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The Effect of Aspirin on HbA1c Assay Among Diabetic Hypertensive Patients Attending Abu Aqulah Centre in Wad Madani, Gezira State, Sudan
Abdalwahab Ahmed Abdalla,
Salman Taha Ahmed Elmukashfi,
Ahmed Yasin Hassan,
Ameer Dafalla,
Khalid Abdelsamea
Issue:
Volume 8, Issue 1, March 2023
Pages:
1-5
Received:
4 October 2022
Accepted:
26 October 2022
Published:
9 January 2023
Abstract: Background and Objective: Diabetes is one of the most common diseases in the world, and its prevalence has increased dramatically in the last century until it reached approximately 422 million in the world. The increase in disease has lead to a decrease in production and an increase in financial costs for patients, several methods were taken to diagnose diabetes millets such as glucose tolerance and fasting glucose measurement until the Ministry of World Health approved in 2011 that hemoglobin A1c is suitable for diagnosing and controlling diabetes. But some studies indicated Hemoglobin A1c is affected by aspirin and other factors that can give false results and affect diagnosis or monitoring. So this Cross-Sectional study was conducted and the aim to study the effect of aspirin on hemoglobin A1c among diabetic hypertensive, to determine the effect of aspirin, age, sex and fasting glucose on HbA1c concentration. Materials and Methods: ichroma was used for measuring HbA1c and colorimeter for measuring fasting blood glucose. Questionnaire for age and sex, the venous sample were collected in (EDTA) Ethlyine Di amin tetra acetic acid for HbA1c measuring and fluoride oxalate for fasting measuring. The study was done at Wad Madni and included 100 patients with diabetes and hypertension, 50 of them used aspirin, while the other 50 did not use aspirin. Results: The result of the study was increased in HbA1c in patient use aspirin more than 2 years HbA1c mean was (9.7) and less in patient use aspirin less than 2 years HbA1c mean (9.4), p value (0.048). The comparison between male and female the HbA1c was more in female (10.6) than male (9.2), p value (0.045) also HbA1c associated with BMI and fasting glucose. The statistically package for social studies (SPSS) version 20 programs was used for the analysis of data. Relative risk and odd ratio also should be calculated was used for statistical analysis. Conclusion: The level of HbA1c is increase with aspirin using and associated with fasting blood glucose and BMI. And female have high level of HbA1c than male. The age of patient not effect on HbA1c level.
Abstract: Background and Objective: Diabetes is one of the most common diseases in the world, and its prevalence has increased dramatically in the last century until it reached approximately 422 million in the world. The increase in disease has lead to a decrease in production and an increase in financial costs for patients, several methods were taken to dia...
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Biothesiometric Assessment of Persons Living with Diabetes Mellitus in a Tertiary Hospital in Uyo, Southern Nigeria
Onung Samuel,
Akhimienho Kingsley,
Amadi Collins,
Anyiekere Ekanem,
Umoren Ubong,
Ekuma Ikwo,
Asukpong Eso
Issue:
Volume 8, Issue 1, March 2023
Pages:
6-11
Received:
10 January 2023
Accepted:
2 February 2023
Published:
16 February 2023
Abstract: Background: The burden of foot ulceration and amputation among persons living with diabetes mellitus is quite huge and peripheral neuropathy is a well known risk factor for this. The prevalence of peripheral neuropathy and associated factors among persons living with diabetes, using an objective assessment (biothesiometer), is unknown in our study environment. Method: This was a cross-sectional study involving 108 age matched diabetes mellitus patients and controls. The study was conducted in the Diabetes Clinic of the University of Uyo Teaching Hospital, in Southern Nigeria. Basic demographics and other parameters such as duration of diabetes and glycated haemoglobin were recorded. All participants were recruited consecutively and screened for vibration perception threshold (VPT) using a biothesiometer. Participants with VPT ≥ 25 were considered to have significant neuropathy. Results: Significant neuropathy was recorded in 18 (33.3%) of the 54 diabetes patients. Only 3 (5.5%) of the 54 controls had significant neuropathy (p<0.01). The diabetes patients with significant neuropathy had a mean HbA1c of 8.9% compared to 7.3% for diabetes patients without significant neuropathy (p=0.02). The mean age of the diabetes patients with peripheral neuropathy was 54.0±2.3 years compared to 48.3±1.9 years for the diabetes patients without peripheral neuropathy (p<0.01). The mean duration of diabetes among diabetes patients with significant neuropathy was 10.3 years compared to 6.7 years for diabetes patients without significant neuropathy (p=0.01). Conclusion: There is a high prevalence of significant peripheral neuropathy among diabetes patients as determined using a biothesiometer. Early detection and achieving a good glycaemic control may help in reducing this burden which exposes the patients to the risk of possible amputation, depression and even death.
