Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults

Mohammad Firoj Hossain; Mohammad Shahed-Morshed; Mohammed Fariduddin; Tahniyah Haq; Shahjada Selim; Muhammad Abul Hasanat; Mohammad Habibul Ghani; Anil Yadav; Ibrahim Faisal; Anil Kumar Shah

doi:doi:10.11648/j.ijde.20210601.15

Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults

Mohammad Firoj Hossain, Mohammad Shahed-Morshed, Mohammed Fariduddin, Tahniyah Haq, Shahjada Selim, Muhammad Abul Hasanat, Mohammad Habibul Ghani, Anil Yadav, Ibrahim Faisal, Anil Kumar Shah

Published in International Journal of Diabetes and Endocrinology (Volume 6, Issue 1)

Received: 5 January 2021 Accepted: 18 January 2021 Published: 28 January 2021

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Abstract

Background and aims: Although vitamin D deficiency (VDD) is inversely associated with glucose intolerance, very limited data are available in Bangladesh. Thus, the study aimed to determine vitamin D status of Bangladeshi adults based on the glucose intolerance status. Materials & Methods: This cross-sectional study was carried out among 70 newly detected DM, age-group & sex-matched 76 newly detected pre-diabetes and 74 healthy control with normal glucose tolerance (NGT) based on American Diabetes Association, 2018 criteria. Participants were included consecutively from the Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU) over a period of 1 year by convenient sampling to see serum 25(OH)D which was measured by high performance liquid chromatography (HPLC) method. Results: Vitamin D levels decreased with increasing degrees of glucose intolerance [NGT: 16.82±6.57; prediabetes: 15.54±8.58; T2DM: 11.01±6.03 ng/ml, p<0.001] but significantly lower in T2DM than other two groups [T2DM vs. prediabetes, p=0.001; T2DM vs. control, p<0.001; prediabetes vs. control, p=NS]. The highest frequency of vitamin D deficiency was among individuals with T2DM (64.3%) followed by NGT (29.7%) and prediabetes (28.9%) [p<0.001]. Only HbA₁c had predictive association with vitamin D deficiency [OR (95%CI)=2.061 (1.178, 3.608), p=0.011]. Only DM but not pre-diabetes had predictive association with vitamin D deficiency compared with NGT [DM: OR (95%CI)=4.255 (2.117, 8.552), p<0.001; prediabetes: OR (95%CI)=0.963 (0.477, 1.946), p=0.916]. Conclusion: Vitamin D level was lower and frequency of vitamin D deficiency was higher in patients with DM. Only HbA₁c and DM had predictive association with vitamin D deficiency.

Published in	International Journal of Diabetes and Endocrinology (Volume 6, Issue 1)
DOI	10.11648/j.ijde.20210601.15
Page(s)	24-30
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Vitamin D, Type 2 Diabetes, Prediabetes, Bangladeshi Adults

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APA Style

Mohammad Firoj Hossain, Mohammad Shahed-Morshed, Mohammed Fariduddin, Tahniyah Haq, Shahjada Selim, et al. (2021). Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults. International Journal of Diabetes and Endocrinology, 6(1), 24-30. https://doi.org/10.11648/j.ijde.20210601.15

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ACS Style

Mohammad Firoj Hossain; Mohammad Shahed-Morshed; Mohammed Fariduddin; Tahniyah Haq; Shahjada Selim, et al. Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults. Int. J. Diabetes Endocrinol. 2021, 6(1), 24-30. doi: 10.11648/j.ijde.20210601.15

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AMA Style

Mohammad Firoj Hossain, Mohammad Shahed-Morshed, Mohammed Fariduddin, Tahniyah Haq, Shahjada Selim, et al. Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults. Int J Diabetes Endocrinol. 2021;6(1):24-30. doi: 10.11648/j.ijde.20210601.15

