International Journal of Clinical and Experimental Medical Sciences

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Volume 5, Issue 5, September 2019

  • Effects of Periconceptual Omega-3-Fatty Acid Supplementation on in Vitro Fertilization Success and Miscarriage Rates in Patients of a German Fertility Centre

    Arasch Bareksei, Gerd Hafner, Sebastian Pfeiffer, Kathrin Schlatterer

    Issue: Volume 5, Issue 5, September 2019
    Pages: 62-66
    Received: 6 September 2019
    Accepted: 27 September 2019
    Published: 10 October 2019
    DOI: 10.11648/j.ijcems.20190505.11
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    Abstract: Long-chain omega-3 fatty acids have been positively related with improvement of fertility in both women and men. Primary natural source of omega-3- fatty acids is seafood. As this also can bei the source of toxicants like f.e. lead, mercury and cadmium, reproductive benefits may be counteracted. Therefore, our approach was to supplement pharmaceuti... Show More
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  • D-dimer Increasing After First Alemtuzumab Administration in a Multiple Sclerosis Patient

    Stefania Federica De Mercanti, Simona Rolla, Manuela Matta, Marco Iudicello, Emanuele Franchin, Marinella Clerico

    Issue: Volume 5, Issue 5, September 2019
    Pages: 67-69
    Received: 19 August 2019
    Accepted: 4 September 2019
    Published: 11 October 2019
    DOI: 10.11648/j.ijcems.20190505.12
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    Abstract: Alemtuzumab is a humanized anti-CD52 monoclonal antibody used for the treatment of high activity relapsing multiple sclerosis (R-MS). The most common adverse event is an infusion reaction due to cytokine-release. Autoimmunity can arise from months to years after treatment and encompasses Grave’s disease and thrombocytopenia. Recent reports of strok... Show More
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  • Correlation Between Immunological Laboratory Status of Omega-3-Fatty-Acid-Supplemented Patients of a German Fertility Centre and Outcome of IVF-Treatment

    Arasch Bareksei, Gerd Hafner, Sebastian Pfeiffer, Kathrin Schlatterer

    Issue: Volume 5, Issue 5, September 2019
    Pages: 70-79
    Received: 6 September 2019
    Accepted: 24 September 2019
    Published: 17 October 2019
    DOI: 10.11648/j.ijcems.20190505.13
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    Abstract: A well-defined group of patients of a German Fertility Centre, all supplemented periconceptually with omega-3-fatty acids, was monitored for specific alterations in the immunological laboratory status in correlation with the outcome of in-vitro-fertilization-(IVF)-treatment. For 36 of 52 IVF-patients IVF-treatment was successful. Patients with IVF-... Show More
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  • Superiority of the Rapid Von Willebrand Factor (VWF) VWF:GPIbR and VWF:GPIbM Assays in Type 2A, 2B and 2M Von Willebrand Disease

    Jan Jacques Michiels, Petr Smejkal, Katarzina Mayger, Gary Moore, Jan Blatny, Miroslav Penka, Ulrich Budde, Zwi Berneman, Inge Vangenechten, Alain Gadisseur

    Issue: Volume 5, Issue 5, September 2019
    Pages: 80-91
    Received: 9 July 2019
    Accepted: 30 August 2019
    Published: 23 October 2019
    DOI: 10.11648/j.ijcems.20190505.14
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    Abstract: A complete set of rapid activity and classical von Willebrand factor (VWF) assays for Willebrand disease (VWD) diagnosis was used in the present study to characterize VWD type 1, 2A, 2B and 2M patients due to mutations in the A1, A2 and A3 domains. The VWF:RCo/VWF:Ag, VWF:GPIbM/VWF:Ag and VWF:GPIbR/VWF:Ag ratios at cuttt off value of 0.7 separated ... Show More
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