Volume 10, Issue 3, September 2025

  • Research Article

    Norcantharidin Inhibits an Angiogenesis of Croquel-180 Sarcomatous Cells

    Hong-Chol Ri, Dong-Min Han, Kwang-Il To*, Yong Il Yun, Song-Nam Go, Chang-Guk Kim, Su-Chol Rim

    Issue: Volume 10, Issue 3, September 2025
    Pages: 37-44
    Received: 11 May 2025
    Accepted: 11 June 2025
    Published: 10 July 2025
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    Abstract: Norcantharidin (NCTD) is a demethylated water-soluble synthetic small molecule of cantharidin (CTD), has been reported that it has anticancer activities including apoptosis and anti-angiogenesis. NCTD reduced VEGF production and the expression of integrin-β1 in tumor cells even at the low concentrations with less toxicity to the kidney or liver, an... Show More
  • Research Article

    Analysis of the Vitamin D Receptor (VDR) Start Codon Polymorphism (Rs2228570) in Hemodialysis Patients from Abidjan, Côte d’Ivoire

    Koné-Dakouri Yékayo Bénédicte*, Yao-Yapo Carine Mireille, Kouacou Kadio Morel, Koné-Koné Fatoumata, Kouamé-Dia Yah Chantal, Yayo Sagou Eric, Kacou-N’Douba Adèle, Hauhouot-Attoungbre Marie Laure

    Issue: Volume 10, Issue 3, September 2025
    Pages: 45-51
    Received: 2 July 2025
    Accepted: 14 July 2025
    Published: 30 July 2025
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    Abstract: In patients with chronic kidney disease (CKD), particularly those undergoing hemodialysis, vitamin D deficiency is highly prevalent. Individual sensitivity to vitamin D can be influenced by genetic variations in the vitamin D receptor (VDR) gene. Among these, the rs2228570 polymorphism, located in exon 2 and commonly referred to as the FokI polymor... Show More
  • Research Article

    Multidrug Resistance of Escherichia Coli by Production of TOHO, NDM and SHV Type Enzymes at the Pietro Annigoni Research Centre (CERBA)

    Rhaina Olivia Badini*, Amana Mètuor Dabiré, Rabiétou Nikiéma, Bambara Eliada Lionel, Abdoul Karim Ouattara, Théodora Mahoukèdè Zohoncon, Jacques Simporé

    Issue: Volume 10, Issue 3, September 2025
    Pages: 52-60
    Received: 10 August 2025
    Accepted: 20 August 2025
    Published: 23 September 2025
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    Abstract: Antibiotics are drugs used to fight infections caused by bacteria. They are one of the most important discoveries in medicine that has saved and continues to save millions of lives each year, but their effectiveness is threatened because bacteria can adapt and resist treatment. The present study aimed to identify the bla NDM, bla SHV and bla TOHO g... Show More