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Comparison of Sonography and MRI in Diagnosis of Rotator Cuff Injuries
Sied Kazem Razavi Ratki,
Masoud Nakhaie-Nejad,
Nasim Namiranian,
Hamid reza Shafai Arani,
Mona Ghasemian,
Reza Nafisi-Moghadam
Issue:
Volume 1, Issue 3, September 2015
Pages:
35-37
Received:
15 July 2015
Accepted:
24 July 2015
Published:
28 July 2015
Abstract: Background and Objectives: Rotator cuff injuries are problems commonly encountered in athletic and non-athletic patients. Its definite diagnosis is also important. Accordingly, this study was performed to determine the diagnostic accuracy of ultra-sonography (US) compared with magnetic resonance imaging (MRI) in cases with suspicion of rotator cuff injuries. Methods and materials: In this prospective comparative study, 130 patients who had undergone shoulder arthroscopy and open rotator cuff repairing and confirm rotator cuff tears have been enrolled and evaluated with both ultrasonography and MRI methods. Results: The overall sensitivity (95% confidence interval[CI]) of US was 87.64% (78.55-93.37), the specificity (95%CI) was 89.02% (61.24-95.45). The overall sensitivity (95% confidence interval) of MRI was 91.31% (75.47-94.4) and the specificity (95%CI) of MRI was 83.02% (61.23-91.45). There was no statistical significance between sensitivity of two methods (p-value: 0.092). Conclusions: Totally, according to our findings and comparison with other similar studies, it could be concluded that ultrasonography has a good diagnostic modality in patients suspicious to rotator cuff tearing compared with MRI as a more diagnostic imaging test. Accordingly, its use is recommended in patients suspicious to have rotator cuff tearing
Abstract: Background and Objectives: Rotator cuff injuries are problems commonly encountered in athletic and non-athletic patients. Its definite diagnosis is also important. Accordingly, this study was performed to determine the diagnostic accuracy of ultra-sonography (US) compared with magnetic resonance imaging (MRI) in cases with suspicion of rotator cuff...
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Figure-of-Eight Wire Sternal Closure Technique Can Reduce Post-Open Cardiovascular Surgery Chest Re-Exploration and Pain Scores in Diabetic Patients with Severe Obesity (Body Mass Index: 35-40)
Seyed Jalil Mirhosseini,
Sadegh Ali-Hassan-Sayegh,
Seyed Mohammad Yousof Mostafavi-Pour-Manshadi,
Nafiseh Naderi,
Maryam Hadibarhaghtalab,
Mohammad Reza Lotfaliani
Issue:
Volume 1, Issue 3, September 2015
Pages:
38-41
Received:
8 June 2015
Accepted:
10 August 2015
Published:
11 August 2015
Abstract: Background. Postoperative sternal instability can be associated with the density of bone and type of wire closure. Sternal instability is a serious complication, especially in diabetic obese patients. This category of patients is susceptible to activation of inflammation and inflammatory and/or infective involvement of the sternum after sternotomy. This study was designed to evaluate the comparison of safety and efficacy of figure-of-eight with simple wire sternal closure technique in high-risk diabetic severe obese patients [Body mass index (BMI): 35-40]. Methods and materials. This study, conducted on 80 diabetic patients with severe obesity (BMI: 35-40) undergoing elective off-pump coronary artery bypass graft (CABG) surgery in duration from the first day to two weeks after surgery. Sternal wire closure techniques are divided into two groups, group A (n=40), patients undergoing simple wire closure and group B (n=40), patients undergoing figure-of-eight wire closure. Results. The average age of patients was 64.7±13.2 years. According to the patient self-rated numeric pain intensity scale, the pain of sternum related to existing of wire closure was classified to mild [(group A: n=14), (group B: n=17)], moderate [(group A: n=14), (group B: 19)], and severe [(group A: n=12), (group B: 4)]. Postoperative pain scores had significant higher difference in simple closure than figure-of-eight technique. From all patients, three cases with figure-of-eight and seven cases with simple wire closure had chest re-exploration after surgery. Chest re-exploration in group of figure-of-eight was lower than group of simple closure significantly (p=0.03). Postoperative utilization of inotropic agents, mediastinitis, cerebrovascular accident (CVA) and atrial fibrillation (AF) had not significant differences between both techniques. Conclusion. These findings show that figure-of-eight sternal wire closure technique can reduce postoperative pain scores and chest re-exploration significantly in diabetic patients with severe obesity.