Abstract: Background: The burden of foot ulceration and amputation among persons living with diabetes mellitus is quite huge and peripheral neuropathy is a well known risk factor for this. The prevalence of peripheral neuropathy and associated factors among persons living with diabetes, using an objective assessment (biothesiometer), is unknown in our study ...
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Impact of Myo B Basti on Type 2 Diabetes Mellitus Patients with Low Body Mass Index
Rohit Sane,
Rahul Mandole,
Gurudatta Amin,
Harshita Gupta
Issue:
Volume 8, Issue 1, March 2023
Pages:
12-15
Received:
24 January 2023
Accepted:
21 February 2023
Published:
3 March 2023
Abstract: Type 2 Diabetes Mellitus (T2DM) is a syndrome characterized by a dysregulated metabolism and genetic immune-mediated involvement, and it progressively gets worse with the appearance of life-threatening complications and pathological changes that cause cardiac issues. A negative calorie balance with a low-carb diet is a very effective tool to manage T2DMwith a reduction in orally administered antihyperglycemic agents (OHA) support. As per the twin cycle hypothesis, negative calorie balance can reduce insulin resistance by the reduction in excess adipose tissue but in normal to low BMI T2DM, weight reduction is not advisable. So, the concept of a low-carb and low-calorie diet for good glycemic control is difficult to apply. This study aimed to evaluate impact of 240 ml of Sneha Basti (Myo B Basti: per rectal oil-based herbal formulation) along with an 800 cal/day (Prameh) diet to achieve good glycemic control in T2DM patients with low body mass index. The Myo B Basti shows a mean change of HbA1c in one month from 9.44 to 8.15mmol/mol. Myo B Basti was found to significantly improve HbA1c, BMI, body weight, abdominal girth, SBP, and DBP at the end of the study period i.e., 30th day. Allopathic dependency was also reduced to a great extent. Despite of an 800cal/day diet no major weight loss was observed. Thus, it can be concluded that Myo B Basti can be used as an efficient and safe therapeutic alternative for the treatment of T2DM.
Abstract: Type 2 Diabetes Mellitus (T2DM) is a syndrome characterized by a dysregulated metabolism and genetic immune-mediated involvement, and it progressively gets worse with the appearance of life-threatening complications and pathological changes that cause cardiac issues. A negative calorie balance with a low-carb diet is a very effective tool to manage...
