Age-Dependent Impairment of Heart Muscle Contractility as a Primary Mechanism for Overexpression of Na+/Ca2+ Exchanger in Brain Cortex Tissues
Lilia Narinyan,
Sinerik Ayrapetyan
Issue:
Volume 7, Issue 2, December 2019
Pages:
27-42
Received:
19 July 2019
Accepted:
15 August 2019
Published:
29 August 2019
Abstract: The cognitive function of brain and contractility of heart muscle are accompanied with age-dependent dehydration of tissues of these two organs. The aim of the present study is to reveal which of the abovementioned two organs primarily fail as a result of dysfunction of age-sensitive metabolic mechanism. For this purpose, the age-dependent sensitivity of cell hydration in brain cortex and heart muscle tissues are studied through depressing metabolic activity by cooling and its activation by supplying animals with distilled water, by inactivation of Na+/K+ pump and activation of Na+/Ca2+ exchange in the reverse mode. The obtained data bring us to the conclusion that the metabolic regulation of brain cortex and heart muscle tissues has different nature. The age-dependent dysfunction of Na+/K+ pump–induced activation of RNa+/Ca2+ exchange leads to dysfunction of heart muscle contractility because of activation of Ca-calmoduline-NO-cGMP production, which brings to FNa+/Ca2+ exchange induced muscle relaxation and it could serve as a primary mechanism for dysfunction of brain tissues’ metabolic control of cell hydration, which leads to overexpression of Na+/Ca2+ exchanger in the membrane.
Abstract: The cognitive function of brain and contractility of heart muscle are accompanied with age-dependent dehydration of tissues of these two organs. The aim of the present study is to reveal which of the abovementioned two organs primarily fail as a result of dysfunction of age-sensitive metabolic mechanism. For this purpose, the age-dependent sensitiv...
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Overview of the Role of Nurses in the Implementation of Education in Patients Hallucinations
LivanaLivana P. H.,
Titik Suerni
Issue:
Volume 7, Issue 2, December 2019
Pages:
43-45
Received:
10 June 2019
Accepted:
12 July 2019
Published:
17 September 2019
Abstract: The number of individuals experiencing mental disorders every year is increasing both in Central Java and in Indonesia. Mental disorders can occur in all individuals. Individuals who have mental disorders will definitely have some limitations in meeting their daily needs Mental patients need to get the right treatment, so the role of nurses is needed especially in providing education. In implementing nursing care, nurses have roles and functions including providing health education, care givers, as family advisors, disease prevention, counseling, collaboration, ethical decision makers. The purpose of this study was to determine the role of nurses in the implementation of education in hallucinatory patients. The research using descriptive survey design. the sample of this study was nurses in Larasati's room. This research was conducted in the Larasati room of regional psychiatric hospital Dr. Amino Gondohutomo, Central Java, Indonesian in December 2017. This study used a documentation research tool derived from patient medical records. The results showed that nurses provide education to patients who experience hallucinations by helping to recognize hallucinations and symptoms and provide an implementation strategy by rebuking when the patient hears something. After the client has carried out an implementation strategy by rebuking then the patient is given medication according to the medical prescription.
Abstract: The number of individuals experiencing mental disorders every year is increasing both in Central Java and in Indonesia. Mental disorders can occur in all individuals. Individuals who have mental disorders will definitely have some limitations in meeting their daily needs Mental patients need to get the right treatment, so the role of nurses is need...