Abstract: Background. Postoperative sternal instability can be associated with the density of bone and type of wire closure. Sternal instability is a serious complication, especially in diabetic obese patients. This category of patients is susceptible to activation of inflammation and inflammatory and/or infective involvement of the sternum after sternotomy....
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Comparison Efficacy of Onion Extract plus Heparin with Flucinolone Acetonide on Midsternotomy Hypertrophic Scars Following Open Heart Surgery
Seyed Jalil Mirhosseini,
Sadegh Ali-Hassan-Sayegh,
Alireza Vahidi Mehrjardi,
Maryam Hadibarhaghtalab,
Seyed Mohammad Yousof Mostafavi-Pour-Manshadi,
Nafiseh Naderi,
Mohammad Reza Lotfaliani
Issue:
Volume 1, Issue 3, September 2015
Pages:
42-45
Received:
8 June 2015
Accepted:
10 August 2015
Published:
11 August 2015
Abstract: Background. Post-midsternotomy hypertrophic scars can lead to remarkable morbidities such as pigmentation alteration, pain, tenderness, induration, itching, and erythema so that they may be cosmetically and emotionally unacceptable to the patient undergoing midsternotomy. Initially, wound healing is induced rapidly with re-epithelialization, whereas tissue remodeling occurs several months later to create a regular scar. This study was undertaken to evaluate the efficacy of onion extract plus heparin versus Fluocinolone acetonide on scar formation after midsternotomy in patients who are candidates for coronary bypass graft (CABG) surgery. Materials and Methods. One hundred patients undergoing off- pump coronary artery bypass graft (CABG) surgery were randomly assigned into two groups, group A, onion extract plus heparin (n=50), and group B, flucinolone acetonide (n=50). After performing midsternotomy for accessing to intra-chest cavity, the target vessel was exposed and snared above the anastomosis site with zero to four sutures and a soft plastic snugger was applied to prevent coronary injury. A skilled surgeon sutured incisions of the midsternotomy. The topical treatments (gel) were started one week post operation. Subjects were then asked to return to cardiovascular center three months after the surgery for evaluation of their wounds and condition of their scars. The postoperative parameters such as indurations, erythema, pigmentation alteration, itching, cosmetic appearance, raised area of the incision, tenderness, sternal wound infection, and duration of incision improvement were evaluated by method of Vancouver scar scale. Results. The average age of all the patients was 63.8±11, 63±11.5 was related to fluocinolon acetonide group (FA) and 64±10 related to onion extract plus heparin group (OEH). Postoperative rise in scar area was observed in 63 cases, 28 cases (56%) in OEH and 35 cases (70%) in FA (p=0.14). Postoperative erythema and itching had not significant differences in both groups, therefore, onion extract plus heparin could not diminish these complications after open heart surgery (p>0.05). Conclusion. Onion extract plus heparin significantly decreased pigmentation alternation, duration of incision improvement, and tenderness after midsternotomy.
Abstract: Background. Post-midsternotomy hypertrophic scars can lead to remarkable morbidities such as pigmentation alteration, pain, tenderness, induration, itching, and erythema so that they may be cosmetically and emotionally unacceptable to the patient undergoing midsternotomy. Initially, wound healing is induced rapidly with re-epithelialization, wherea...
