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Ficus Sycomorus L. Extracts: Phytochemical Screening, Total Polyphenols and Flavonoids Contents, Antioxidant and Antibacterial Activity

Received: 10 August 2022    Accepted: 25 August 2022    Published: 31 August 2022
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Abstract

Ficus Sycomorus L. is a plant widely used in Senegal by traditional healers for the management of certain pathologies such as stomach aches or skin rashes. The objective of our work is to determine the contents of total polyphenols and flavonoids of the methanolic extracts of the different organs of Ficus Sycomorus L. Subsequently, the antioxidant and antimicrobial activities of these extracts were studied. Polyphenols, flavonoids, sterols and polyterpenes are present in all plant organs. The antioxidant capacities expressed as IC50 of the methanolic extracts of the different organs of Ficus Sycomorus L. reveal that the stem bark extract has the best activity with an IC50 of 0.237 ± 0.016 mg/mL. This good activity is in agreement with the high levels of total polyphenols in stem bark (193.4257 ± 0.6971 mg/g of gallic acid equivalent). The steam bark extract give the best results for the antimicrobial tests with a MIC value of 1.875 mg/mL on Staphylococcus Aureus ATCC 29212. The good scavenging activity of the Ficus Sycomorus L. extracts on free radical and the good biological activity justify the use of this plant in traditional medicine. The best antibacterial activities of stem bark of Ficus Sycomorus L. on the different bacterial strains can be explained by the higher polyphenol content of stem bark compared to leaves and fruits of Ficus Sycomorus L.

Published in Science Journal of Chemistry (Volume 10, Issue 4)
DOI 10.11648/j.sjc.20221004.15
Page(s) 126-132
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ficus Sycomorus L., Polyphenols, Flavonoids, Antioxidant Activity, Antimicrobial Activity

References
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    Abba Diarra Kone, Bedie Mbow, Aissatou Alioune Gaye, Samba Fama Ndoye, Mohamed Gaye. (2022). Ficus Sycomorus L. Extracts: Phytochemical Screening, Total Polyphenols and Flavonoids Contents, Antioxidant and Antibacterial Activity. Science Journal of Chemistry, 10(4), 126-132. https://doi.org/10.11648/j.sjc.20221004.15

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    Abba Diarra Kone; Bedie Mbow; Aissatou Alioune Gaye; Samba Fama Ndoye; Mohamed Gaye. Ficus Sycomorus L. Extracts: Phytochemical Screening, Total Polyphenols and Flavonoids Contents, Antioxidant and Antibacterial Activity. Sci. J. Chem. 2022, 10(4), 126-132. doi: 10.11648/j.sjc.20221004.15

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    AMA Style

    Abba Diarra Kone, Bedie Mbow, Aissatou Alioune Gaye, Samba Fama Ndoye, Mohamed Gaye. Ficus Sycomorus L. Extracts: Phytochemical Screening, Total Polyphenols and Flavonoids Contents, Antioxidant and Antibacterial Activity. Sci J Chem. 2022;10(4):126-132. doi: 10.11648/j.sjc.20221004.15

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  • @article{10.11648/j.sjc.20221004.15,
      author = {Abba Diarra Kone and Bedie Mbow and Aissatou Alioune Gaye and Samba Fama Ndoye and Mohamed Gaye},
      title = {Ficus Sycomorus L. Extracts: Phytochemical Screening, Total Polyphenols and Flavonoids Contents, Antioxidant and Antibacterial Activity},
      journal = {Science Journal of Chemistry},
      volume = {10},
      number = {4},
      pages = {126-132},
      doi = {10.11648/j.sjc.20221004.15},
      url = {https://doi.org/10.11648/j.sjc.20221004.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20221004.15},
      abstract = {Ficus Sycomorus L. is a plant widely used in Senegal by traditional healers for the management of certain pathologies such as stomach aches or skin rashes. The objective of our work is to determine the contents of total polyphenols and flavonoids of the methanolic extracts of the different organs of Ficus Sycomorus L. Subsequently, the antioxidant and antimicrobial activities of these extracts were studied. Polyphenols, flavonoids, sterols and polyterpenes are present in all plant organs. The antioxidant capacities expressed as IC50 of the methanolic extracts of the different organs of Ficus Sycomorus L. reveal that the stem bark extract has the best activity with an IC50 of 0.237 ± 0.016 mg/mL. This good activity is in agreement with the high levels of total polyphenols in stem bark (193.4257 ± 0.6971 mg/g of gallic acid equivalent). The steam bark extract give the best results for the antimicrobial tests with a MIC value of 1.875 mg/mL on Staphylococcus Aureus ATCC 29212. The good scavenging activity of the Ficus Sycomorus L. extracts on free radical and the good biological activity justify the use of this plant in traditional medicine. The best antibacterial activities of stem bark of Ficus Sycomorus L. on the different bacterial strains can be explained by the higher polyphenol content of stem bark compared to leaves and fruits of Ficus Sycomorus L.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Ficus Sycomorus L. Extracts: Phytochemical Screening, Total Polyphenols and Flavonoids Contents, Antioxidant and Antibacterial Activity
    AU  - Abba Diarra Kone
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    AU  - Aissatou Alioune Gaye
    AU  - Samba Fama Ndoye
    AU  - Mohamed Gaye
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    DO  - 10.11648/j.sjc.20221004.15
    T2  - Science Journal of Chemistry
    JF  - Science Journal of Chemistry
    JO  - Science Journal of Chemistry
    SP  - 126
    EP  - 132
    PB  - Science Publishing Group
    SN  - 2330-099X
    UR  - https://doi.org/10.11648/j.sjc.20221004.15
    AB  - Ficus Sycomorus L. is a plant widely used in Senegal by traditional healers for the management of certain pathologies such as stomach aches or skin rashes. The objective of our work is to determine the contents of total polyphenols and flavonoids of the methanolic extracts of the different organs of Ficus Sycomorus L. Subsequently, the antioxidant and antimicrobial activities of these extracts were studied. Polyphenols, flavonoids, sterols and polyterpenes are present in all plant organs. The antioxidant capacities expressed as IC50 of the methanolic extracts of the different organs of Ficus Sycomorus L. reveal that the stem bark extract has the best activity with an IC50 of 0.237 ± 0.016 mg/mL. This good activity is in agreement with the high levels of total polyphenols in stem bark (193.4257 ± 0.6971 mg/g of gallic acid equivalent). The steam bark extract give the best results for the antimicrobial tests with a MIC value of 1.875 mg/mL on Staphylococcus Aureus ATCC 29212. The good scavenging activity of the Ficus Sycomorus L. extracts on free radical and the good biological activity justify the use of this plant in traditional medicine. The best antibacterial activities of stem bark of Ficus Sycomorus L. on the different bacterial strains can be explained by the higher polyphenol content of stem bark compared to leaves and fruits of Ficus Sycomorus L.
    VL  - 10
    IS  - 4
    ER  - 

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Author Information
  • Department of Chemistry, University Cheikh Anta DIOP, Dakar, SenegalDepartment of Chemistry, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Chemistry, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Chemistry, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Chemistry, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Chemistry, University Cheikh Anta Diop, Dakar, Senegal

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