Background: In December 2019, the outbreak of infectious pneumonia caused by a novel strain of coronavirus was named 'SARS-CoV2', which appeared in Wuhan, China. The said virus is highly contagious and rapidly spread across the world. So far, there is no effective antiviral drug in clinic. Objective: To make clinicians standardize the usage of the antiviral therapies against COVID-19, worldwide. Method: According to the recommended diagnosis and treatment protocols and relevant literature reports, suggested therapeutics include α-interferon (nebulization), lopinavir/ritonavir, ribavirin (recommended in combination with α-interferon or lopinavir/ritonavir), chloroquine phosphate, and arbidol. Recommendations based on various perspectives, such as timing and duration of medication, usage and dosage, adverse reactions and corresponding monitoring indicators, interactions, combination of antiviral drugs, efficacy evaluation indicators and discharge criteria were listed. Result: Pharmacist and clinicians provides knowledge of drug therapeutics for antiviral therapy and pharmaceutical care of clinical COVID-19. Conclusion: Recommendations of rational use of antiviral drugs against SARS-CoV2 may provide a timely reference to frontline clinicians in their fight against COVID-19 pneumonia to improve the clinical cure rate.
| Published in | International Journal of Clinical and Experimental Medical Sciences (Volume 7, Issue 4) |
| DOI | 10.11648/j.ijcems.20210704.18 |
| Page(s) | 115-119 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
COVID-19, Antiviral Drugs, SARS-CoV2
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APA Style
Naiju Zhang, Tianping Chen, Kuihua Xu, Chuanmiao Liu, Shousong Zhao, et al. (2021). Rational Use of Antiviral Drugs Against SARS-CoV2. International Journal of Clinical and Experimental Medical Sciences, 7(4), 115-119. https://doi.org/10.11648/j.ijcems.20210704.18
ACS Style
Naiju Zhang; Tianping Chen; Kuihua Xu; Chuanmiao Liu; Shousong Zhao, et al. Rational Use of Antiviral Drugs Against SARS-CoV2. Int. J. Clin. Exp. Med. Sci. 2021, 7(4), 115-119. doi: 10.11648/j.ijcems.20210704.18
AMA Style
Naiju Zhang, Tianping Chen, Kuihua Xu, Chuanmiao Liu, Shousong Zhao, et al. Rational Use of Antiviral Drugs Against SARS-CoV2. Int J Clin Exp Med Sci. 2021;7(4):115-119. doi: 10.11648/j.ijcems.20210704.18
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Download@article{10.11648/j.ijcems.20210704.18,
author = {Naiju Zhang and Tianping Chen and Kuihua Xu and Chuanmiao Liu and Shousong Zhao and Wei Li},
title = {Rational Use of Antiviral Drugs Against SARS-CoV2},
journal = {International Journal of Clinical and Experimental Medical Sciences},
volume = {7},
number = {4},
pages = {115-119},
doi = {10.11648/j.ijcems.20210704.18},
url = {https://doi.org/10.11648/j.ijcems.20210704.18},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20210704.18},
abstract = {Background: In December 2019, the outbreak of infectious pneumonia caused by a novel strain of coronavirus was named 'SARS-CoV2', which appeared in Wuhan, China. The said virus is highly contagious and rapidly spread across the world. So far, there is no effective antiviral drug in clinic. Objective: To make clinicians standardize the usage of the antiviral therapies against COVID-19, worldwide. Method: According to the recommended diagnosis and treatment protocols and relevant literature reports, suggested therapeutics include α-interferon (nebulization), lopinavir/ritonavir, ribavirin (recommended in combination with α-interferon or lopinavir/ritonavir), chloroquine phosphate, and arbidol. Recommendations based on various perspectives, such as timing and duration of medication, usage and dosage, adverse reactions and corresponding monitoring indicators, interactions, combination of antiviral drugs, efficacy evaluation indicators and discharge criteria were listed. Result: Pharmacist and clinicians provides knowledge of drug therapeutics for antiviral therapy and pharmaceutical care of clinical COVID-19. Conclusion: Recommendations of rational use of antiviral drugs against SARS-CoV2 may provide a timely reference to frontline clinicians in their fight against COVID-19 pneumonia to improve the clinical cure rate.},
year = {2021}
}
TY - JOUR T1 - Rational Use of Antiviral Drugs Against SARS-CoV2 AU - Naiju Zhang AU - Tianping Chen AU - Kuihua Xu AU - Chuanmiao Liu AU - Shousong Zhao AU - Wei Li Y1 - 2021/08/13 PY - 2021 N1 - https://doi.org/10.11648/j.ijcems.20210704.18 DO - 10.11648/j.ijcems.20210704.18 T2 - International Journal of Clinical and Experimental Medical Sciences JF - International Journal of Clinical and Experimental Medical Sciences JO - International Journal of Clinical and Experimental Medical Sciences SP - 115 EP - 119 PB - Science Publishing Group SN - 2469-8032 UR - https://doi.org/10.11648/j.ijcems.20210704.18 AB - Background: In December 2019, the outbreak of infectious pneumonia caused by a novel strain of coronavirus was named 'SARS-CoV2', which appeared in Wuhan, China. The said virus is highly contagious and rapidly spread across the world. So far, there is no effective antiviral drug in clinic. Objective: To make clinicians standardize the usage of the antiviral therapies against COVID-19, worldwide. Method: According to the recommended diagnosis and treatment protocols and relevant literature reports, suggested therapeutics include α-interferon (nebulization), lopinavir/ritonavir, ribavirin (recommended in combination with α-interferon or lopinavir/ritonavir), chloroquine phosphate, and arbidol. Recommendations based on various perspectives, such as timing and duration of medication, usage and dosage, adverse reactions and corresponding monitoring indicators, interactions, combination of antiviral drugs, efficacy evaluation indicators and discharge criteria were listed. Result: Pharmacist and clinicians provides knowledge of drug therapeutics for antiviral therapy and pharmaceutical care of clinical COVID-19. Conclusion: Recommendations of rational use of antiviral drugs against SARS-CoV2 may provide a timely reference to frontline clinicians in their fight against COVID-19 pneumonia to improve the clinical cure rate. VL - 7 IS - 4 ER -
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