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Neuroprotective Effects of Purslane Seeds against Adverse Effects Induced by Experimental Hyperlipidemia on Frontal Cortex and Cerebellum in Young Male Albino Rats
El Sayed Aly Mohamed Metwally,
Fardous Soror Karawya
Issue:
Volume 1, Issue 3, September 2015
Pages:
46-59
Received:
13 August 2015
Accepted:
6 September 2015
Published:
9 September 2015
Abstract: Background. Hyperlipidemia is characterized by abnormally elevated levels of lipids and is positively associated with cerebrovascular diseases. Alzheimer’s disease (AD) is a chronic brain disorder characterized by cognitive impairment, inflammation, β-amyloid deposition, and vascular damage. Recent studies have shown that high cholesterol levels are linked to the pathology of AD. Purslane seeds are medicinal plants rich in unsaturated fatty acids (omega-3), antioxidants, and fibers. They are known to have antidiabetic and antiatherogenic activities. The aim of this research is to study the structural alterations occurring in the frontal cortex and cerebellum after feeding high cholesterol diet, and the possible protective role of purslane seeds. Materials and methods. Forty male albino rats were used in the study. They were divided into three groups; control group (20 rats), hypercholesterolemic group (10 rats) who were fed the balanced diet supplemented with cholesterol at a dose of 2 gm/100 gm diet, and protected group (10 rats) who were fed the same previous hypercholesterolemic diet concomitant with purslane seed 20% (20 gm/100 ml water). After 3 months, blood samples were collected from all rats for biochemical estimation and fresh specimens were taken from the frontal cortex and cerebellum of each rat and processed for; light microscopic examination using H&E and Orcein stains. Results. Significant increase of serum triglyceride (TG), total cholesterol (TC), and low-density lipoprotein (LDL-C) levels in hyperlipidemic rats were detected. Associated structural changes in the frontal cortex of the rats were evident as pyknotic nuclei of degenerated neurons, loss of neuron, dilation and congestion of blood vessels, expanded perivascular space, and increased vacuolar spaces of neuropil. The cerebellar cortex of the rats fed on high cholesterol diet revealed pyknotic nuclei of degenerated neuron and decrease in the number of Purkinje and granule cells compared to the control group. Concomitant administration of purslane seeds revealed evident amelioration of biochemical and most of the structural changes. Conclusion. We concluded that a high cholesterol diet has deleterious biochemical changes associated with structural alteration in the frontal cortex and cerebellum and purslane seeds ameliorate most of these changes.
Abstract: Background. Hyperlipidemia is characterized by abnormally elevated levels of lipids and is positively associated with cerebrovascular diseases. Alzheimer’s disease (AD) is a chronic brain disorder characterized by cognitive impairment, inflammation, β-amyloid deposition, and vascular damage. Recent studies have shown that high cholesterol levels ar...
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Effect of Phylloquinone on Dexamethasone-Induced Calcification of Heart Muscle and Media Elastocalcinosis in Aorta Artery in Rat Model
Mohammad Rezaeisadrabadi,
Mohammad Hossein Dashti-Rahmatabadi,
Shamin Ghobadi,
Fatemeh Haddad,
Shokouh Taghipour Zahir,
Mansour Ahmadi,
Mohammad Reza Lotfaliani,
Aghdas Mirjalili,
Ali Rezaei
Issue:
Volume 1, Issue 3, September 2015
Pages:
60-64
Received:
12 August 2015
Accepted:
8 September 2015
Published:
9 September 2015
Abstract: Background. Dexamethasone is a type of steroid medication which enhances the rate of pericyte differentiation and mineralization in vitro with concomitant suppression of calcification inhibitory molecule matrix Gla-protein (MGP). Vitamin K is an essential cofactor in the carboxylation of glutamate residues in a small group of proteins, including MGP. This study tries to assess the efficacy of vitamin K1 on dexamethasone-induced media elastocalcinosis in aorta artery and heart muscle in a rat model. Materials and Methods. 110 male rats with a normal weight range of 270 ± 20 were enrolled in this study. They received a calcification-inducing diet containing both vitamin K1 and dexamethasone during 6 or 12 weeks and were randomly assigned into two groups; a basic group (n=30), and an experimental group (n=80). The experimental group was divided into two groups receiving treatment during 6 and 12 weeks. Administration of dexamethasone was 0.5 mg/kg, intraperitoneal (IP). Vitamin K intakes were different including 5, 10, and 20 µg/kg, which were considered as low, moderate, and high intake, respectively. Results. Plasma concentrations of calcium were not affected by the different regimes and ranged between 2.27 and 2.31 millimolar (mM) (mean ± SD: 2.29 ± 0.02). According to the findings of pathologic biopsy of aorta artery and heart muscle, treatment of 0.5 mg/kg dexamethasone during 6 and 12 weeks did not induce media elastocalcinosis at all. Conclusion. Administration of 0.5 mg/kg dexamethasone during 6 and 12 weeks did not induce media elastocalcinosis at all. On the other hand, structure and histology of vessels did not change following intake of vitamin K1, therefore, different dosages of vitamin K could not affect the aorta artery status.
Abstract: Background. Dexamethasone is a type of steroid medication which enhances the rate of pericyte differentiation and mineralization in vitro with concomitant suppression of calcification inhibitory molecule matrix Gla-protein (MGP). Vitamin K is an essential cofactor in the carboxylation of glutamate residues in a small group of proteins, including MG...
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