Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah

Walaa Mohammedsaeed; Amal M. Surrati; Hadiah Q. Alnakhli; Malak Alharbi; Nidda Syeed

doi:doi:10.11648/j.ijde.20200504.12

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Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah

Walaa Mohammedsaeed, Amal M. Surrati, Hadiah Q. Alnakhli, Malak Alharbi, Nidda Syeed

Published in International Journal of Diabetes and Endocrinology (Volume 5, Issue 4)

Received: 12 November 2020 Accepted: 27 November 2020 Published: 4 December 2020

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Abstract

It is an essential to evaluate the potential biomarkers affecting the progression of disease in COVID-19 patients. Therefore, we investigated the relationship between Ferritin levels and hematological parameters and severity of COVID-19 to explore its role in predicting the severity of COVID-19. This retrospective study was conducted in different Hospitals at Madinah region, Saudi Arabia. In the present study, a total of 112 cases of COVID-19 patients. The patient records included the clinical and laboratory data that was used for analysis by using the GraphPad Prism Software. Data presented as mean (SD), all differences were statistically significant at the level of P≤0.05 or ≤0.001. There were significantly increased levels of ferritin, neutrophil and leukocyte counts in severe COVID-19 cases (1857 (50.9), 9.9 (2.8), 9.9 (2.8) respectively) compared with non-sever cases. Additionally, there were significantly reduction in lymphocytes counts in COVID-19 patients (1.3 (9.5), P=0.001). There were also strong correlations between elevation of ferritin levels or reduction of lymphocytes and the severity COVID-19 infection (r=0.53, OR: 5.88 and r=-0.55, OR: 3.98 respectively). The results demonstrate that high values for neutrophil, leukocyte counts and Ferritin levels, and low values for lymphocyte counts may have diagnostic properties concerning COVID-19 in severe cases.

Published in	International Journal of Diabetes and Endocrinology (Volume 5, Issue 4)
DOI	10.11648/j.ijde.20200504.12
Page(s)	61-66
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Neutrophil, Leukocyte, Ferritin, Lymphocyte, COVID-19

References

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APA Style

Walaa Mohammedsaeed, Amal M. Surrati, Hadiah Q. Alnakhli, Malak Alharbi, Nidda Syeed. (2020). Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah. International Journal of Diabetes and Endocrinology, 5(4), 61-66. https://doi.org/10.11648/j.ijde.20200504.12

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ACS Style

Walaa Mohammedsaeed; Amal M. Surrati; Hadiah Q. Alnakhli; Malak Alharbi; Nidda Syeed. Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah. Int. J. Diabetes Endocrinol. 2020, 5(4), 61-66. doi: 10.11648/j.ijde.20200504.12

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AMA Style

Walaa Mohammedsaeed, Amal M. Surrati, Hadiah Q. Alnakhli, Malak Alharbi, Nidda Syeed. Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah. Int J Diabetes Endocrinol. 2020;5(4):61-66. doi: 10.11648/j.ijde.20200504.12

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@article{10.11648/j.ijde.20200504.12,
  author = {Walaa Mohammedsaeed and Amal M. Surrati and Hadiah Q. Alnakhli and Malak Alharbi and Nidda Syeed},
  title = {Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah},
  journal = {International Journal of Diabetes and Endocrinology},
  volume = {5},
  number = {4},
  pages = {61-66},
  doi = {10.11648/j.ijde.20200504.12},
  url = {https://doi.org/10.11648/j.ijde.20200504.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20200504.12},
  abstract = {It is an essential to evaluate the potential biomarkers affecting the progression of disease in COVID-19 patients. Therefore, we investigated the relationship between Ferritin levels and hematological parameters and severity of COVID-19 to explore its role in predicting the severity of COVID-19. This retrospective study was conducted in different Hospitals at Madinah region, Saudi Arabia. In the present study, a total of 112 cases of COVID-19 patients. The patient records included the clinical and laboratory data that was used for analysis by using the GraphPad Prism Software. Data presented as mean (SD), all differences were statistically significant at the level of P≤0.05 or ≤0.001. There were significantly increased levels of ferritin, neutrophil and leukocyte counts in severe COVID-19 cases (1857 (50.9), 9.9 (2.8), 9.9 (2.8) respectively) compared with non-sever cases. Additionally, there were significantly reduction in lymphocytes counts in COVID-19 patients (1.3 (9.5), P=0.001). There were also strong correlations between elevation of ferritin levels or reduction of lymphocytes and the severity COVID-19 infection (r=0.53, OR: 5.88 and r=-0.55, OR: 3.98 respectively). The results demonstrate that high values for neutrophil, leukocyte counts and Ferritin levels, and low values for lymphocyte counts may have diagnostic properties concerning COVID-19 in severe cases.},
 year = {2020}
}