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Impact of Balya Protex Powder on Fatigue Levels in Patients with Diabetes Mellitus Adhering to the Ayurveda-Based Comprehensive Diabetic Care Program
Rohit Sane,
Rahul Mandole,
Gurudatta Amin,
Pravin Ghadigaonkar,
Harshita Gupta
Issue:
Volume 8, Issue 1, March 2023
Pages:
16-20
Received:
9 February 2023
Accepted:
1 March 2023
Published:
24 March 2023
Abstract: Chronic fatigue in diabetic patients can be the outcome of protein deficiency. Plant based protein is closer to nature and bodily acceptable, hence we chose to assess plant-based protein “Balya Protex Powder” over whey protein. A prospective, multicentre, post-market study was conducted in India. Patients with a diagnosis of diabetes mellitus aged 18 years and above were included in this study. All patients adhered to the Comprehensive Diabetic Care (CDC) Program. Comparative data of change in fatigue score was collected retrospectively from type 2 diabetes mellitus patients assigned a low carbohydrate low calorie diet for 90 days. A total of 101 patients were included in this study, 50 patients consumed the Balya Protex Powder whilst 51 did not consume the Balya Protex powder whilst adhering to the CDC program. Weight of the patients decreased by 7.92% and 5.52% in the Balya Protex Powder consumption and Balya Protex Powder non-consumption group, respectively. Body mass index decreased by 5.93% and 5.18% in the Balya Protex Powder consumption and Balya Protex Powder non-consumption group, respectively. Abdomen girth decreased by 8.39% and 4.67% in the Balya Protex Powder consumption and Balya Protex Powder non-consumption group, respectively. Weakness grade decreased by 83.69% and 47.61% in the Balya Protex Powder consumption and Balya Protex Powder non-consumption group, respectively. All patients showed significant reduction in glycated hemoglobin (HbA1c) levels, however patients in the subgroup who were taking 30 gm of Balya Protex Powder daily showed 50% greater reduction in chronic fatigue score. It can be concluded that Balya Protex Powder consumption leads to good glycemic control with reduced fatigue in diabetic patients whilst adhering to the CDC program.
Abstract: Chronic fatigue in diabetic patients can be the outcome of protein deficiency. Plant based protein is closer to nature and bodily acceptable, hence we chose to assess plant-based protein “Balya Protex Powder” over whey protein. A prospective, multicentre, post-market study was conducted in India. Patients with a diagnosis of diabetes mellitus aged ...
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Diabetes Prevalence and Associated Factors in the Adult Population Aged 25–64 in the Humbo Districts of Woliata Zone
Samson Abebe,
Wondimagegn Paulos,
Rea Tschopp
Issue:
Volume 8, Issue 1, March 2023
Pages:
21-27
Received:
20 December 2022
Accepted:
9 January 2023
Published:
20 April 2023
Abstract: The burden of disease caused by NCDs is quickly growing in emerging nations, with substantial social, economic, and health repercussions. However, data on the prevalence of diabetes and related variables among adults aged 25–64 years in Ethiopia, particularly in drought-stricken areas, is limited. The goal of this study is to find out how common diabetes is and what variables contribute to it in the middle-aged population. From January to February 2020, a community-based cross-sectional survey was undertaken among adults aged 25–64 years in Humbo district, southern Ethiopia. 587 people were chosen using a multi-stage sampling process. Weight, height, and fasting blood glucose levels were all measured. To enter data into a computer, Epi Data version 3.1 was utilized, which was subsequently exported to SPSS version 20 for analysis. Descriptive statistics and bivariate and multivariate logistic regression analyses were performed, and statistical significance was determined at a p-value of less than 0.05. Diabetes was found in 5.9% of the research participants (95 percent CI: 3.8–7.8). Age 45–54 (AOR = 4.80, 1.25, 18.32), physical inactivity (AOR = 5.33, 1.37, 20.72), family history of diabetes mellitus (AOR = 6.34, 95 percent CI: 2.43, 16.55), and obesity (AOR = 3.26, 95 percent CI: 1.43, 7.42) were all significantly associated with diabetes, according to multivariable logistic regression. The findings demonstrated the need for implementing educational public policies to encourage population behavior changes in order to prevent and control diabetes.
Abstract: The burden of disease caused by NCDs is quickly growing in emerging nations, with substantial social, economic, and health repercussions. However, data on the prevalence of diabetes and related variables among adults aged 25–64 years in Ethiopia, particularly in drought-stricken areas, is limited. The goal of this study is to find out how common di...
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