Background: Diabetes mellitus is a chronic disease caused by endocrine metabolic disorders, which has developed into a global public health problem. Currently, the number of people with diabetes has reached approximately 425 million worldwide. It is estimated that the prevalence of diabetes will increase by 48% by 2045. Genistein, a naturally occurring phytoestrogen found mainly in soybeans, is of great importance in the prevention of many diseases, including tumors and cardiovascular disease. Previous studies have shown that dietary supplementation with phytoestrogens can prevent atherosclerosis. Objective: To describe the mechanism and current status of the effect of genistein on diabetic cardiovascular complications, with the aim of improving the prognosis of patients with diabetic combined cardiovascular complications. Methods: To show the specific value of genistein in diabetic cardiovascular complications by elaborating the biochemical properties of genistein and using the interaction of genistein with vascular endothelium, platelet aggregation, lipid deposition, and inflammation as a starting point. Conclusion: The biological properties and mechanism of action of genistein can provide more references for the prevention and treatment of cardiovascular complications in clinical work.
| Published in | International Journal of Diabetes and Endocrinology (Volume 7, Issue 3) |
| DOI | 10.11648/j.ijde.20220703.11 |
| Page(s) | 50-53 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Genistein, Diabetes, Cardiovascular, Mechanism
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APA Style
Na Li, Guomin Yang, Ying Pan, Yu Zhao. (2022). Effect of Genistein on Diabetic Cardiovascular Complications. International Journal of Diabetes and Endocrinology, 7(3), 50-53. https://doi.org/10.11648/j.ijde.20220703.11
ACS Style
Na Li; Guomin Yang; Ying Pan; Yu Zhao. Effect of Genistein on Diabetic Cardiovascular Complications. Int. J. Diabetes Endocrinol. 2022, 7(3), 50-53. doi: 10.11648/j.ijde.20220703.11
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Download@article{10.11648/j.ijde.20220703.11,
author = {Na Li and Guomin Yang and Ying Pan and Yu Zhao},
title = {Effect of Genistein on Diabetic Cardiovascular Complications},
journal = {International Journal of Diabetes and Endocrinology},
volume = {7},
number = {3},
pages = {50-53},
doi = {10.11648/j.ijde.20220703.11},
url = {https://doi.org/10.11648/j.ijde.20220703.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20220703.11},
abstract = {Background: Diabetes mellitus is a chronic disease caused by endocrine metabolic disorders, which has developed into a global public health problem. Currently, the number of people with diabetes has reached approximately 425 million worldwide. It is estimated that the prevalence of diabetes will increase by 48% by 2045. Genistein, a naturally occurring phytoestrogen found mainly in soybeans, is of great importance in the prevention of many diseases, including tumors and cardiovascular disease. Previous studies have shown that dietary supplementation with phytoestrogens can prevent atherosclerosis. Objective: To describe the mechanism and current status of the effect of genistein on diabetic cardiovascular complications, with the aim of improving the prognosis of patients with diabetic combined cardiovascular complications. Methods: To show the specific value of genistein in diabetic cardiovascular complications by elaborating the biochemical properties of genistein and using the interaction of genistein with vascular endothelium, platelet aggregation, lipid deposition, and inflammation as a starting point. Conclusion: The biological properties and mechanism of action of genistein can provide more references for the prevention and treatment of cardiovascular complications in clinical work.},
year = {2022}
}
TY - JOUR T1 - Effect of Genistein on Diabetic Cardiovascular Complications AU - Na Li AU - Guomin Yang AU - Ying Pan AU - Yu Zhao Y1 - 2022/07/28 PY - 2022 N1 - https://doi.org/10.11648/j.ijde.20220703.11 DO - 10.11648/j.ijde.20220703.11 T2 - International Journal of Diabetes and Endocrinology JF - International Journal of Diabetes and Endocrinology JO - International Journal of Diabetes and Endocrinology SP - 50 EP - 53 PB - Science Publishing Group SN - 2640-1371 UR - https://doi.org/10.11648/j.ijde.20220703.11 AB - Background: Diabetes mellitus is a chronic disease caused by endocrine metabolic disorders, which has developed into a global public health problem. Currently, the number of people with diabetes has reached approximately 425 million worldwide. It is estimated that the prevalence of diabetes will increase by 48% by 2045. Genistein, a naturally occurring phytoestrogen found mainly in soybeans, is of great importance in the prevention of many diseases, including tumors and cardiovascular disease. Previous studies have shown that dietary supplementation with phytoestrogens can prevent atherosclerosis. Objective: To describe the mechanism and current status of the effect of genistein on diabetic cardiovascular complications, with the aim of improving the prognosis of patients with diabetic combined cardiovascular complications. Methods: To show the specific value of genistein in diabetic cardiovascular complications by elaborating the biochemical properties of genistein and using the interaction of genistein with vascular endothelium, platelet aggregation, lipid deposition, and inflammation as a starting point. Conclusion: The biological properties and mechanism of action of genistein can provide more references for the prevention and treatment of cardiovascular complications in clinical work. VL - 7 IS - 3 ER -
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