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TY - JOUR
T1 - Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah
AU - Walaa Mohammedsaeed
AU - Amal M. Surrati
AU - Hadiah Q. Alnakhli
AU - Malak Alharbi
AU - Nidda Syeed
Y1 - 2020/12/04
PY - 2020
N1 - https://doi.org/10.11648/j.ijde.20200504.12
DO - 10.11648/j.ijde.20200504.12
T2 - International Journal of Diabetes and Endocrinology
JF - International Journal of Diabetes and Endocrinology
JO - International Journal of Diabetes and Endocrinology
SP - 61
EP - 66
PB - Science Publishing Group
SN - 2640-1371
UR - https://doi.org/10.11648/j.ijde.20200504.12
AB - It is an essential to evaluate the potential biomarkers affecting the progression of disease in COVID-19 patients. Therefore, we investigated the relationship between Ferritin levels and hematological parameters and severity of COVID-19 to explore its role in predicting the severity of COVID-19. This retrospective study was conducted in different Hospitals at Madinah region, Saudi Arabia. In the present study, a total of 112 cases of COVID-19 patients. The patient records included the clinical and laboratory data that was used for analysis by using the GraphPad Prism Software. Data presented as mean (SD), all differences were statistically significant at the level of P≤0.05 or ≤0.001. There were significantly increased levels of ferritin, neutrophil and leukocyte counts in severe COVID-19 cases (1857 (50.9), 9.9 (2.8), 9.9 (2.8) respectively) compared with non-sever cases. Additionally, there were significantly reduction in lymphocytes counts in COVID-19 patients (1.3 (9.5), P=0.001). There were also strong correlations between elevation of ferritin levels or reduction of lymphocytes and the severity COVID-19 infection (r=0.53, OR: 5.88 and r=-0.55, OR: 3.98 respectively). The results demonstrate that high values for neutrophil, leukocyte counts and Ferritin levels, and low values for lymphocyte counts may have diagnostic properties concerning COVID-19 in severe cases.
VL - 5
IS - 4
ER -

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Author Information

Walaa Mohammedsaeed

Medical Laboratory Science, College of Applied Medical Sciences, Taibah University, Madinah, Saudi Arabia
Amal M. Surrati

Family and Community Medicine, College of Medicine, Taibah University, Madinah, Saudi Arabia
Hadiah Q. Alnakhli

Department of Internal Medicine, Ohud Hospital, Madinah, Saudi Arabia
Malak Alharbi

Department of Internal Medicine, Madinah General Hospital, Madinah, Saudi Arabia
Nidda Syeed

Medical Laboratory Science, College of Applied Medical Sciences, Taibah University, Madinah, Saudi Arabia

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APA Style

Walaa Mohammedsaeed, Amal M. Surrati, Hadiah Q. Alnakhli, Malak Alharbi, Nidda Syeed. (2020). Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah. International Journal of Diabetes and Endocrinology, 5(4), 61-66. https://doi.org/10.11648/j.ijde.20200504.12

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ACS Style

Walaa Mohammedsaeed; Amal M. Surrati; Hadiah Q. Alnakhli; Malak Alharbi; Nidda Syeed. Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah. Int. J. Diabetes Endocrinol. 2020, 5(4), 61-66. doi: 10.11648/j.ijde.20200504.12

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AMA Style

Walaa Mohammedsaeed, Amal M. Surrati, Hadiah Q. Alnakhli, Malak Alharbi, Nidda Syeed. Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah. Int J Diabetes Endocrinol. 2020;5(4):61-66. doi: 10.11648/j.ijde.20200504.12

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@article{10.11648/j.ijde.20200504.12,
  author = {Walaa Mohammedsaeed and Amal M. Surrati and Hadiah Q. Alnakhli and Malak Alharbi and Nidda Syeed},
  title = {Alteration of Ferritin Levels and Lymphocytes Counts in Saudi Patients with COVID-19 Infection in Al Madinah Al Munawarah},
  journal = {International Journal of Diabetes and Endocrinology},
  volume = {5},
  number = {4},
  pages = {61-66},
  doi = {10.11648/j.ijde.20200504.12},
  url = {https://doi.org/10.11648/j.ijde.20200504.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20200504.12},
  abstract = {It is an essential to evaluate the potential biomarkers affecting the progression of disease in COVID-19 patients. Therefore, we investigated the relationship between Ferritin levels and hematological parameters and severity of COVID-19 to explore its role in predicting the severity of COVID-19. This retrospective study was conducted in different Hospitals at Madinah region, Saudi Arabia. In the present study, a total of 112 cases of COVID-19 patients. The patient records included the clinical and laboratory data that was used for analysis by using the GraphPad Prism Software. Data presented as mean (SD), all differences were statistically significant at the level of P≤0.05 or ≤0.001. There were significantly increased levels of ferritin, neutrophil and leukocyte counts in severe COVID-19 cases (1857 (50.9), 9.9 (2.8), 9.9 (2.8) respectively) compared with non-sever cases. Additionally, there were significantly reduction in lymphocytes counts in COVID-19 patients (1.3 (9.5), P=0.001). There were also strong correlations between elevation of ferritin levels or reduction of lymphocytes and the severity COVID-19 infection (r=0.53, OR: 5.88 and r=-0.55, OR: 3.98 respectively). The results demonstrate that high values for neutrophil, leukocyte counts and Ferritin levels, and low values for lymphocyte counts may have diagnostic properties concerning COVID-19 in severe cases.},
 year = {2020}
}

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