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@article{10.11648/j.ijde.20210601.15,
  author = {Mohammad Firoj Hossain and Mohammad Shahed-Morshed and Mohammed Fariduddin and Tahniyah Haq and Shahjada Selim and Muhammad Abul Hasanat and Mohammad Habibul Ghani and Anil Yadav and Ibrahim Faisal and Anil Kumar Shah},
  title = {Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults},
  journal = {International Journal of Diabetes and Endocrinology},
  volume = {6},
  number = {1},
  pages = {24-30},
  doi = {10.11648/j.ijde.20210601.15},
  url = {https://doi.org/10.11648/j.ijde.20210601.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20210601.15},
  abstract = {Background and aims: Although vitamin D deficiency (VDD) is inversely associated with glucose intolerance, very limited data are available in Bangladesh. Thus, the study aimed to determine vitamin D status of Bangladeshi adults based on the glucose intolerance status. Materials & Methods: This cross-sectional study was carried out among 70 newly detected DM, age-group & sex-matched 76 newly detected pre-diabetes and 74 healthy control with normal glucose tolerance (NGT) based on American Diabetes Association, 2018 criteria. Participants were included consecutively from the Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU) over a period of 1 year by convenient sampling to see serum 25(OH)D which was measured by high performance liquid chromatography (HPLC) method. Results: Vitamin D levels decreased with increasing degrees of glucose intolerance [NGT: 16.82±6.57; prediabetes: 15.54±8.58; T2DM: 11.01±6.03 ng/ml, p1c had predictive association with vitamin D deficiency [OR (95%CI)=2.061 (1.178, 3.608), p=0.011]. Only DM but not pre-diabetes had predictive association with vitamin D deficiency compared with NGT [DM: OR (95%CI)=4.255 (2.117, 8.552), p1c and DM had predictive association with vitamin D deficiency.},
 year = {2021}
}

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TY  - JOUR
T1  - Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults
AU  - Mohammad Firoj Hossain
AU  - Mohammad Shahed-Morshed
AU  - Mohammed Fariduddin
AU  - Tahniyah Haq
AU  - Shahjada Selim
AU  - Muhammad Abul Hasanat
AU  - Mohammad Habibul Ghani
AU  - Anil Yadav
AU  - Ibrahim Faisal
AU  - Anil Kumar Shah
Y1  - 2021/01/28
PY  - 2021
N1  - https://doi.org/10.11648/j.ijde.20210601.15
DO  - 10.11648/j.ijde.20210601.15
T2  - International Journal of Diabetes and Endocrinology
JF  - International Journal of Diabetes and Endocrinology
JO  - International Journal of Diabetes and Endocrinology
SP  - 24
EP  - 30
PB  - Science Publishing Group
SN  - 2640-1371
UR  - https://doi.org/10.11648/j.ijde.20210601.15
AB  - Background and aims: Although vitamin D deficiency (VDD) is inversely associated with glucose intolerance, very limited data are available in Bangladesh. Thus, the study aimed to determine vitamin D status of Bangladeshi adults based on the glucose intolerance status. Materials & Methods: This cross-sectional study was carried out among 70 newly detected DM, age-group & sex-matched 76 newly detected pre-diabetes and 74 healthy control with normal glucose tolerance (NGT) based on American Diabetes Association, 2018 criteria. Participants were included consecutively from the Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU) over a period of 1 year by convenient sampling to see serum 25(OH)D which was measured by high performance liquid chromatography (HPLC) method. Results: Vitamin D levels decreased with increasing degrees of glucose intolerance [NGT: 16.82±6.57; prediabetes: 15.54±8.58; T2DM: 11.01±6.03 ng/ml, p1c had predictive association with vitamin D deficiency [OR (95%CI)=2.061 (1.178, 3.608), p=0.011]. Only DM but not pre-diabetes had predictive association with vitamin D deficiency compared with NGT [DM: OR (95%CI)=4.255 (2.117, 8.552), p1c and DM had predictive association with vitamin D deficiency.
VL  - 6
IS  - 1
ER  -

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Author Information

Mohammad Firoj Hossain

Department of Endocrinology, Mugda Medical College, Dhaka, Bangladesh
Mohammad Shahed-Morshed

Emergency Department, Kurmitola General Hospital, Dhaka, Bangladesh
Mohammed Fariduddin

Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Tahniyah Haq

Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Shahjada Selim

Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Muhammad Abul Hasanat

Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Mohammad Habibul Ghani

Department of Medicine, Jinjira 20 Bed Hospital, Keraniganj, Dhaka, Bangladesh
Anil Yadav

Department of Internal Medicine (Endocrinology Division), Birat Medical College Teaching Hospital, Biratnagar, Nepal
Ibrahim Faisal

Deprtment of Medicine, Indira Gandhi Memorial Hospital, Kanbaa Aisa Rani Higun, Male, Republic of Maldives
Anil Kumar Shah

Department of Medicine (Endocrinology Unit), Chitwan Medical College, Chitwan, Nepal

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APA Style

Mohammad Firoj Hossain, Mohammad Shahed-Morshed, Mohammed Fariduddin, Tahniyah Haq, Shahjada Selim, et al. (2021). Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults. International Journal of Diabetes and Endocrinology, 6(1), 24-30. https://doi.org/10.11648/j.ijde.20210601.15

