Tensile Strength of Single Collagen Fibrils Isolated from Tendons
Issue:
Volume 5, Issue 1, February 2017
Pages:
1-6
Received:
28 November 2016
Accepted:
7 January 2017
Published:
16 February 2017
Abstract: Tensile failure properties of single collagen fibrils were determined using our original tensile test method. Fibrils were directly isolated from the fascicles of mouse tail tendons. Both the ends of each fibril were wound onto the tips of two microneedles several times using micromanipulators. The fibril and tips were immersed in physiological saline solution. Then, the fibril was stretched to failure by moving the one microneedle. During tensile testing, the fibril was firmly attached to the tips of the microneedles, and broken between the tips with no slippage observed. The diameter of tested 10 fibrils was 410±60 nm (Mean±S.D.). The stress-strain curves of these fibrils were almost linear. Their tensile strength and failure strain were 100±32 MPa and 34±11%, respectively. These values were approximately 480 and 190% of those of the fascicles with the diameter of 81±12 m, respectively.
Abstract: Tensile failure properties of single collagen fibrils were determined using our original tensile test method. Fibrils were directly isolated from the fascicles of mouse tail tendons. Both the ends of each fibril were wound onto the tips of two microneedles several times using micromanipulators. The fibril and tips were immersed in physiological sal...
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Evaluation of Structural Properties and Isotopic Abundance Ratio of Biofield Energy Treated (The Trivedi Effect®) Magnesium Gluconate Using LC-MS and NMR
Mahendra Kumar Trivedi,
Alice Branton,
Dahryn Trivedi,
Gopal Nayak,
Alan Joseph Balmer,
Dimitrius Anagnos,
Janice Patricia Kinney,
Joni Marie Holling,
Joy Angevin Balmer,
Lauree Ann Duprey-Reed,
Vaibhav Rajan Parulkar,
Parthasarathi Panda,
Kalyan Kumar Sethi,
Snehasis Jana
Issue:
Volume 5, Issue 1, February 2017
Pages:
7-16
Received:
31 January 2017
Accepted:
14 February 2017
Published:
25 February 2017
Abstract: The current research work was designed to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on magnesium gluconate for the change in the structural properties and isotopic abundance ratio (PM+1/PM and PM+2/PM) by using LC-MS and NMR spectroscopy. Magnesium gluconate was divided into two parts – one part was control, and another part was treated with The Trivedi Effect®- Biofield Energy Healing Treatment remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect® Treated sample. The LC-MS analysis of the both control and treated samples revealed the presence of the mass of the protonated magnesium gluconate at m/z 415 at the retention time of 1.53 min with similar fragmentation pattern. The relative peak intensities of the fragment ions of the treated sample were significantly changed compared with the control sample. The proton and carbon signals for CH, CH2 and CO groups in the proton and carbon NMR spectra were found almost similar for the control and the treated samples. The isotopic abundance ratio analysis revealed that the isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 17O/16O or 25Mg/24Mg) in the treated sample was significantly increased by 34.33% compared with the control sample. Subsequently, the percentage change of the isotopic abundance ratio of PM+2/PM (18O/16O or 26Mg/24Mg) was significantly decreased in the treated sample by 64.08% as compared to the control sample. Briefly, 13C, 2H, 17O, and 25Mg contributions from (C12H23MgO14)+ to m/z 416; 18O and 26Mg contributions from (C12H23MgO14)+ to m/z 417 in the treated sample were significantly changed compared with the control sample. Thus, the treated magnesium gluconate could be valuable for designing better pharmaceutical and/or nutraceutical formulations through its changed physicochemical and thermal properties, which might be providing better therapeutic response against various diseases such as diabetes mellitus, allergy, aging, inflammatory diseases, immunological disorders, and other chronic infections. The Biofield Energy Treated magnesium gluconate might be supportive to design the novel potent enzyme inhibitors by using its kinetic isotope effects.
Abstract: The current research work was designed to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on magnesium gluconate for the change in the structural properties and isotopic abundance ratio (PM+1/PM and PM+2/PM) by using LC-MS and NMR spectroscopy. Magnesium gluconate was divided...
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Urban Noise: A Case Study in Dire-Dawa City, Ethiopia
Belay Sitotaw Goshu,
Hailemariam Mamo,
Solomon Zerihun
Issue:
Volume 5, Issue 1, February 2017
Pages:
17-26
Received:
20 December 2016
Accepted:
6 January 2017
Published:
2 March 2017
Abstract: Urban noise pollution is one of the problems of the people who live in urban area and it is a cause of health and social problem. The main purpose of this work is to identify the major cause of the pollution and to determine the noise pollution levels in the city. A study was conducted on the main roads of Dire-Dawa city using digital Sound Level Meter (SLM). A case study was illustrated by applying standardized methods to find noise pollution in the city. It was found that the noise levels in overall city were very high and above the permissible limits. The result revealed that in the selected area of hospitals, the noise pollution is 103.68 and 104.27 dB during morning and in afternoon respectively. In general, the average values of the noise levels throughout the study area were between 45 and 95 dB in places of bargele and Medirbabur respectively.
Abstract: Urban noise pollution is one of the problems of the people who live in urban area and it is a cause of health and social problem. The main purpose of this work is to identify the major cause of the pollution and to determine the noise pollution levels in the city. A study was conducted on the main roads of Dire-Dawa city using digital Sound Level M...
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