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jctr.20231102.12},
  abstract = {Objective: To analyze the related factors of venous thromboembolism in patients with ovarian cancer. Methods: A total of 86 patients with ovarian cancer complicated with VTE who were treated in a hospital from January 2021 to December 2022 were selected. The medical records of the patients were collected. The revised Caprini risk assessment scale (version 2013) was used to evaluate the risk level of VTE in patients with ovarian cancer, and the risk factors of VTE in patients with ovarian cancer were analyzed. Results: According to the revised Caprini risk assessment scale, 86 patients were scored, including 23 cases (26.74%) of high risk and 62 cases (72.09%) of extremely high risk. Among 86 patients, 77 cases (89.53%) were epithelial cancer, 75 cases (87.21%) were poorly differentiated cancer, 71 cases (82.56%) were International Federation of Gynecology and Obstetrics (FIGO) stage III-IV, and 28 cases (32.56%) were complicated with ascites. Thrombosis occurred before neoadjuvant chemotherapy in 9 cases (10.47%), during neoadjuvant chemotherapy in 5 cases (5.81%), before surgery in 21 cases (24.42%), during surgery in 1 case (jugular vein thrombosis), and after surgery in 50 cases (58.14%). VTE occurred in 26 patients (30.26%) with central venous catheter implantation and 22 patients (25.58%) with lymph node metastasis. Conclusions: According to the modified Caprini risk assessment scale, high risk and very high risk ovarian cancer patients are at high risk of VTE. The modified Caprini risk assessment scale is helpful for clinical early identification of patients with high risk of VTE. Tumor histological type, tumor grade, tumor staging and surgical treatment are related to the occurrence of VTE in patients with ovarian cancer.},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer
AU  - Liyang Hu
AU  - Lingling Lin
AU  - Zhongqiu Lu
Y1  - 2023/08/17
PY  - 2023
N1  - https://doi.org/10.11648/j.jctr.20231102.12
DO  - 10.11648/j.jctr.20231102.12
T2  - Journal of Cancer Treatment and Research
JF  - Journal of Cancer Treatment and Research
JO  - Journal of Cancer Treatment and Research
SP  - 17
EP  - 22
PB  - Science Publishing Group
SN  - 2376-7790
UR  - https://doi.org/10.11648/j.jctr.20231102.12
AB  - Objective: To analyze the related factors of venous thromboembolism in patients with ovarian cancer. Methods: A total of 86 patients with ovarian cancer complicated with VTE who were treated in a hospital from January 2021 to December 2022 were selected. The medical records of the patients were collected. The revised Caprini risk assessment scale (version 2013) was used to evaluate the risk level of VTE in patients with ovarian cancer, and the risk factors of VTE in patients with ovarian cancer were analyzed. Results: According to the revised Caprini risk assessment scale, 86 patients were scored, including 23 cases (26.74%) of high risk and 62 cases (72.09%) of extremely high risk. Among 86 patients, 77 cases (89.53%) were epithelial cancer, 75 cases (87.21%) were poorly differentiated cancer, 71 cases (82.56%) were International Federation of Gynecology and Obstetrics (FIGO) stage III-IV, and 28 cases (32.56%) were complicated with ascites. Thrombosis occurred before neoadjuvant chemotherapy in 9 cases (10.47%), during neoadjuvant chemotherapy in 5 cases (5.81%), before surgery in 21 cases (24.42%), during surgery in 1 case (jugular vein thrombosis), and after surgery in 50 cases (58.14%). VTE occurred in 26 patients (30.26%) with central venous catheter implantation and 22 patients (25.58%) with lymph node metastasis. Conclusions: According to the modified Caprini risk assessment scale, high risk and very high risk ovarian cancer patients are at high risk of VTE. The modified Caprini risk assessment scale is helpful for clinical early identification of patients with high risk of VTE. Tumor histological type, tumor grade, tumor staging and surgical treatment are related to the occurrence of VTE in patients with ovarian cancer.
VL  - 11
IS  - 2
ER  -

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