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ACS Style

Mohammad Firoj Hossain; Mohammad Shahed-Morshed; Mohammed Fariduddin; Tahniyah Haq; Shahjada Selim, et al. Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults. Int. J. Diabetes Endocrinol. 2021, 6(1), 24-30. doi: 10.11648/j.ijde.20210601.15

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AMA Style

Mohammad Firoj Hossain, Mohammad Shahed-Morshed, Mohammed Fariduddin, Tahniyah Haq, Shahjada Selim, et al. Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults. Int J Diabetes Endocrinol. 2021;6(1):24-30. doi: 10.11648/j.ijde.20210601.15

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@article{10.11648/j.ijde.20210601.15,
  author = {Mohammad Firoj Hossain and Mohammad Shahed-Morshed and Mohammed Fariduddin and Tahniyah Haq and Shahjada Selim and Muhammad Abul Hasanat and Mohammad Habibul Ghani and Anil Yadav and Ibrahim Faisal and Anil Kumar Shah},
  title = {Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults},
  journal = {International Journal of Diabetes and Endocrinology},
  volume = {6},
  number = {1},
  pages = {24-30},
  doi = {10.11648/j.ijde.20210601.15},
  url = {https://doi.org/10.11648/j.ijde.20210601.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20210601.15},
  abstract = {Background and aims: Although vitamin D deficiency (VDD) is inversely associated with glucose intolerance, very limited data are available in Bangladesh. Thus, the study aimed to determine vitamin D status of Bangladeshi adults based on the glucose intolerance status. Materials & Methods: This cross-sectional study was carried out among 70 newly detected DM, age-group & sex-matched 76 newly detected pre-diabetes and 74 healthy control with normal glucose tolerance (NGT) based on American Diabetes Association, 2018 criteria. Participants were included consecutively from the Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU) over a period of 1 year by convenient sampling to see serum 25(OH)D which was measured by high performance liquid chromatography (HPLC) method. Results: Vitamin D levels decreased with increasing degrees of glucose intolerance [NGT: 16.82±6.57; prediabetes: 15.54±8.58; T2DM: 11.01±6.03 ng/ml, p1c had predictive association with vitamin D deficiency [OR (95%CI)=2.061 (1.178, 3.608), p=0.011]. Only DM but not pre-diabetes had predictive association with vitamin D deficiency compared with NGT [DM: OR (95%CI)=4.255 (2.117, 8.552), p1c and DM had predictive association with vitamin D deficiency.},
 year = {2021}
}

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TY  - JOUR
T1  - Vitamin D Status in Different Categories of Glucose Intolerance in Bangladeshi Adults
AU  - Mohammad Firoj Hossain
AU  - Mohammad Shahed-Morshed
AU  - Mohammed Fariduddin
AU  - Tahniyah Haq
AU  - Shahjada Selim
AU  - Muhammad Abul Hasanat
AU  - Mohammad Habibul Ghani
AU  - Anil Yadav
AU  - Ibrahim Faisal
AU  - Anil Kumar Shah
Y1  - 2021/01/28
PY  - 2021
N1  - https://doi.org/10.11648/j.ijde.20210601.15
DO  - 10.11648/j.ijde.20210601.15
T2  - International Journal of Diabetes and Endocrinology
JF  - International Journal of Diabetes and Endocrinology
JO  - International Journal of Diabetes and Endocrinology
SP  - 24
EP  - 30
PB  - Science Publishing Group
SN  - 2640-1371
UR  - https://doi.org/10.11648/j.ijde.20210601.15
AB  - Background and aims: Although vitamin D deficiency (VDD) is inversely associated with glucose intolerance, very limited data are available in Bangladesh. Thus, the study aimed to determine vitamin D status of Bangladeshi adults based on the glucose intolerance status. Materials & Methods: This cross-sectional study was carried out among 70 newly detected DM, age-group & sex-matched 76 newly detected pre-diabetes and 74 healthy control with normal glucose tolerance (NGT) based on American Diabetes Association, 2018 criteria. Participants were included consecutively from the Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU) over a period of 1 year by convenient sampling to see serum 25(OH)D which was measured by high performance liquid chromatography (HPLC) method. Results: Vitamin D levels decreased with increasing degrees of glucose intolerance [NGT: 16.82±6.57; prediabetes: 15.54±8.58; T2DM: 11.01±6.03 ng/ml, p1c had predictive association with vitamin D deficiency [OR (95%CI)=2.061 (1.178, 3.608), p=0.011]. Only DM but not pre-diabetes had predictive association with vitamin D deficiency compared with NGT [DM: OR (95%CI)=4.255 (2.117, 8.552), p1c and DM had predictive association with vitamin D deficiency.
VL  - 6
IS  - 1
ER  -

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