Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis

Nonyelum Obiechina; Atef Michael; Angela Nandi; Rachit Adlakha; Amy Davis; Alicia Barnes

doi:doi:10.11648/j.ijcems.20200605.11

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Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis

Nonyelum Obiechina, Atef Michael, Angela Nandi, Rachit Adlakha, Amy Davis, Alicia Barnes

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 6, Issue 5)

Received: 15 September 2020 Accepted: 24 September 2020 Published: 7 October 2020

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Abstract

Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.

Published in	International Journal of Clinical and Experimental Medical Sciences (Volume 6, Issue 5)
DOI	10.11648/j.ijcems.20200605.11
Page(s)	85-90
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Stroke, Osteoporosis, Sarcopenia, Fractures, Osteosarcopenia

References

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APA Style

Nonyelum Obiechina, Atef Michael, Angela Nandi, Rachit Adlakha, Amy Davis, et al. (2020). Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. International Journal of Clinical and Experimental Medical Sciences, 6(5), 85-90. https://doi.org/10.11648/j.ijcems.20200605.11

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ACS Style

Nonyelum Obiechina; Atef Michael; Angela Nandi; Rachit Adlakha; Amy Davis, et al. Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. Int. J. Clin. Exp. Med. Sci. 2020, 6(5), 85-90. doi: 10.11648/j.ijcems.20200605.11

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AMA Style

Nonyelum Obiechina, Atef Michael, Angela Nandi, Rachit Adlakha, Amy Davis, et al. Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. Int J Clin Exp Med Sci. 2020;6(5):85-90. doi: 10.11648/j.ijcems.20200605.11

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@article{10.11648/j.ijcems.20200605.11,
  author = {Nonyelum Obiechina and Atef Michael and Angela Nandi and Rachit Adlakha and Amy Davis and Alicia Barnes},
  title = {Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis},
  journal = {International Journal of Clinical and Experimental Medical Sciences},
  volume = {6},
  number = {5},
  pages = {85-90},
  doi = {10.11648/j.ijcems.20200605.11},
  url = {https://doi.org/10.11648/j.ijcems.20200605.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20200605.11},
  abstract = {Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.},
 year = {2020}
}

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TY  - JOUR
T1  - Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis
AU  - Nonyelum Obiechina
AU  - Atef Michael
AU  - Angela Nandi
AU  - Rachit Adlakha
AU  - Amy Davis
AU  - Alicia Barnes
Y1  - 2020/10/07
PY  - 2020
N1  - https://doi.org/10.11648/j.ijcems.20200605.11
DO  - 10.11648/j.ijcems.20200605.11
T2  - International Journal of Clinical and Experimental Medical Sciences
JF  - International Journal of Clinical and Experimental Medical Sciences
JO  - International Journal of Clinical and Experimental Medical Sciences
SP  - 85
EP  - 90
PB  - Science Publishing Group
SN  - 2469-8032
UR  - https://doi.org/10.11648/j.ijcems.20200605.11
AB  - Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.
VL  - 6
IS  - 5
ER  -

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Author Information

Nonyelum Obiechina

University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom
Atef Michael

Russel Hall Hospital, Dudley Group National Health Service Foundation Trust, Dudley, United Kingdom
Angela Nandi

University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom
Rachit Adlakha

Health Education England, Birmingham, United Kingdom
Amy Davis

Heart of England National Health Service Foundation Trust, Birmingham, United Kingdom
Alicia Barnes

University Hospitals of Derby and Burton National Health Service Foundation Trust, Queens Hospital, Burton-on-Trent, United Kingdom

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APA Style

Nonyelum Obiechina, Atef Michael, Angela Nandi, Rachit Adlakha, Amy Davis, et al. (2020). Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. International Journal of Clinical and Experimental Medical Sciences, 6(5), 85-90. https://doi.org/10.11648/j.ijcems.20200605.11

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ACS Style

Nonyelum Obiechina; Atef Michael; Angela Nandi; Rachit Adlakha; Amy Davis, et al. Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. Int. J. Clin. Exp. Med. Sci. 2020, 6(5), 85-90. doi: 10.11648/j.ijcems.20200605.11

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AMA Style

Nonyelum Obiechina, Atef Michael, Angela Nandi, Rachit Adlakha, Amy Davis, et al. Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis. Int J Clin Exp Med Sci. 2020;6(5):85-90. doi: 10.11648/j.ijcems.20200605.11

Copy | Download

@article{10.11648/j.ijcems.20200605.11,
  author = {Nonyelum Obiechina and Atef Michael and Angela Nandi and Rachit Adlakha and Amy Davis and Alicia Barnes},
  title = {Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis},
  journal = {International Journal of Clinical and Experimental Medical Sciences},
  volume = {6},
  number = {5},
  pages = {85-90},
  doi = {10.11648/j.ijcems.20200605.11},
  url = {https://doi.org/10.11648/j.ijcems.20200605.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20200605.11},
  abstract = {Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.},
 year = {2020}
}

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TY  - JOUR
T1  - Hip Fractures in Elderly Stroke Patients - The Role of Sarcopenia and Osteoporosis
AU  - Nonyelum Obiechina
AU  - Atef Michael
AU  - Angela Nandi
AU  - Rachit Adlakha
AU  - Amy Davis
AU  - Alicia Barnes
Y1  - 2020/10/07
PY  - 2020
N1  - https://doi.org/10.11648/j.ijcems.20200605.11
DO  - 10.11648/j.ijcems.20200605.11
T2  - International Journal of Clinical and Experimental Medical Sciences
JF  - International Journal of Clinical and Experimental Medical Sciences
JO  - International Journal of Clinical and Experimental Medical Sciences
SP  - 85
EP  - 90
PB  - Science Publishing Group
SN  - 2469-8032
UR  - https://doi.org/10.11648/j.ijcems.20200605.11
AB  - Both hip fractures and stroke are common in elderly patients and hip fractures are especially prevalent in elderly stroke patients. This literature review is an attempt to explore the evidence for strategies to reduce hip fractures in stroke patients, the role of sarcopenia and osteoporosis in causing them and current and potential management strategies. A narrative approach was adopted in reviewing the evidence available on hip fractures in stroke patients, with regard to their incidence and prevalence, the role of sarcopenia and osteoporosis in their genesis and the evidence available for hip fracture prevention in stroke patients. I also attempt to explore the potential role of targeting muscle and bone as one unit in future therapeutic strategies. Although there are encouraging results from clinical trials on therapeutic interventions to prevent hip fractures in stroke patients, larger, more robustly designed studies are needed to validate many of the findings. Some evidence exists that suggest that hip fractures risk can be reduced in stroke patients but the findings need validation in larger more robust trials. Moreover it is clear that sarcopenia and osteoporosis are implicated in hip fractures in stroke and non-stroke elderly patients. A consensus on the definition of sarcopenia would also aid clarification of findings from studies.
VL  - 6
IS  - 5
ER  -

Copy | Download