Biochemistry and Molecular Biology

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Volume 10, Issue 3, September 2025

  • Research Article

    Norcantharidin Inhibits an Angiogenesis of Croquel-180 Sarcomatous Cells

    Hong-Chol Ri, Dong-Min Han, Kwang-Il To*, Yong Il Yun, Song-Nam Go, Chang-Guk Kim, Su-Chol Rim

    Issue: Volume 10, Issue 3, September 2025
    Pages: 37-44
    Received: 11 May 2025
    Accepted: 11 June 2025
    Published: 10 July 2025
    DOI: 10.11648/j.bmb.20251003.11
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    Abstract: Norcantharidin (NCTD) is a demethylated water-soluble synthetic small molecule of cantharidin (CTD), has been reported that it has anticancer activities including apoptosis and anti-angiogenesis. NCTD reduced VEGF production and the expression of integrin-β1 in tumor cells even at the low concentrations with less toxicity to the kidney or liver, an... Show More
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