If the catheter size, the thickness of a thread, the place for ligation were determined for the partial portal vein ligation (PPVL), the question of the suture material remains open. The aim of the study was to determine the optimal suture material (silk or prolene) for PPVL. The experiment was performed on 25 male adult outbred rats. The PPVL was carried out using the catheter 20G with thread 4-0. Portal pressure was measured before and 15 days after ligation. The measurements were performed by the differential manometer Testo 510 (Germany), which was connected to the catheter 24G, located in the distal part of the superior mesenteric vein. The animals were divided into two groups: the first group (n=12) – portal vein (PV) was ligated with silk, and the second group (n=13) – PV was ligated with prolene. The average values of portal pressure before PPVL in experimental animals were 7,50 ± 0,20 mmHg. All animals survived in the first group. 7 rats in the second group died on the 1-2 day after surgery because of PV thrombosis. There were no significant differences in the average values of portal pressure in the comparison groups after 15 days: the first group (n = 12) - 11,44 ± 0,06 mmHg, the second group (n = 6) - 11,24 ± 0,04 mm Hg. Despite the same type of portal hypertension model and its equal severity, the use of prolene thread caused a greater propensity to PV thrombosis.
| Published in | International Journal of Clinical and Experimental Medical Sciences (Volume 2, Issue 6) |
| DOI | 10.11648/j.ijcems.20160206.14 |
| Page(s) | 117-121 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Portal Hypertension, Partial Portal Vein Ligation, Prolene, Silk
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APA Style
Nikolay Olegovich Arefyev, Dmitry Victorovich Garbuzenko, Linar Rinatovich Khasanov. (2017). Choosing an Optimal Suture Material for Prehepatic Portal Hypertension Modeling. International Journal of Clinical and Experimental Medical Sciences, 2(6), 117-121. https://doi.org/10.11648/j.ijcems.20160206.14
ACS Style
Nikolay Olegovich Arefyev; Dmitry Victorovich Garbuzenko; Linar Rinatovich Khasanov. Choosing an Optimal Suture Material for Prehepatic Portal Hypertension Modeling. Int. J. Clin. Exp. Med. Sci. 2017, 2(6), 117-121. doi: 10.11648/j.ijcems.20160206.14
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Download@article{10.11648/j.ijcems.20160206.14,
author = {Nikolay Olegovich Arefyev and Dmitry Victorovich Garbuzenko and Linar Rinatovich Khasanov},
title = {Choosing an Optimal Suture Material for Prehepatic Portal Hypertension Modeling},
journal = {International Journal of Clinical and Experimental Medical Sciences},
volume = {2},
number = {6},
pages = {117-121},
doi = {10.11648/j.ijcems.20160206.14},
url = {https://doi.org/10.11648/j.ijcems.20160206.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20160206.14},
abstract = {If the catheter size, the thickness of a thread, the place for ligation were determined for the partial portal vein ligation (PPVL), the question of the suture material remains open. The aim of the study was to determine the optimal suture material (silk or prolene) for PPVL. The experiment was performed on 25 male adult outbred rats. The PPVL was carried out using the catheter 20G with thread 4-0. Portal pressure was measured before and 15 days after ligation. The measurements were performed by the differential manometer Testo 510 (Germany), which was connected to the catheter 24G, located in the distal part of the superior mesenteric vein. The animals were divided into two groups: the first group (n=12) – portal vein (PV) was ligated with silk, and the second group (n=13) – PV was ligated with prolene. The average values of portal pressure before PPVL in experimental animals were 7,50 ± 0,20 mmHg. All animals survived in the first group. 7 rats in the second group died on the 1-2 day after surgery because of PV thrombosis. There were no significant differences in the average values of portal pressure in the comparison groups after 15 days: the first group (n = 12) - 11,44 ± 0,06 mmHg, the second group (n = 6) - 11,24 ± 0,04 mm Hg. Despite the same type of portal hypertension model and its equal severity, the use of prolene thread caused a greater propensity to PV thrombosis.},
year = {2017}
}
TY - JOUR T1 - Choosing an Optimal Suture Material for Prehepatic Portal Hypertension Modeling AU - Nikolay Olegovich Arefyev AU - Dmitry Victorovich Garbuzenko AU - Linar Rinatovich Khasanov Y1 - 2017/01/18 PY - 2017 N1 - https://doi.org/10.11648/j.ijcems.20160206.14 DO - 10.11648/j.ijcems.20160206.14 T2 - International Journal of Clinical and Experimental Medical Sciences JF - International Journal of Clinical and Experimental Medical Sciences JO - International Journal of Clinical and Experimental Medical Sciences SP - 117 EP - 121 PB - Science Publishing Group SN - 2469-8032 UR - https://doi.org/10.11648/j.ijcems.20160206.14 AB - If the catheter size, the thickness of a thread, the place for ligation were determined for the partial portal vein ligation (PPVL), the question of the suture material remains open. The aim of the study was to determine the optimal suture material (silk or prolene) for PPVL. The experiment was performed on 25 male adult outbred rats. The PPVL was carried out using the catheter 20G with thread 4-0. Portal pressure was measured before and 15 days after ligation. The measurements were performed by the differential manometer Testo 510 (Germany), which was connected to the catheter 24G, located in the distal part of the superior mesenteric vein. The animals were divided into two groups: the first group (n=12) – portal vein (PV) was ligated with silk, and the second group (n=13) – PV was ligated with prolene. The average values of portal pressure before PPVL in experimental animals were 7,50 ± 0,20 mmHg. All animals survived in the first group. 7 rats in the second group died on the 1-2 day after surgery because of PV thrombosis. There were no significant differences in the average values of portal pressure in the comparison groups after 15 days: the first group (n = 12) - 11,44 ± 0,06 mmHg, the second group (n = 6) - 11,24 ± 0,04 mm Hg. Despite the same type of portal hypertension model and its equal severity, the use of prolene thread caused a greater propensity to PV thrombosis. VL - 2 IS - 6 ER -
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