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The Impact of Family Psycho-education Therapy on Family Burden in Caring for Older Adult with Dementiain Bogor
Livana Ph,
Yossie Susanti Eka Putri
Issue:
Volume 7, Issue 2, December 2019
Pages:
46-51
Received:
12 June 2019
Accepted:
13 August 2019
Published:
9 October 2019
Abstract: Dementia is a prevalent health problem and major cause of disability and dependency among older adults (WHO, 2012). Family, as primary support system, should be able to provide care for older adult with dementia. In provision of care, family may deal with problems which perceived as either physical or psychological problems. Family psycho-education is one of specialist nursing interventions provided for family in caring for older adult with dementia (Tang et al, Varcarolis 2014). This study aimed to identify impact of family psycho-education therapy on family burden in caring for older adult with dementia. The study design wasquasi experiment pre and post test with control group. The study population was family who provided care for older adult with dementia. Study sample consisted of 26 families of intervention group and 26 families of control group, whom selected through purposive sampling method. The intervention was conducted in 5 sessions by providing module and logbook to the families. Questionnaire of Zarit Caregiver Burden Interview was employed for data collection and independent t-test was applied to analyze the data with statistical significance of 0,000. The result indicated a significant difference in family caregiving burden between the intervention and control group following the intervention. Family psycho-education therapymay relieve family burden in caring for older adult with dementia. Psychiatric nurse specialist is encouraged to implement family psycho-education therapy which may affect family’s competency in providing care for older adult with dementia.
Abstract: Dementia is a prevalent health problem and major cause of disability and dependency among older adults (WHO, 2012). Family, as primary support system, should be able to provide care for older adult with dementia. In provision of care, family may deal with problems which perceived as either physical or psychological problems. Family psycho-education...
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The Importance of Computerized Analysis on Spoilage of Maize (Zea Mays L), Before Harvest and Storage in Osun State, Nigeria
Issue:
Volume 7, Issue 2, December 2019
Pages:
52-60
Received:
30 May 2019
Accepted:
9 October 2019
Published:
13 November 2019
Abstract: This research work was carried out, to find the importance of computerized analysis on spoilage of maize (Zea mays L), before harvest and storage in Osun State, Nigeria. 4 Local governments, namely: (Ife East, Ife South, Ife Central and Ife North), local government areas were sampled. 4,000 open questionnaires were distributed to the 4 Local Governments, out of which 1000 was used for farmers, in each local government. A total of 40 different locations were visited in all the four Local Governments, out of which 100 questionnaires were used for farmers in each location. It was gathered that above 70% of the farmers from the four local governments, supported the importance of computerized analysis on spoilage of maize (Zea mays L), before harvest and storage in Osun State, Nigeria, while below 30% of the people could not even understand whether there was any needy, on the importance of computerized analysis on spoilage of maize (Zea mays L), before harvest and storage in Osun State, Nigeria or not. The results from the questionnaires when using Pearson two-tailed correlation coefficient revealed that there was a significant difference from the summary data collected from the farmers within the four local government areas visited and sampled, (p > 0.05) table 5. This shows a strong positive correlation, which implying that, the importance of computerized analysis on spoilage of maize before harvest and storage in Osun State, Nigeria. is strongly influenced and enhanced the farmers and people’s support, and, had therefore, made this research work to become a reality, (p > 0.05), table 5. The reasons may be due to the fact that, maize (Zea mays L), is not only rich in dietary D and calories which are a good source of energy to our body, it is however served as the most productive grain crops in the middle and northern belts of Nigeria where sunshine is adaptable and rainfall is moderate. And as a basic raw materials to thousands of industrial products that may includes: alcoholic, beverages, pharmaceutical, food sweeteners, food cereals, cosmetic and films, gums, package, textile, paper industries and so on., it is one of African’s dominant food crop, that can be consumed in varied forms, such as: maize flour for confectionaries, semo (for swallow with soup), as corn beef, mill (for animals feeding), as roaster corn, it can be boiled or prepared as porridge. Pie chart was used to depict the summary data of each of the local government areas sampled in Ile – Ife Kingdom, of Osun State Nigeria.
Abstract: This research work was carried out, to find the importance of computerized analysis on spoilage of maize (Zea mays L), before harvest and storage in Osun State, Nigeria. 4 Local governments, namely: (Ife East, Ife South, Ife Central and Ife North), local government areas were sampled. 4,000 open questionnaires were distributed to the 4 Local Govern...
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